Uba1 - ubiquitin-like modifier activating enzyme 1 Gene

种属: Rattus norvegicus

同用名: Ube1x

关于 Uba1

功能概要

Predicted to enable ubiquitin activating Enzyme activity. Predicted to be involved in cellular response to DNA damage stimulus; protein ubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Predicted to colocalize with bounding membrane of organelle; desmosome; and heterochromatin. Human ortholog(s) of this gene implicated in VEXAS syndrome and X-linked spinal muscular atrophy 2. Orthologous to human UBA1 (ubiquitin like modifier activating Enzyme 1). [provided by Alliance of Genome Resources, Apr 2022]