1. Gene
  2. PAX5 - paired box 5 Gene

PAX5 - paired box 5 Gene

中文名称:配对盒 5

种属: Homo sapiens

同用名: ALL3; BSAP; PAX-5

基因 ID: 5079 | 基因类型: protein coding

关于 PAX5

Cytogenetic location: 9p13.2 Genomic coordinates (GRCh38): 9:36,833,269-37,034,268 (from NCBI)

This gene has 18 transcripts (splice variants), 199 orthologues, 50 paralogues and is associated with 96 phenotypes. Biased expression in lymph node (RPKM 16.7), spleen (RPKM 9.5) and 3 other tissues.

功能概要

该基因编码配对盒 (PAX) 转录因子家族的成员。该基因家族的核心特征是一种新颖的、高度保守的 DNA 结合基序,称为配对盒。配对盒转录因子是早期发育的重要调节因子,其基因表达的改变被认为有助于肿瘤转化。该基因编码 B 细胞谱系特异性激活蛋白,该蛋白在 B 细胞分化的早期而非晚期表达。在发育中的中枢神经系统和睾丸中也检测到它的表达,因此编码的蛋白质也可能在神经发育和精子发生中发挥作用。该基因位于 9p13,它参与 t (9;14) (p13;q32) 易位,该易位在浆细胞样亚型的小淋巴细胞淋巴瘤和衍生的大细胞淋巴瘤中反复出现。这种易位将 IgH 基因的有效 E-mu 增强子带到 PAX5 启动子附近,表明该基因转录的失调有助于这些淋巴瘤的发病机制。可变剪接导致编码不同异构体的多个转录变体。[RefSeq 提供,2013 年 7 月]

This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

PAX5 基因产物(11)

mRNA Protein Name
NM_001280547.2 NP_001267476.1 paired box protein Pax-5 isoform 2
NM_001280548.2 NP_001267477.1 paired box protein Pax-5 isoform 3
NM_001280549.2 NP_001267478.1 paired box protein Pax-5 isoform 4
NM_001280550.2 NP_001267479.1 paired box protein Pax-5 isoform 5
NM_001280551.2 NP_001267480.1 paired box protein Pax-5 isoform 6
NM_001280552.2 NP_001267481.1 paired box protein Pax-5 isoform 7
NM_001280553.2 NP_001267482.1 paired box protein Pax-5 isoform 8
NM_001280554.2 NP_001267483.1 paired box protein Pax-5 isoform 9
NM_001280555.2 NP_001267484.1 paired box protein Pax-5 isoform 10
NM_001280556.2 NP_001267485.1 paired box protein Pax-5 isoform 11
NM_016734.3 NP_057953.1 paired box protein Pax-5 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
24735925 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

PAX5 蛋白结构

PAX

PAX: 'Paired box' domain (16 - 140)

Pax2_C

Pax2_C: Paired-box protein 2 C terminal (282 - 390)

  • 0
  • 100
  • 200
  • 300
  • 391 a.a.
蛋白主名 其他名称

paired box protein Pax-5

B-cell lineage specific activator

PAX5 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
PAX5 Q02548 PNMA5 Homo sapiens Q96PV4
Validated Y2H
32296183
种属内
PAX5 Q02548 UBE2I Homo sapiens Q7KZS0
Y2H Array
32296183
种属内
PAX5 Q02548 UBE2I Homo sapiens Q7KZS0
Y2H Prey Pooling
32296183
种属内
PAX5 Q02548 UBE2I Homo sapiens Q7KZS0
Validated Y2H
32296183
种属内
PAX5 Q02548 GRHL2 Homo sapiens Q6ISB3
Validated Y2H
32296183
种属内
PAX5 Q02548 NEIL2 Homo sapiens Q969S2
Validated Y2H
32296183
种属内
PAX5 Q02548 CIB3 Homo sapiens Q96Q77
Validated Y2H
32296183
种属内
PAX5 Q02548 SEC14L4 Homo sapiens Q9UDX3
Validated Y2H
32296183
种属内
PAX5 Q02548 KRTAP9-3 Homo sapiens Q9BYQ3
Validated Y2H
32296183
种属内
PAX5 Q02548 TLK2 Homo sapiens Q86UE8
Validated Y2H
32296183
种属内
PAX5 Q02548 GNG13 Homo sapiens Q9P2W3
Validated Y2H
32296183
种属内
PAX5 Q02548 ACOT12 Homo sapiens Q8WYK0
Validated Y2H
32296183
种属内
PAX5 Q02548 NFYC Homo sapiens Q13952-2
Validated Y2H
32296183
种属内
PAX5 Q02548 CXorf38 Homo sapiens Q8TB03
Validated Y2H
32296183
种属内
PAX5 Q02548 LARP4 Homo sapiens Q6P4E2
Validated Y2H
32296183
种属内
PAX5 Q02548 ZMYM5 Homo sapiens Q9UJ78-2
Validated Y2H
32296183
种属内
PAX5 Q02548 ZMYM5 Homo sapiens Q9UJ78-2
Y2H Prey Pooling
32296183
种属内
PAX5 Q02548 ZMYM5 Homo sapiens Q9UJ78-2
Y2H Array
32296183
种属内
PAX5 Q02548 UBXN2B Homo sapiens Q14CS0
Validated Y2H
32296183
种属内
PAX5 Q02548 LONRF1 Homo sapiens Q17RB8
Validated Y2H
32296183
种属内
PAX5 Q02548 HMBOX1 Homo sapiens Q6NT76
Validated Y2H
32296183
种属内
PAX5 Q02548 Q03164-PRO_0000390949 Homo sapiens Q03164-PRO_0000390949
Anti Bait CoIP
24735925
种属内
PAX5 Q02548 STAC Homo sapiens Q99469
Validated Y2H
32296183
种属内
PAX5 Q02548 NGLY1 Homo sapiens Q96IV0
Validated Y2H
32296183
种属内
PAX5 Q02548 KLHL38 Homo sapiens Q2WGJ6
Validated Y2H
32296183
种属内
PAX5 Q02548 HGS Homo sapiens O14964
Y2H Prey Pooling
32296183
种属内
PAX5 Q02548 DTX2 Homo sapiens Q86UW9
Validated Y2H
32296183
种属内
PAX5 Q02548 SAE1 Homo sapiens Q9UBE0
Validated Y2H
32296183
种属内
PAX5 Q02548 LDLRAP1 Homo sapiens Q5SW96
Validated Y2H
32296183
种属内
PAX5 Q02548 AIRIM Homo sapiens Q9NX04
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

PAX5 抗体

目录号 产品名 应用 反应物种
HY-P82852 PAX5 Antibody (YA2597) WB, IHC-P, ICC/IF, FC Human, Mouse

关联疾病

疾病名称 别名
Leukemia, Acute Lymphoblastic

Acute Lymphoblastic Leukemia

ALL

Acute Lymphocytic Leukemia

Leukemia, Acute Lymphocytic, Susceptibility To, 1

Acute Lymphoblastic Leukaemia

Precursor Lymphoblastic Lymphoma/Leukemia

Precursor Lymphoid Neoplasm

Leukemia, Acute Lymphoblastic, Susceptibility To

B-Cell Acute Lymphoblastic Leukemia

Leukemia, Acute Lymphocytic 1

Acute Lymphocytic Leukaemia

Acute Lymphoblastic Leukemia/Lymphoma

All1

Childhood Acute Lymphoblastic Leukemia

Leukemia Acute Lymphoblastic 1

Leukemia Acute Lymphoblastic B-Hyperdiploid

Leukemia Acute Lymphocytic

Leukemia Acute Lymphocytic 1

Leukemia B-Cell Acute Lymphoblastic

Leukemia T-Cell Acute Lymphoblastic

Leukemia, Acute Lymphoblastic, 3

ALL3

Lymphoblastic Leukemia Acute

Leukemia, Acute, Lymphoblastic

Precursor Cell Lymphoblastic Leukemia Lymphoma

Leukemia, Lymphocytic, Acute, L1

Leukemia, Acute Lymphoblastic, Susceptibility To, 3

Leukemia, Acute Lymphoblastic 3

Leukemia, Acute Lymphoblastic, Susceptibility To, 3

ALL3

Precursor B-Cell Acute Lymphoblastic Leukemia

B-All

Precursor B-Cell Acute Lymphoblastic Leukemia/Lymphoma

Precursor B-Cell Acute Lymphocytic Leukemia

Precursor B-Cell Acute Lymphocytic Leukemia/Lymphoma

Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

Burkitt Lymphoma

Precursor B-Cell Lymphoblastic Leukemia

B-Lymphoblastic Leukemia/Lymphoma With Recurrent Genetic Abnormality
Lymphoplasmacytic Lymphoma

Waldenstrom Macroglobulinemia

Malignant Lymphoma - Lymphoplasmacytic

Waldenström Macroglobulinaemia

Waldenström Macroglobulinaemia Without Mention Of Remission

Idiopathic Macroglobulinaemia

Primary Macroglobulinaemia

Splenic Marginal Zone Lymphoma

Smzl

Splenic Marginal Zone B-Cell Lymphoma

B-Lymphoblastic Leukemia/Lymphoma

B Lymphoblastic Leukemia/Lymphoma

B-All

Precursor B Lymphoblastic Lymphoma/Leukemia

C-All

Lymphoblastic Lymphoma, Nos

Common Precursor B All

Lymphoblastic B-Cell Lymphoma

Pro-B All

B-Precursor Lymphoma

Lbl - [Lymphoblastic Lymphoma]

Anaplastic Large Cell Lymphoma

Alcl

Cd30 Positive Anaplastic Large Cell Lymphoma

Ki-1 Positive Anaplastic Large Cell Lymphoma

Primary Systemic Alcl

Sacl

Ki-1+ Anaplastic Large Cell Lymphoma

Lymphoma

Lymphoid Cancer

Lymphomas

Lymphoid Cancers

Lymphoid Neoplasm

Lymphoma Nos

Nhl - [Non-Hodgkin Lymphoma]

Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma, Nos

Non-Hodgkin Malignant Lymphoma Nos

Acute Leukemia

Stem Cell Leukaemia

Stem Cell Leukemia

Acute Leukemias

Acute Undifferentiated Leukemia

Undifferentiated Leukemia

Acute Leukaemia Of Unspecified Cell Type Without Mention Of Remission

Blast Cell Leukaemia

Blast Leukaemia

Blastic Leukaemia

Undifferentiated Leukaemia

Merkel Cell Carcinoma

Trabecular Adenocarcinoma

Cutaneous Neuroendocrine Carcinoma

Trabecular Carcinoma

Carcinoma, Merkel Cell

Merkel Cell Cancer

Merkle Tumors

Mcc

Carcinoma Merkel Cell

Burkitt Lymphoma

Burkitt'S Lymphoma

BL

Burkitt Lymphoma, Somatic

Burkitt Lymphoma/Leukaemia

Burkitt'S Tumor

Burkitt'S Tumor Or Lymphoma

Malignant Lymphoma, Burkitt'S Type

Small Non-Cleaved Cell Lymphoma, Burkitt'S Type

Small Non-Cleaved Cell Lymphoma

Burkitt Tumor

Burkitts Lymphoma

Lymphoma, Small Noncleaved-Cell

Burkitt Tumour

Diffuse Small Noncleaved Malignant Burkitt Lymphoma

Malignant Burkitt Lymphoma

“Burkitt-Like” Lymphoma

Undifferentiated Burkitt Lymphoma

Small Noncleaved Cell Burkitt Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstrom Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Waldenström Macroglobulinemia

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstrom'S Macroglobulinaemia

Waldenstrom'S Syndrome

Waldenstrom'S Macroglobulinemia

Wm

Waldenström'S Macroglobulinemia

Malignant Lymphoma - Lymphoplasmacytic

B-Cell Lymphoma

Lymphoma, B-Cell

B-Cell Lymphomas

B-Cell Lymphocytic Neoplasm

Lymphoma B-Cell

B-Cell Lymphoma Nos

Submandibular Adenitis

Submandibular Lymphadenitis

Neuroendocrine Carcinoma

Neuroendocrine Cancer

Carcinoma Neuroendocrine

Carcinoma, Neuroendocrine

Reticulosarcoma

Histiocytic Lymphoma

Large-Cell Lymphomas

Lymphoma, Large-Cell

Lymphoma Large Cell

Diffuse Large B-Cell Lymphoma

Histiocytic Sarcoma

Gray Zone Lymphoma

B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma And Classical Hodgkin Lymphoma

Lymphoma, Hodgkin, Classic

Hodgkin Lymphoma

Hodgkin Disease

Hodgkin'S Lymphoma

Hodgkins Lymphoma

Classic Hodgkin Lymphoma

CHL

Hodgkin Lymphoma, Susceptibility To

Hl

Hodgkin'S Sarcoma

Stage I Subdiaphragmatic Hodgkin Lymphoma

Stage Ii Subdiaphragmatic Hodgkin Lymphoma

Lymphoma, Hodgkin'S

Classic Hodgkin Disease

Hodgkin'S Disease

Lymphoma, Hodgkin, Susceptibility To

Hodgkin'S Disease Of Intrapelvic Lymph Nodes

Hodgkin'S Disease Of Lymph Nodes Of Inguinal Region And/Or Lower Limb

Malignant Lymphogranuloma

Malignant Lymphogranulomatosis

Malignant Hodgkin Lymphoma

Classical Hodgkin Lymphoma, Type Not Specified

Lymphoma, Non-Hodgkin, Familial

Non-Hodgkin Lymphoma

Lymphoma, Non-Hodgkin

NHL

Lymphoma, Non-Hodgkin, Somatic

Lymphoma, Follicular, Somatic

Familial Non-Hodgkin Lymphoma

Lymphoma Non-Hodgkins

Follicular Lymphoma, Somatic

Lymphosarcoma

Non-Hodgkins Lymphoma

Macroglobulinemia

Primary Macroglobulinemia

Waldenstrom Macroglobulinemia

Hodgkin'S Lymphoma, Lymphocytic Depletion

Hodgkin Lymphoma, Lymphocyte Depletion

Hodgkin'S Disease, Lymphocytic Depletion

Hodgkin'S Lymphocytic Depletion Of Unspecified Site

Lymphocyte-Depleted Classical Hodgkin Lymphoma

Classic Hodgkin Lymphoma, Lymphocyte-Depleted Type

Hodgkin Disease, Lymphocytic Depletion

Hodgkin Lymphocytic Depletion

Selective Igg Deficiency Disease

Igg Deficiency

Immunoglobin G Subclass Deficiency

Selective Deficiency Of Igg

Selective Igg Immunodeficiency

Selective Immunoglobulin G Deficiency

Selective Immunoglobulin G Subclass Deficiency

Mediastinal Gray Zone Lymphoma

Mediastinal B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma And Classical Hodgkin Lymphoma

Mediastinal Malignant Lymphoma

Lymphoma Of Mediastinum

Mediastinal Lymphoma

Plasmacytoma

Solitary Plasmacytoma

Solitary Myeloma

Myeloma - Solitary

Myeloma, Solitary

Plasmacytoma - Category

Solitary Osseous Plasmacytoma

Solitary Plasmacytoma Without Mention Of Remission

Localised Malignant Plasma Cell Tumour Nos

Plasmacytoma Nos

B-Lymphoblastic Leukemia/Lymphoma With Bcr-Abl1

B-All With Bcr-Abl1

B-Lymphoblastic Leukemia/Lymphoma With T(9

22)(Q34.1

Q11.2)

Bcr-Abl1

B Lymphoblastic Leukemia/Lymphoma With T(9

22)(Q34.1

Q11.2)

Bcr-Abl1

Lymphoblastic Lymphoma

Lymphoma, Lymphoblastic

Lymphoma Lymphoblastic

Precursor Cell Lymphoblastic Lymphoma

Precursor Cell Lymphoblastic Leukemia Lymphoma

Hodgkin'S Lymphoma, Nodular Sclerosis

Classical Hodgkin Lymphoma, Nodular Sclerosis

Classic Hodgkin Lymphoma, Nodular Sclerosis Type

Nodular Sclerosis Hodgkin Lymphoma

Hodgkin'S Disease, Nodular Sclerosis

Hodgkin Disease, Nodular Sclerosis

Hodgkin Lymphoma, Nodular Sclerosis

Hodgkin Nodular Sclerosis

Tracheal Lymphoma

Lymphoma Of The Trachea

Lymphoma Of Trachea

Peripheral T-Cell Lymphoma

Lymphoma T-Cell Peripheral

Composite Lymphoma

Composite Hodgkin And Non-Hodgkin Lymphoma

Osteoporosis

Postmenopausal Osteoporosis

Osteoporosis, Postmenopausal

Bone Mineral Density Quantitative Trait Locus

Bmnd

Osteoporosis, Involutional

Osteoporosis, Susceptibility To

Osteoporosis, Postmenopausal, Susceptibility

Bone Mineral Density Variation Qtl, Osteoporosis

OSTEOP

Involutional Osteoporosis

Senile Osteoporosis

Osteoporosis Postmenopausal

Bone Mineral Density, Quantitative Trait Locus

Osteoporosis, Senile

Idiopathic Osteoporosis

Bone Rarefaction Nos

Type 1 Osteoporosis

Leukemia, Chronic Lymphocytic

Chronic Lymphocytic Leukemia

B-Cell Chronic Lymphocytic Leukemia

CLL

B-Cell Chronic Lymphoid Leukemia

Chronic Lymphatic Leukemia

Chronic Lymphocytic Leukaemia

Lymphoplasmacytic Leukemia

Small Lymphocytic Lymphoma

Leukemia, Chronic Lymphatic

B-Cell Chronic Lymphocytic Leukaemia

Chronic Lymphatic Leukaemia

Lymphoplasmacytic Leukaemia

B Cell Chronic Lymphocytic Leukemia

Chronic B-Cell Lymphocytic Leukemia

Leukemia, Lymphocytic, Chronic

B-Cll

Chronic Lymphoid Leukemia

Leukemia Lymphocytic Chronic

Lymphoma Small Lymphocytic

Leukemia, Lymphocytic, Chronic, B-Cell

Plasmablastic Lymphoma

Pbl

Immunoblastic Large-Cell Lymphoma

Follicular Lymphoma

Lymphoma, Follicular

Lymphoma Follicular

Brill-Symmers' Disease

Large Cell Follicular Non-Hodgkin Lymphoma

Diffuse Follicle Centre Lymphoma

Diffuse Follicular Lymphoma Nos

Follicular Nodular Non-Hodgkin Lymphoma, Unspecified

Follicular Large Cell Cleaved Or Noncleaved Lymphoma

Large Cell Follicular Noncleaved Lymphoma

Follicular Lymphoma With Or Without Diffuse Areas

Histiocytic Follicular Lymphoma

Histiocytic Nodular Lymphoma

Histiocytic Nodular Malignant Lymphoma

Large Cell Follicular Lymphoma

Large Cell Noncleaved Follicular Lymphoma

Large Cell Noncleaved Follicular Malignant Lymphoma

Nodular Reticulum Cell Sarcoma

Noncleaved Follicular Lymphoma

Hematologic Cancer

Hematologic Neoplasm

Hematologic Neoplasms

Hematologic Malignancies

Blood Cancer

Hematologic Malignancy

Hematological Tumors

Hematopoietic And Lymphoid System Tumor

Hematopoietic Cancer

Hematopoietic Neoplasm

Hematopoietic Tumors

Malignant Hematopoietic Neoplasm

Liquid Tumor

Hematopoietic Neoplasms

Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Cll/Sll

B-Cell Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Icdo:9823/3

Chronic Lymphocytic Leukaemia Of B-Cell Type Without Mention Of Remission

Small Cell B-Cell Lymphoma

Lung Lymphoma

Pulmonary Lymphoma

Lymphoma Of Lung

Primary Lung Lymphoma

Monoclonal Paraproteinemia

Monoclonal Paraproteinaemia

B-Lymphoblastic Leukemia/Lymphoma With Iamp21

B-All With Iamp21

Intrachromosomal Amplification Of Chromosome 21

Primary Hyperparathyroidism

Familial Primary Hyperparathyroidism

Hyperparathyroidism, Primary

Hyperparathyroidism Primary

Hypocalciuric Hypercalcemia, Familial, Type 1

Familial Benign Hypercalcemia

Familial Hyperparathyroidism

Parathyroid Enlargement

Extramedullary Plasmacytoma

Extraosseous Plasmacytoma

Plasmacytoma, Extramedullary

Bone Lymphoma

Lymphoma Of Bone

Lymphoma Of The Bone

Breast Lymphoma

Lymphoma Of Breast

Lymphoma Of The Breast

Malignant Lymphoma Of Breast

Gamma Heavy Chain Disease

Franklin Disease

Franklin'S Disease

Gamma Heavy Chain Deposition Disease

Igg Heavy Chain Disease

Gamma-Heavy Chain Disease

Gamma-Hcd

Gamma-Chain Disease

Multicentric Castleman Disease

Mcd

Multicentric Giant Lymph Node Hyperplasia

Plasmablastic Multicentric Castleman Disease

Pmcd

Idiopathic Multicentric Castleman Disease

Multi-Centric Castleman'S Disease

Idiopathic Multicentric Castleman'S Disease

Multicentric Plasma Cell Variant Of Castleman'S Disease

Hhv-8-Negative Multicentric Castleman Disease

Human Herpesvirus-8-Negative Multicentric Castleman Disease

Marginal Zone B-Cell Lymphoma

Marginal Zone Lymphoma

Mzl

Mucosa-Associated Lymphoid Tissue Lymphoma

Medulloblastoma

MDB

Cpnet

Localized Primitive Neuroectodermal Tumor

Classic Medulloblastoma

Medulloblastoma Predisposition Syndrome

Medulloblastoma, Somatic

Brain Medulloblastoma

Cns Pnet

Infratentorial Primitive Neuroectodermal Tumor

Neuroectodermal Tumors, Primitive

Medulloblastomas

Desmoplastic Medulloblastoma

Medulloblastoma, With Extensive Nodularity

Medulloblastoma Of Unspecified Site

Medullomyoblastoma Of Unspecified Site

Histiocytic And Dendritic Cell Cancer

Histiocytic And Dendritic Cell

Adult Acute Lymphocytic Leukemia

Adult Acute Lymphoid Leukemia

Adult All

Mediastinal Cancer

Mediastinal Neoplasms

Mediastinal Tumor

Mediastinum Cancer

Neoplasm Of Mediastinum

Tumour Of Mediastinum

Malignant Tumor Of Mediastinum

Mature B-Cell Neoplasm

Mature B-Cell Lymphocytic Neoplasm

Neoplasm Of Mature B-Cells

Mature B-Cell Non-Hodgkin Neoplasm With Leukaemic Behaviour

Richter'S Syndrome

Richter Syndrome

Richter Transformation

Adult Lymphoma
Spleen Cancer

Spleen Neoplasm

Splenic Neoplasm

Splenic Neoplasms

Malignant Splenic Tumor

Malignant Tumour Of Spleen

Tumor Of Spleen

Malignant Neoplasm Of Spleen

Central Nervous System Hematologic Cancer

Cns Hematopoietic Tumor

Hematopoietic Neoplasm Of Central Nervous System

Central Nervous System Hematopoietic Neoplasm

Childhood Lymphoma

Pediatric Lymphoma

Angioimmunoblastic T-Cell Lymphoma

Immunoblastic Lymphadenopathy

Lymphogranulomatosis X

T-Cell Lymphoma, Aild Type

Aitl

Ailt

Angioimmunoblastic Lymphadenopathy

Aild - [Angioimmunoblastic Lymphadenopathy With Dysproteinaemia]

Angioimmunoblastic Lymphoma

Acute Biphenotypic Leukemia

Mixed Phenotype Acute Leukemia

Acute Leukemia Of Ambiguous Lineage

Acute Undifferentiated Leukemia

Acute Leukemia Of Indeterminate Lineage

Hybrid Acute Leukemia

Mixed Lineage Acute Leukemia

All With Myeloid Markers

Aml With Lymphoid Markers

Acute Leukemia Of Undetermined Lineage

Bal

Biphenotypic Acute Leukemia

Undifferentiated Acute Leukemia

Mpal

Acute Myeloid Leukemia, Minimal Differentiation, Fab M0

Leukemia, Biphenotypic, Acute

Central Nervous System Lymphoma

Microglioma

Primary Cns Lymphoma

Cns Lymphoma

Primary Central Nervous System Lymphoma

Rhabdomyosarcoma
Appendix Lymphoma

Appendiceal Lymphoma

Chronic Kidney Disease

Chronic Renal Disease

Chronic Kidney Failure

Ckd

Chronic Renal Failure

Kidney Failure, Chronic

Chronic Renal Failure Syndrome

Crf

Renal Failure - Chronic

Renal Failure Chronic

Chronic Kidney Diseases

Chronic Kidney Disease Stage 5

Ckd - [Chronic Kidney Disease]

Crf - [Chronic Renal Failure]

Chronic Kidney Impairment

Chronic Renal Impairment

Chronic Kidney Shutdown

Chronic Hypoxic Kidney Failure

Chronic Kidney Collapse

Chronic Renal Insufficiency

Chronic Kidney Toxaemia

Chronic Kidney Hypofunction

Chronic Renal Suppression

Chronic Renal Failure, Stage 5

Ckd - [Chronic Kidney Disease] Stage 5

End Stage Kidney Failure

End Stage Renal Failure

End Stage Kidney Disease

End Stage Renal Disease

End Stage Chronic Renal Failure

Esrf - [End Stage Renal Failure]

Esrd - [End Stage Renal Diseases]

Egfr - [Estimated Glomerular Filtration Rate] < 15 Ml/Min/1.73m²

Myeloma, Multiple

Multiple Myeloma

Plasma Cell Myeloma

Kahler Disease

Myelomatosis

Medullary Plasmacytoma

Multiple Myeloma, Resistance To

Myeloma

Plasma Cell Dyscrasia

Kahler'S Disease

Multiple Myeloma, Susceptibility To

Myeloma - Multiple

Kahler-Bozzolo Disease

Plasma Cell Myelomas

MM

Plasma Cell Neoplasm

Primary Systemic Amyloidosis

Primary Amyloidosis

Immunoglobulin Deposition Disease

Plasmacytic Myeloma

Multiple Myelomata

Multiple Myeloma Nos

Multiple Myeloma Without Mention Of Remission

Monostotic Plasma Cell Myeloma

Mm - [Multiple Myeloma]

Prion Disease

Spongiform Encephalopathy

Transmissible Spongiform Encephalopathies

Prion Diseases

Prion Disease Pathway

Transmissible Spongiform Encephalopathy

Prion Induced Disorder

Prion Protein Disease

Inherited Human Transmissible Spongiform Encephalopathies

Prion Protein Diseases

Prion-Associated Disorders

Prion-Induced Disorders

Transmissible Dementias

Tses

Human Prion Disease

Tse

Encephalopathy, Transmissible Spongiform

Prion Disease, Susceptibility To

Spongiform Encephalopathies

Human Transmissible Spongiform Encephalopathies, Inherited

Paranasal Sinus Lymphoma

Lymphoma Of Accessory Sinus

Lymphoma Of Paranasal Sinus

Ureteral Lymphoma

Lymphoma Of Ureter

Ureter Lymphoma

Mantle Cell Lymphoma

Lymphoma, Mantle Cell

Lcm

Mcl

Mantle Zone Lymphoma

Lymphoma Mantle-Cell

Lymphoma, Mantle-Cell

Malignant Lymphoma, Lymphocytic, Intermediate Differentiation, Diffuse

Malignant Lymphoma - Lymphocytic, Intermediate Differentiation

Diffuse Small Cleaved-Cell Lymphoma

Diffuse Small Cleaved Cell Malignant Lymphoma

Small Cleaved Cell Non-Hodgkin Lymphoma

Diffuse Non-Hodgkin Small Cleaved Cell Lymphoma

Malignant Lymphomatous Polyposis

Malignant Small Cell, Noncleaved, Diffuse Lymphoma

Malignant Undifferentiated Cell, Non-Burkitt Lymphoma

Cleaved Cell Lymphoma

Small Cell Mantle Cell Lymphoma

Small Cleaved Cell Malignant Lymphoma

Lymphoma, Mucosa-Associated Lymphoid Type

Malt Lymphoma

Gastric Lymphoma, Primary

Lymphoma, Malt, Somatic

Mucosa-Associated Lymphoid Tissue Lymphoma

Extranodal Marginal Zone B-Cell Lymphoma

MALTOMA

Marginal Zone B-Cell Lymphoma

Mucosa-Associated Lymphatic Tissue Lymphoma

Primary Gastric Lymphoma

Gastric Lymphoma

Familial Primary Gastric Lymphoma

Primary Central Nervous System Lymphoma

Pcnsl

Primary Cns Lymphoma

Primary Brain Lymphoma

Primary Lymphoma, Cns

Primary Cerebral Lymphoma

Mature T-Cell And Nk-Cell Lymphoma

Mature T-Cell And Natural Killer Cell Lymphoma

Nk-T Cell Lymphoma

Thrombocytopenia

Low Platelet Count

Low Platelets

Decreased Platelets

Platelet Dysfunction Nos

Renal Pelvis Transitional Cell Carcinoma

Urothelial Cell Carcinoma Of Renal Pelvis

Renal Pelvis Urothelial Carcinoma

Transitional Cell Carcinoma Of Renal Pelvis

Diffuse Large B-Cell Lymphoma

Dlbcl

Diffuse Large B-Cell Lymphoma, Not Otherwise Specified

Large B-Cell Diffuse Lymphoma

Lymphoma, Large B-Cell, Diffuse

Dlbcl - [Diffuse Large B-Cell Lymphoma]

Diffuse Large Beta Cell Lymphoma

Plasma Cell Neoplasm

Plasma Cell Dyscrasia

Paraproteinemias

Plasma Cell Tumour

Plasmacytic Tumor

Multiple Myeloma

Plasmacytoma

Plasma Cell Tumours

Plasma Cells Dyscrasia

Leukemia, Acute Myeloid

Acute Myeloid Leukemia

Leukemia, Acute Myelogenous

Acute Myelogenous Leukemia

AML

Leukemia, Acute Myeloid, Susceptibility To

Acute Myeloblastic Leukemia

Leukemia, Acute Myeloid, Reduced Survival In, Somatic

Acute Myeloid Leukaemia

Leukemia, Myelocytic, Acute

Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome

Secondary Aml

Acute Myelocytic Leukemia

Acute Myeloid Leukemia, Somatic

Leukemia, Acute Myeloid, Somatic

Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic

Acute Myeloblastic Leukaemia

Acute Myelogenous Leukaemia

Aml - Acute Myeloid Leukemia

Acute Myeloid Leukemia With Cebpa Somatic Mutations

Aml With Cebpa Somatic Mutations

Inherited Acute Myeloid Leukemia

Familial Aml

Inherited Aml

Pure Familial Aml

Pure Familial Acute Myeloid Leukemia

Secondary Acute Myeloid Leukemia

Therapy-Related Aml And Myelodysplastic Syndrome

Acute Myeloid Leukemia, Secondary

Acute Non-Lymphoblastic Leukemia

Acute Non-Lymphocytic Leukemia

Acute Biphenotypic Leukemia

Acute Undifferentiated Leukemia

Acute Myeloblastic Leukaemia With Multilineage Dysplasia

Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission

Acute Myeloid Leukaemia With Myelodysplasia-Related Features

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus PAX5 RGD RGD:1565236
Macaca mulatta PAX5 VGNC VGNC:75764
Felis catus PAX5 VGNC VGNC:68700
Bos taurus PAX5 VGNC VGNC:54466
Canis familiaris PAX5 VGNC VGNC:44278
Mus musculus PAX5 MGD MGI:97489