1. Gene
  2. LDLR - low density lipoprotein receptor Gene

LDLR - low density lipoprotein receptor Gene

中文名称:低密度脂蛋白受体

种属: Homo sapiens

同用名: FH; FHC; FHCL1; LDLCQ2

基因 ID: 3949 | 基因类型: protein coding

关于 LDLR

Cytogenetic location: 19p13.2 Genomic coordinates (GRCh38): 19:11,089,463-11,133,820 (from NCBI)

This gene has 14 transcripts (splice variants), 129 orthologues, 14 paralogues and is associated with 4 phenotypes. Ubiquitous expression in adrenal (RPKM 29.0), lung (RPKM 28.5) and 25 other tissues.

功能概要

低密度脂蛋白受体 (LDLR) 基因家族由参与受体介导的特定配体内吞作用的细胞表面蛋白组成。编码的蛋白质通常结合在细胞膜上,在那里它结合低密度脂蛋白/胆固醇并被带入细胞。溶酶体释放胆固醇,可用于抑制微粒体酶 3-羟基-3-甲基戊二酰辅酶 A (HMG CoA) 还原酶,这是胆固醇合成中的限速步骤。同时,发生胆固醇酯合成的相互刺激。该基因的突变会导致常染色体显性遗传病,即家族性高胆固醇血症。交替剪接导致多个转录变体。[RefSeq 提供,2022 年 5 月]

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. The encoded protein is normally bound at the cell membrane, where it binds low density lipoprotein/Cholesterol and is taken into the cell. Lysosomes release the Cholesterol, which is made available for repression of microsomal Enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in Cholesterol synthesis. At the same time, a reciprocal stimulation of Cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2022]

LDLR 基因产物(6)

mRNA Protein Name
NM_000527.5 NP_000518.1 low-density lipoprotein receptor isoform 1 precursor
NM_001195798.2 NP_001182727.1 low-density lipoprotein receptor isoform 2 precursor
NM_001195799.2 NP_001182728.1 low-density lipoprotein receptor isoform 3 precursor
NM_001195800.2 NP_001182729.1 low-density lipoprotein receptor isoform 4 precursor
NM_001195803.2 NP_001182732.1 low-density lipoprotein receptor isoform 6 precursor
NM_001406861.1 NP_001393790.1 low-density lipoprotein receptor isoform 7
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
26526611 GOA
enables low-density lipoprotein particle binding IMP
IMP: 通过突变表型推断
6299582 GOA
enables low-density lipoprotein particle receptor activity IDA
IDA: 通过直接分析推断
6091915 GOA
enables low-density lipoprotein particle receptor activity IMP
IMP: 通过突变表型推断
6299582 GOA
enables molecular adaptor activity EXP
EXP: 通过实验结果推断
22091758 GOA
enables protease binding IPI
IPI: 通过物理相互作用推断
22081141 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
10571240 GOA
enables very-low-density lipoprotein particle receptor activity IDA
IDA: 通过直接分析推断
8626535 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to low-density lipoprotein particle stimulus IMP
IMP: 通过突变表型推断
6299582 GOA
involved in cholesterol homeostasis IGI
IGI: 通过遗传相互作用推断
24412220 GOA
involved in cholesterol homeostasis IMP
IMP: 通过突变表型推断
6299582 GOA
involved in cholesterol import IMP
IMP: 通过突变表型推断
6299582 GOA
involved in cholesterol transport IMP
IMP: 通过突变表型推断
17142622 GOA
involved in intestinal cholesterol absorption IMP
IMP: 通过突变表型推断
17142622 GOA
involved in long-term memory IGI
IGI: 通过遗传相互作用推断
24412220 GOA
involved in low-density lipoprotein particle clearance IMP
IMP: 通过突变表型推断
6299582 GOA
involved in negative regulation of low-density lipoprotein particle clearance IDA
IDA: 通过直接分析推断
17452316 GOA
involved in negative regulation of receptor recycling IDA
IDA: 通过直接分析推断
17452316 GOA
involved in receptor-mediated endocytosis involved in cholesterol transport IMP
IMP: 通过突变表型推断
6299582 GOA
involved in regulation of protein metabolic process IGI
IGI: 通过遗传相互作用推断
24412220 GOA
involved in response to caloric restriction IGI
IGI: 通过遗传相互作用推断
24412220 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
17461796 GOA
part of PCSK9-LDLR complex IDA
IDA: 通过直接分析推断
22081141 GOA
part of PCSK9-LDLR complex IPI
IPI: 通过物理相互作用推断
22081141 GOA
located in cell surface IDA
IDA: 通过直接分析推断
17461796 GOA
located in clathrin-coated pit IDA
IDA: 通过直接分析推断
6091915 GOA
located in early endosome IDA
IDA: 通过直接分析推断
15166224 GOA
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
15166224 GOA
located in late endosome IDA
IDA: 通过直接分析推断
17461796 GOA
located in lysosome IDA
IDA: 通过直接分析推断
15166224 GOA
part of receptor complex IDA
IDA: 通过直接分析推断
23382219 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

LDLR 蛋白结构

Ldl_recept_a

Ldl_recept_a: Low-density lipoprotein receptor domain class A (26 - 63)

Ldl_recept_a

Ldl_recept_a: Low-density lipoprotein receptor domain class A (67 - 104)

Ldl_recept_a

Ldl_recept_a: Low-density lipoprotein receptor domain class A (107 - 143)

Ldl_recept_a

Ldl_recept_a: Low-density lipoprotein receptor domain class A (147 - 184)

Ldl_recept_a

Ldl_recept_a: Low-density lipoprotein receptor domain class A (196 - 231)

Ldl_recept_a

Ldl_recept_a: Low-density lipoprotein receptor domain class A (235 - 270)

Ldl_recept_a

Ldl_recept_a: Low-density lipoprotein receptor domain class A (276 - 313)

FXa_inhibition

FXa_inhibition: Coagulation Factor Xa inhibitory site (318 - 348)

EGF_CA

EGF_CA: Calcium-binding EGF domain (354 - 392)

Ldl_recept_b

Ldl_recept_b: Low-density lipoprotein receptor repeat class B (439 - 483)

Ldl_recept_b

Ldl_recept_b: Low-density lipoprotein receptor repeat class B (487 - 526)

Ldl_recept_b

Ldl_recept_b: Low-density lipoprotein receptor repeat class B (529 - 569)

Ldl_recept_b

Ldl_recept_b: Low-density lipoprotein receptor repeat class B (573 - 614)

Ldl_recept_b

Ldl_recept_b: Low-density lipoprotein receptor repeat class B (616 - 656)

FXa_inhibition

FXa_inhibition: Coagulation Factor Xa inhibitory site (673 - 711)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 860 a.a.
蛋白主名 其他名称

low-density lipoprotein receptor

LDL receptor

LDLR 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
LDLR P01130 TLE5 Homo sapiens Q08117-2
Validated Y2H
32296183
种属内
LDLR P01130 TLE5 Homo sapiens Q08117-2
Y2H Prey Pooling
32296183
种属内
LDLR P01130 TLE5 Homo sapiens Q08117-2
Y2H Array
32296183
种属内
LDLR P01130 APOE Homo sapiens P02649
NMR
24447298
种属内
LDLR P01130 APOE Homo sapiens P02649
NMR
20030366
种属内
LDLR P01130 APOE Homo sapiens P02649
SPR
24447298
种属内
LDLR P01130 PCSK9 Homo sapiens Q8NBP7-1
GMS
18753623
种属内
LDLR P01130 PCSK9 Homo sapiens Q8NBP7-1
Anti Bait CoIP
18753623
种属内
LDLR P01130 APOH Homo sapiens P02749
Fluorescence Spectr
20223219
种属内
LDLR P01130 APOH Homo sapiens P02749
FPS
20223219
种属内
LDLR P01130 APOH Homo sapiens P02749
NMR
20223219
种属内
LDLR P01130 MTIF3 Homo sapiens Q9H2K0
Validated Y2H
32296183
种属内
LDLR P01130 MTIF3 Homo sapiens Q9H2K0
Y2H Array
32296183
种属内
LDLR P01130 MTIF3 Homo sapiens Q9H2K0
Y2H Prey Pooling
32296183
种属内
LDLR P01130 APOB Homo sapiens P04114
NMR
24447298
种属内
LDLR P01130 LRPAP1 Homo sapiens P30533
NMR
20030366
种属内
LDLR P01130 PCSK9 Homo sapiens Q8NBP7
SPR
22081141
种属内
LDLR P01130 PCSK9 Homo sapiens Q8NBP7
X-Ray Diffraction
22081141
种属内
LDLR P01130 PCSK9 Homo sapiens Q8NBP7
BN-PAGE
25613181
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 LDLR 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70235 LDLR Protein, Human (HEK293, His) P01130-1 (A22-R788) ≥95%
HY-P72392 LDLR Protein, Human (Biotinylated, HEK293, Avi-His) P01130-1 (A22-R788) ≥95%
HY-P700860 LDLR Protein, Human (HEK293, Avi-His) P01130-1 (A22-R788) ≥95%

关联疾病

疾病名称 别名
Hypercholesterolemia, Familial, 1

Hypercholesterolemia

FHCL1

Fhc

Fh

Hyperlipoproteinemia, Type Ii

Hyperlipoproteinemia, Type Iia

Hyper-Low-Density-Lipoproteinemia

Hypercholesterolemic Xanthomatosis, Familial

Ldl Receptor Disorder

Hypercholesterolemia, Susceptibility To

Hypercholesterolemia, Familial, Modifier Of

Hypercholesterolemia, Familial, Due To Ldlr Defect, Modifier Of

Ldl Cholesterol Level Qtl2

Hyperlipoproteinemia Type Ii

Hypercholesterolemia, Familial, Type 1

High Cholesterol

Increased Cholesterol

Low-Density-Lipoid-Type Hyperlipoproteinemia

Pure Hypercholesterolaemia

Ldl - [Low Density Lipoprotein} Hyperlipoproteinemia

Group A Hyperlipidaemia

Pure Hypercholesterinaemia

Cholesterolaemia

Essential Cholesterolaemia

Essential Hypercholesterolaemia

Group A Hyperlipemia

Increased Low Density Lipoprotein

Low-Density-Lipoprotein-Type

Low-Density-Lipoprotein-Type Hyperlipoproteinemia

Homozygous Familial Hypercholesterolemia

Hofh

Familial Hypercholesterolemia

Hyperlipoproteinemia Type Iia

Familial Hyperbetalipoproteinaemia

Familial Hypercholesteremia

Fredrickson Type Iia Hyperlipoproteinemia

Fredrickson Type Iia Lipidaemia

Hyperbetalipoproteinemia

Type Ii Hyperlipidemia

Familial Hypercholesterolæmia

Familial Hypercholesterolaemia

Fh

Hypercholesterolemia Familial

Hyperlipoproteinemia Type Ii

Hypercholesterolemia, Familial

Carotid Artery Occlusion

Occlusion And Stenosis Of Carotid Artery

Carotid Artery Dissection

Dissection Of Carotid Artery

Lipid Metabolism Disorder

Dyslipidemia

Disorder Of Fatty Acid Metabolism

Lipid Metabolism Disorders

Fatty Acid Metabolism Disorder

Disorder Of Lipid Metabolism

Abnormality Of Lipid Metabolism

Lipid Metabolism, Inborn Errors

Dyslipidemias

Disorders Of Lipid Metabolism

Congenital Disorders Of Lipid Metabolism

Inherited Disorders Of Lipid Metabolism

Coronary Heart Disease 5

Coronary Heart Disease, Susceptibility To, 5

CHDS5

Coronary Artery Disease, Early-Onset

Coronary Artery Disease Early-Onset

Early-Onset Coronary Artery Disease

Heart, Coronary, Disease, Susceptibility To, Type 5

Hyperlipoproteinemia, Type Iii

Hyperlipoproteinemia Type Iii

Broad-Betalipoproteinemia

Floating-Betalipoproteinemia

Familial Type 3 Hyperlipoproteinemia

Broad Beta Disease

Familial Hyperbeta- And Prebetalipoproteinemia

Familial Hypercholesterolemia With Hyperlipemia

Hyperlipemia With Familial Hypercholesterolemic Xanthomatosis

Coronary Artery Disease, Severe, Susceptibility To

Coronary Artery Disease, Severe

Hyperlipidemia Type 3

Familial Dysbetalipoproteinemia

Hyperlipoproteinemia Type 3

Coronary Artery Disease

Apolipoprotein E, Deficiency Or Defect Of

Dysbetalipoproteinemia Due To Defect In Apolipoprotein E-D

Carbohydrate Induced Hyperlipemia

Familial Hypercholesterolaemia With Hyperlipaemia

Remnant Hyperlipidemia

Remnant Removal Disease

Dysbetalipoproteinemia

Broad-Beta Disease

Familial Dyslipidemia Type 3

Hlp Type 3

Remnant Hyperlipoproteinemia

Familial Hyperlipoproteinemia Type Iii

CAD

Hyperlipoproteinemia 3

HLPP3

Deficiency Or Defect Of Apolipoprotein E

Dysbetalipoproteinemia Due To Defect In Apolipoprotein E

Coronary Arteriosclerosis

Coronary Heart Disease

Aortic Dissection
Stroke, Ischemic

Cerebral Infarction

Stroke

Ischemic Stroke

Cerebrovascular Accident

Cerebral Infarction, Susceptibility To

Stroke, Ischemic, Susceptibility To

Cerebral Infarct

Ischemic Stroke, Susceptibility To

Stroke, Susceptibility To

Cva - Cerebral Infarction

ISCHSTR

Ischemic Cerebrovascular Accident

Stomatitis
Familial Hyperlipidemia

Familial Hyperlipoproteinemia

Hyperlipidaemia

Hyperlipoproteinemias

Hyperlipidemia

Hyperlipemia

Hyperlipidemias

Hypercholesterolemia, Familial, 2

Hypercholesterolemia, Autosomal Dominant, Type B

FHCL2

Apolipoprotein B-100, Familial Defective

Apolipoprotein B-100, Familial Ligand-Defective

Hypercholesterolemia, Familial, Due To Ligand-Defective Apolipoprotein B

Autosomal Dominant Type B Hypercholesterolemia

Familial Ligand-Defective Apolipoprotein B-100

Fdb

Hypercholesterolemia, Familial, Type 2

Hyperlipoproteinemia Type Iib

Hypercholesterolemia, Familial, 4

Hypercholesterolemia, Autosomal Recessive

Arh

FHCL4

Autosomal Recessive Hypercholesterolemia

Arh1

Arh2

Autosomal Recessive Hypercholesterolemia 1

Autosomal Recessive Hypercholesterolemia 2

Fhcb1

Fhcb2

Hypercholesterolemia, Autosomal Recessive, 1, Formerly

Arh1, Formerly

Fhcb1, Formerly

Hypercholesterolemia, Autosomal Recessive, 2, Formerly

Arh2, Formerly

Fhcb2, Formerly

Familial Autosomal Recessive Hypercholesterolemia

Hypercholesterolemia, Familial, Autosomal Recessive

Hypercholesterolemia, Familial, Type 4

Arcus Corneae

Arcus Senilis

Corneal Arcus

Arcus Of Cornea

Hyperalphalipoproteinemia 1

Hyperalphalipoproteinemia

HALP1

Cetp Deficiency

Cholesterol-Ester Transfer Protein Deficiency

Familial Hyperalphalipoproteinemia

Cholesteryl Ester Transfer Protein Deficiency

Cept Deficiency

Cholesterol Ester Transfer Protein Deficiency

Osteoporosis-Pseudoglioma Syndrome

OPPG

Ops

Osteoporosis With Pseudoglioma

Osteogenesis Imperfecta, Ocular Form

Ocular Form Of Osteogenesis Imperfecta

Osteogenesis Imperfecta Ocular Form

Osteoporosis Pseudoglioma Syndrome

Pseudoglioma With Bone Fragility

Hepatitis C Virus

Hepatitis C Virus, Susceptibility To

Hepatitis C Virus Infection, Response To Therapy Of

Hcv

Hcv, Susceptibility To

Hepatitis C Virus, Resistance To

Hepatitis C Virus, Response To Therapy Of

Resistance To Hepatitis C Virus

Smith-Lemli-Opitz Syndrome

SLOS

Rsh Syndrome

7-Dehydrocholesterol Reductase Deficiency

Slo Syndrome

Rutledge Lethal Multiple Congenital Anomaly Syndrome

Lethal Acrodysgenital Syndrome

Polydactyly, Sex Reversal, Renal Hypoplasia, And Unilobar Lung

Smith-Opitz-Inborn Syndrome

Polydactyly, Sex Reversal, Renal Hypoplasia, And Unilobular Lung

Smith Lemli Opitz Syndrome

Smith-Lemli-Opitz Syndrome, Type Ii

Xanthomatosis

Xanthomatosis, Susceptibility To

Xanthelasmatosis

Coronary Heart Disease 1

Coronary Heart Disease

Coronary Heart Disease, Susceptibility To, 1

Chds1

Coronary Heart Disease, Susceptibility To

CHD

Heart, Coronary, Disease, Susceptibility To, Type 1

Coronary Arteriosclerosis

Coronary Artery Disease

Heart Disease

Heart Failure

Congenital Heart Disease

Heart Diseases

Congenital Heart Defects

Congenital Heart Defect

Heart Malformation

Congenital Anomaly Of Heart

Heart Defect

Heart-Congenital Defect

Congenital Heart Disorder

Heart Defects Congenital

Heart Defects, Congenital

Heart Defects

Heart Disease, Congenital

Disease, Heart, Congenital

Congestive Heart Failure

Hypobetalipoproteinemia, Familial, 1

Hypobetalipoproteinemia

Familial Hypobetalipoproteinemia 1

Familial Hypobetalipoproteinemia

FHBL1

Hypobetalipoproteinemia, Familial

Fhbl

Acanthocytosis With Hypobetalipoproteinemia

Hypobetalipoproteinemias

Hypobetalipoproteinemia, Normotriglyceridemic

Hypo-Beta-Lipoproteinemia

Hypobetalipoprotéinemia, Familial

Normotriglyceridemic Hypobetalipoproteinemia

Hypobetalipoproteinemia, Familial, Type 1

Hypoalphalipoproteinemia
Lipoprotein Quantitative Trait Locus

Coronary Artery Disease

Coronary Artery Anomaly

Coronary Artery Disease, Susceptibility To

Myocardial Ischemia

Congenital Anomaly Of Coronary Artery

Coronary Arteriosclerosis

Coronary Disease

Coronary Heart Disease

Coronary Artery Disorder

LPAQTL

Lpa Deficiency, Congenital

Coronary Artery Abnormality

Coronary Artery Anomaly, Congenital

Chd

Coronary Syndrome

Congenital Malformations Of Coronary Vessels

Malformation Of Coronary Vessels

Congenital Coronary Artery Anomaly

Congenital Coronary Artery Deformity

Congenital Coronary Artery Disorder

Abnormal Coronary Artery

Congenital Coronary Artery Malposition

Congenital Coronary Disease

Congenital Anomaly Of Coronary Arteries

Atherosclerosis Susceptibility

Atherosclerosis

Atherosclerosis, Susceptibility To

ATHS

Atherogenic Lipoprotein Phenotype

Alp

Arteriosclerosis

Hyperlipidemia, Familial Combined, 3

Familial Combined Hyperlipidemia

Combined Hyperlipidemia, Familial

Mixed Hyperlipidaemia

FCHL3

Hyperlipidemia, Familial Combined

Familial Multiple Lipoprotein-Type Hyperlipidemia

Hyperbetalipoproteinemia With Prebetalipoproteinemia

Type Iib Hyperlipoproteinemia

Hyperlipidemia Familial Combined

Hyperlipoproteinemia Type Iib

Mixed Hyperlipemia

Hyperlipidaemia, Group C

Familial Hypercholesterolaemia With Hyperlipaemia

Familial Hyperbetalipoproteinaemia And Hyperprebetalipoproteinaemia

Hyperbetalipoproteinaemia With Prebetalipoproteinaemia

Hypercholesterolaemia With Endogenous Hyperglyceridaemia

Prebetalipoproteinemia Hyperbetalipoproteinaemia

Remnant Hyperlipoproteinemia

Hepatoblastoma
Hypothyroidism

Thyroid Diseases

Thyroid Disease

Thyroid Deficiency

Thyroid Insufficiency

Dysfunction Thyroid

Thyroid Dysfunction

Vascular Disease

Vascular Diseases

Aneurysm

Spinal Cord Ischemia

Vascular Anomaly

Spinal Cord Vascular Diseases

Vascular Tissue Disease

Cardiovascular System Disease

Abnormality Of The Cardiovascular System

Cardiovascular Disease

Disease Of Subdivision Of Hemolymphoid System

Disorder Of Cardiovascular System

Cardiovascular Diseases

Myocardial Infarction

Heart Attack

Myocardial Infarction, Susceptibility To

Myocardial Infarction 1

Myocardial Infarction, Protection Against

Myocardial Infarction, Decreased Susceptibility To

Myocardial Infarction, Decreased

Myocardial Infarct

MCI1

Premature Myocardial Infarction

Myocardial Infarction, Susceptibility To, Type 1

Alzheimer Disease, Familial, 1

Alzheimer Disease

Alzheimer'S Disease

Presenile And Senile Dementia

AD1

Alzheimer Disease, Susceptibility To

Alzheimer Disease, Late-Onset, Susceptibility To

Alzheimer Disease 1, Familial

AD

Familial Alzheimer Disease

Alzheimer Disease, Late-Onset

Alzheimers Dementia

Alzheimer Dementia

Alzheimer Sclerosis

Alzheimer Syndrome

Alzheimer-Type Dementia

Dat

Primary Senile Degenerative Dementia

Sdat

Alzheimer Disease 1

Autosomal Dominant Alzheimer Disease

Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy

Late Onset Alzheimer Disease

Alzheimers Disease

Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy

Late-Onset Alzheimers Disease

Alzheimer'S Disease Pathway Kegg

Dementia Due To Alzheimer'S Disease

Alzheimer Disease Type 1

Alzheimers

Type 2 Diabetes Mellitus

Insulin Resistance

NIDDM

Type 2 Diabetes

Diabetes Mellitus, Non-Insulin-Dependent

T2D

Noninsulin-Dependent Diabetes Mellitus

Diabetes Mellitus, Type Ii

Maturity-Onset Diabetes

Insulin Resistance, Severe, Digenic

Diabetes Mellitus, Type 2

Diabetes Mellitus, Noninsulin-Dependent

Diabetes Mellitus, Noninsulin-Dependent, Association With

Diabetes Mellitus, Noninsulin-Dependent, Late Onset

Hypertension, Insulin Resistance-Related, Susceptibility To

Insulin Resistance, Susceptibility To

Non-Insulin-Dependent Diabetes Mellitus

Type Ii Diabetes Mellitus

Adult-Onset Diabetes Mellitus

Maturity-Onset Diabetes Mellitus

Diabetes Mellitus Type 2

Type Ii Diabetes

Type 2 Diabetes Mellitus, Susceptibility To

Diabetes, Type 2

Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To

Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To

Diabetes Mellitus, Type 2, Susceptibility To

Diabetes Mellitus, Noninsulin-Dependent, 2

Diabetes Mellitus, Type Ii, Susceptibility To

Hypertension, Insulin Resistance-Related

Adult-Onset Diabetes

Aodm

Diabetes Mellitus, Adult-Onset

Diabetes Mellitus Type Ii

Diabetes Mellitus Type 2, Susceptibility To

Diabetes, Type Ii, Susceptibility To

Diabetes Type 2

Diabetes Mellitus

Adult Onset Diabetes

Maturity Onset Diabetes

Nonketotic Diabetes

Non-Insulin Dependent Diabetes Mellitus

T2dm - [Type 2 Diabetes Mellitus]

Niddm - [Non Insulin Dependent Diabetes Mellitus]

Dm2

Dm Type Ii

Diabetic Type 2

Insulin Requiring Type 2 Diabetes

Noninsulin Dependent Diabetes

Non-Insulin-Dependent Diabetes Mellitus Without Complications

Diabetes Due To Insulin Secretory Defect

Diabetes Mellitus Due To Insulin Secretory Defect

Non-Insulin-Dependent Diabetes Of The Young

Senile Diabetes

Nonketotic Hyperglycaemia

Stable Diabetes

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris LDLR VGNC VGNC:42622
Macaca mulatta LDLR VGNC VGNC:74248
Felis catus LDLR VGNC VGNC:68031
Bos taurus LDLR VGNC VGNC:55214
Mus musculus LDLR MGD MGI:96765
Rattus norvegicus LDLR RGD RGD:2998
Macaca fascicularis LDLR NCBI NCBI:102127361
Others LDLR NCBI