2. Gene
  3. Brd3 - bromodomain containing 3 Gene

Brd3 - bromodomain containing 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：含溴结构域 3

种属: Rattus norvegicus

基因 ID: 362092 | 基因类型: protein coding

关于 Brd3

Primary_assembly 3: 10,775,272-10,829,577 reverse strand.mRatBN7.2:CM026976.1

This gene has 2 transcripts (splice variants), 150 orthologues, 11 paralogues and is associated with 4 phenotypes. Biased expression in Adrenal (RPKM 15.2), Lung (RPKM 86.3) and 9 other tissues.

功能概要

预测该基因编码的蛋白可启动赖氨酸乙酰化组蛋白结合活性和核小体组蛋白结合活性。预计通过 RNA 聚合酶 II 参与染色质重塑和转录调控。预计在染色质和细胞核中有活性。与人类 BRD3 同源（含 3 的溴结构域）。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable lysine-acetylated histone binding activity and nucleosomal histone binding activity. Predicted to be involved in chromatin remodeling and regulation of transcription by RNA polymerase II. Predicted to be active in chromatin and nucleus. Orthologous to human BRD3 (bromodomain containing 3). [provided by Alliance of Genome Resources, Apr 2022]

Brd3 基因产物(1)

mRNA Protein Name
NM_001108575.1 NP_001102045.1 bromodomain-containing protein 3

Brd3 蛋白结构

Bromo_Brdt_I_like

Bromo_Brdt_I_like: cd05497 (33 - 139)

Bromo_Brdt_II_like

Bromo_Brdt_II_like: cd05498 (310 - 411)

BET

BET: pfam17035 (587 - 651)

  • 0
  • 200
  • 400
  • 600
  • 742 a.a.
蛋白主名 其他名称

bromodomain-containing protein 3

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-112090 ABBV-744 Inhibitor 99.97% Phase 1
Pre-clinical Phase
生物活性分子 (24)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-100972 ARV-771 Inhibitor 99.87% 否
HY-136570 GSK778 Inhibitor 98.93% 否
HY-136571 GSK046 Inhibitor 99.65% 否
HY-101519 BETd-260 Inhibitor 99.59% 否
HY-141438 SIM1 Inhibitor 99.57% 否
HY-112429 HJB97 Inhibitor 98.05% 否
HY-120000 MS402 Inhibitor 99.62% 否
HY-138563 GSK973 Inhibitor 99.97% 否
HY-130622 LT052 Inhibitor 98.77% 否
HY-114504 RVX-297 Inhibitor 95.00% 否
HY-112610 CF53 Inhibitor 99.78% 否
HY-114416 GS-626510 Inhibitor 99.80% 否
HY-131061 BET bromodomain inhibitor 1 Inhibitor 99.91% 否
HY-145264 OARV-771 Inhibitor 98.33% 否
HY-110215 XD14 Inhibitor 95.02% 否
HY-126325 BY27 Inhibitor / 否
HY-168635 SJ46420 Inhibitor / 否
HY-169170 PARP1/BRD4-IN-3 Inhibitor / 否
HY-155680 BET BD2-IN-1 Inhibitor / 否
HY-143471 WNY0824 Inhibitor / 否
HY-168634 SJ46421 Inhibitor / 否
HY-170390 AB3067 Degrader / 否
HY-152213 BET-IN-13 Inhibitor / 否
HY-136570A GSK778 hydrochloride Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Brd3 NCBI NCBI:8019
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z