2. Gene
  3. THAP4 - THAP domain containing 4 Gene

THAP4 - THAP domain containing 4 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 THAP 域 4

种属: Homo sapiens

同用名: PP238; CGI-36; Nb(III)

基因 ID: 51078 | 基因类型: protein coding

关于 THAP4

Cytogenetic location: 2q37.3 Genomic coordinates (GRCh38): 2:241,584,405-241,637,576 (from NCBI)

This gene has 5 transcripts (splice variants) and 208 orthologues. Ubiquitous expression in testis (RPKM 14.3), heart (RPKM 13.9) and 25 other tissues.

功能概要

启用多种功能，包括血红素结合活动；相同的蛋白质结合活性；和过氧亚硝酸异构酶活性。参与硝酸盐代谢过程和酪氨酸代谢过程。 [由基因组资源联盟提供，2022 年 4 月]

Enables several functions, including heme binding activity; identical protein binding activity; and peroxynitrite isomerase activity. Involved in nitrate metabolic process and tyrosine metabolic process. [provided by Alliance of Genome Resources, Apr 2022]

THAP4 基因产物(2)

mRNA Protein Name
NM_001164356.2 NP_001157828.1 peroxynitrite isomerase THAP4 isoform 2
NM_015963.6 NP_057047.4 peroxynitrite isomerase THAP4 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables heme binding IMP
IMP: 通过突变表型推断
21387410 GOA
enables identical protein binding IPI
IPI: 通过物理相互作用推断
21387410 GOA
enables nitric oxide binding IDA
IDA: 通过直接分析推断
30524950 GOA
enables peroxynitrite isomerase activity IDA
IDA: 通过直接分析推断
30524950 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in nitrate metabolic process IDA
IDA: 通过直接分析推断
30524950 GOA
involved in tyrosine metabolic process IDA
IDA: 通过直接分析推断
30524950 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

THAP4 蛋白结构

THAP

THAP: THAP domain (4 - 90)

DUF1794

DUF1794: Domain of unknown function (DUF1794) (421 - 575)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 577 a.a.
蛋白主名 其他名称

peroxynitrite isomerase THAP4

THAP domain-containing protein 4

THAP4 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra THAP4 Q8WY91 TNFRSF10D Homo sapiens Q9UBN6
Y2H Prey Pooling
32296183
Intra THAP4 Q8WY91 TNFRSF10D Homo sapiens Q9UBN6
Y2H Array
32296183
Intra THAP4 Q8WY91 TNFRSF10D Homo sapiens Q9UBN6
Validated Y2H
32296183
Intra THAP4 Q8WY91 AGTRAP Homo sapiens Q6RW13-2
Y2H Prey Pooling
32296183
Intra THAP4 Q8WY91 AGTRAP Homo sapiens Q6RW13-2
Y2H Array
32296183
Intra THAP4 Q8WY91 CMTM5 Homo sapiens Q96DZ9-2
Y2H Prey Pooling
32296183
Intra THAP4 Q8WY91 CMTM5 Homo sapiens Q96DZ9-2
Validated Y2H
32296183
Intra THAP4 Q8WY91 CMTM5 Homo sapiens Q96DZ9-2
Y2H Array
32296183
Intra THAP4 Q8WY91 AIG1 Homo sapiens Q9NVV5-2
Validated Y2H
32296183
Intra THAP4 Q8WY91 NDRG4 Homo sapiens Q9ULP0-2
Validated Y2H
32296183
Intra THAP4 Q8WY91 LPAR3 Homo sapiens Q9UBY5
Validated Y2H
32296183
Intra THAP4 Q8WY91 TPD52 Homo sapiens P55327-2
Y2H Array
32296183
Intra THAP4 Q8WY91 TPD52 Homo sapiens P55327-2
Y2H Prey Pooling
32296183
Intra THAP4 Q8WY91 DGAT2L6 Homo sapiens Q6ZPD8
Y2H Array
32296183
Intra THAP4 Q8WY91 DGAT2L6 Homo sapiens Q6ZPD8
Y2H Prey Pooling
32296183
Intra THAP4 Q8WY91 RMDN2 Homo sapiens Q96LZ7
Validated Y2H
32296183
Intra THAP4 Q8WY91 CMTM7 Homo sapiens Q96FZ5
Validated Y2H
32296183
Intra THAP4 Q8WY91 TMEM60 Homo sapiens Q9H2L4
Validated Y2H
32296183
Intra THAP4 Q8WY91 FKBP7 Homo sapiens Q9Y680
Y2H Prey Pooling
32296183
Intra THAP4 Q8WY91 FKBP7 Homo sapiens Q9Y680
Y2H Array
32296183
Intra THAP4 Q8WY91 FKBP7 Homo sapiens Q9Y680
Validated Y2H
32296183
Intra THAP4 Q8WY91 CPNE2 Homo sapiens Q96FN4
Anti Tag CoIP
33961781
Intra THAP4 Q8WY91 CPNE2 Homo sapiens Q96FN4
Validated Y2H
32296183
Intra THAP4 Q8WY91 YIPF6 Homo sapiens Q96EC8
Validated Y2H
32296183
Intra THAP4 Q8WY91 BSND Homo sapiens Q8WZ55
Y2H Prey Pooling
32296183
Intra THAP4 Q8WY91 BSND Homo sapiens Q8WZ55
Validated Y2H
32296183
Intra THAP4 Q8WY91 BSND Homo sapiens Q8WZ55
Y2H Array
32296183
Intra THAP4 Q8WY91 SYP Homo sapiens P08247
Y2H Array
32296183
Intra THAP4 Q8WY91 SYP Homo sapiens P08247
Y2H Prey Pooling
32296183
Intra THAP4 Q8WY91 MAL2 Homo sapiens Q969L2
Y2H Prey Pooling
32296183
Intra THAP4 Q8WY91 MAL2 Homo sapiens Q969L2
Y2H Array
32296183
Intra THAP4 Q8WY91 MAL2 Homo sapiens Q969L2
Validated Y2H
32296183
Intra THAP4 Q8WY91 SCAMP1 Homo sapiens O15126
Y2H Array
32296183
Intra THAP4 Q8WY91 SCAMP1 Homo sapiens O15126
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Venous Hemangioma
Chromosome 2q37 Deletion Syndrome

Albright Hereditary Osteodystrophy-Like Syndrome

2q37 Microdeletion Syndrome

Brachydactyly-Intellectual Disability Syndrome

Deletion 2q37

2q37 Deletion Syndrome

Brachydactyly-Mental Retardation Syndrome

Bdmr

Albright Hereditary Osteodystrophy Type 3

Del(2)(Q37)

Monosomy 2q37qter

Albright'S Hereditary Osteodystrophy-Like Syndrome

Monosomy 2q37

Chromosome Deletion Syndrome 2q37
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14475 THAP4 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta THAP4 VGNC VGNC:99410
Mus musculus THAP4 MGD MGI:1914276
Felis catus THAP4 VGNC VGNC:80379
Rattus norvegicus THAP4 RGD RGD:1359473
Canis familiaris THAP4 VGNC VGNC:59098
Bos taurus THAP4 VGNC VGNC:55691
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