1. Gene
  2. RAD51 - RAD51 recombinase Gene

RAD51 - RAD51 recombinase Gene

中文名称:RAD51 重组酶

种属: Homo sapiens

同用名: RECA; BRCC5; FANCR; MRMV2; HRAD51; RAD51A; HsRad51; HsT16930

基因 ID: 5888 | 基因类型: protein coding

关于 RAD51

Cytogenetic location: 15q15.1 Genomic coordinates (GRCh38): 15:40,694,733-40,732,340 (from NCBI)

This gene has 11 transcripts (splice variants), 220 orthologues, 6 paralogues and is associated with 7 phenotypes. Biased expression in testis (RPKM 6.6), bone marrow (RPKM 3.5) and 13 other tissues.

功能概要

该基因编码的蛋白质是 RAD51 蛋白质家族的成员。 RAD51 家族成员与细菌 RecA 和酿酒酵母 RAD51 高度相似,并且已知参与 DNA 的同源重组和修复。该蛋白可与 ssDNA 结合蛋白 RPA 和 RAD52 相互作用,被认为在 DNA 的同源配对和链转移中发挥作用。还发现这种蛋白质与 BRCA1 和 BRCA2 相互作用,这可能对细胞对 DNA 损伤的反应很重要。 BRCA2 显示可调节该蛋白质的细胞内定位和 DNA 结合能力。 BRCA2 失活后失去这些控制可能是导致基因组不稳定和肿瘤发生的关键事件。已发现该基因编码不同异构体的多个转录变体。[RefSeq 提供,2009 年 8 月]

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to Bacterial RecA and Saccharomyces cerevisiae RAD51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]

RAD51 基因产物(10)

mRNA Protein Name
NM_001164269.2 NP_001157741.1 DNA repair protein RAD51 homolog 1 isoform 2
XM_011521857.3 XP_011520159.2 DNA repair protein RAD51 homolog 1 isoform X1
NM_001164270.2 NP_001157742.1 DNA repair protein RAD51 homolog 1 isoform 3
XM_011521860.3 XP_011520162.1 DNA repair protein RAD51 homolog 1 isoform X2
NM_002875.5 NP_002866.2 DNA repair protein RAD51 homolog 1 isoform 1
XM_047432925.1 XP_047288881.1 DNA repair protein RAD51 homolog 1 isoform X4
XM_011521861.3 XP_011520163.2 DNA repair protein RAD51 homolog 1 isoform X3
NM_133487.4 NP_597994.3 DNA repair protein RAD51 homolog 1 isoform 2
XM_011521859.3 XP_011520161.1 DNA repair protein RAD51 homolog 1 isoform X2
XM_011521858.3 XP_011520160.1 DNA repair protein RAD51 homolog 1 isoform X2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP binding IDA
IDA: 通过直接分析推断
16428451 GOA
enables DNA polymerase binding IPI
IPI: 通过物理相互作用推断
19995904 GOA
enables DNA strand exchange activity IDA
IDA: 通过直接分析推断
18417535 GOA
enables chromatin binding IDA
IDA: 通过直接分析推断
23401855 GOA
enables double-stranded DNA binding IDA
IDA: 通过直接分析推断
7988572 GOA
enables double-stranded DNA binding IMP
IMP: 通过突变表型推断
26681308 GOA
enables enzyme binding IPI
IPI: 通过物理相互作用推断
23401855 GOA
enables identical protein binding IPI
IPI: 通过物理相互作用推断
9396801 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
8675009 GOA
enables single-stranded DNA binding IDA
IDA: 通过直接分析推断
7988572 GOA
enables single-stranded DNA binding IMP
IMP: 通过突变表型推断
26681308 GOA
enables single-stranded DNA helicase activity IDA
IDA: 通过直接分析推断
7988572 GOA
enables single-stranded DNA helicase activity IMP
IMP: 通过突变表型推断
26681308 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in DNA damage response IDA
IDA: 通过直接分析推断
17996710 GOA
involved in DNA damage response IMP
IMP: 通过突变表型推断
26681308 GOA
involved in DNA recombinase assembly IMP
IMP: 通过突变表型推断
26681308 GOA
involved in DNA unwinding involved in DNA replication IDA
IDA: 通过直接分析推断
7988572 GOA
involved in cellular response to camptothecin IDA
IDA: 通过直接分析推断
23509288 GOA
involved in cellular response to ionizing radiation IDA
IDA: 通过直接分析推断
23509288 GOA
involved in cellular response to ionizing radiation IMP
IMP: 通过突变表型推断
14636569 GOA
acts upstream of or within double-strand break repair via homologous recombination IDA
IDA: 通过直接分析推断
16428451 GOA
involved in double-strand break repair via homologous recombination IDA
IDA: 通过直接分析推断
17996710 GOA
involved in double-strand break repair via homologous recombination IMP
IMP: 通过突变表型推断
22778135 GOA
involved in interstrand cross-link repair IMP
IMP: 通过突变表型推断
26253028 GOA
involved in positive regulation of DNA ligation IDA
IDA: 通过直接分析推断
8929543 GOA
involved in regulation of double-strand break repair via homologous recombination IDA
IDA: 通过直接分析推断
23754376 GOA
involved in replication fork processing IDA
IDA: 通过直接分析推断
18417535 GOA
involved in replication fork processing IMP
IMP: 通过突变表型推断
22778135 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in PML body IDA
IDA: 通过直接分析推断
11309417 GOA
located in chromatin IDA
IDA: 通过直接分析推断
25585578 GOA
located in chromosome, telomeric region IDA
IDA: 通过直接分析推断
21076401 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
16215984 GOA
located in lateral element IDA
IDA: 通过直接分析推断
9774970 GOA
located in mitochondrion IDA
IDA: 通过直接分析推断
20413593 GOA
located in nuclear chromosome IDA
IDA: 通过直接分析推断
23754376 GOA
part of nuclear ubiquitin ligase complex IDA
IDA: 通过直接分析推断
14636569 GOA
located in nucleus IDA
IDA: 通过直接分析推断
12442171 GOA
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
16215984 GOA
is active in presynaptic intermediate filament cytoskeleton IDA
IDA: 通过直接分析推断
18003859 GOA
part of protein-containing complex IDA
IDA: 通过直接分析推断
16990250 GOA
is active in site of double-strand break IDA
IDA: 通过直接分析推断
26811421 GOA
located in site of double-strand break IDA
IDA: 通过直接分析推断
24550317 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

RAD51 蛋白结构

HHH_5

HHH_5: Helix-hairpin-helix domain (31 - 80)

Rad51

Rad51: Rad51 (83 - 338)

  • 0
  • 100
  • 200
  • 300
  • 339 a.a.
蛋白主名 其他名称

DNA repair protein RAD51 homolog 1

BRCA1/BRCA2-containing complex, subunit 5

RAD51 homolog A

RecA, E. coli, homolog of

RecA-like protein

recombination protein A

RAD51 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra RAD51 Q06609 SPIDR Homo sapiens Q14159
Anti Bait CoIP
23509288
Intra RAD51 Q06609 SPIDR Homo sapiens Q14159
Pull Down
23509288
Intra RAD51 Q06609 SPIDR Homo sapiens Q14159
Anti Tag CoIP
23509288
Intra RAD51 Q06609 RAD51AP1 Homo sapiens Q96B01-2
Y2H
9396801
Intra RAD51 Q06609 RAD51AP1 Homo sapiens Q96B01-3
Pull Down
21307306
Intra RAD51 Q06609 RAD51AP1 Homo sapiens Q96B01-3
Pull Down
21903585
Intra RAD51 Q06609 PALB2 Homo sapiens Q86YC2
Pull Down
24141787
Intra RAD51 Q06609 RAD51C Homo sapiens O43502
Anti Bait CoIP
16395335
Intra RAD51 Q06609 XRCC3 Homo sapiens O43542
Y2H
28864920
Intra RAD51 Q06609 BRCA2 Homo sapiens P51587
Pull Down
15800615
Intra RAD51 Q06609 BRCA2 Homo sapiens P51587
Pull Down
17541404
Intra RAD51 Q06609 BRCA2 Homo sapiens P51587
Anti Tag CoIP
15800615
Intra RAD51 Q06609 NSD3 Homo sapiens Q9BZ95
Y2H Array
25640309
Intra RAD51 Q06609 NSD3 Homo sapiens Q9BZ95
Anti Tag CoIP
25640309
Intra RAD51 Q06609 SWSAP1 Homo sapiens Q6NVH7
Pull Down
21965664
Intra RAD51 Q06609 RAD52 Homo sapiens P43351
Anti Tag CoIP
19338310
Intra RAD51 Q06609 RAD52 Homo sapiens P43351
Y2H
12750383
Intra RAD51 Q06609 RAD52 Homo sapiens P43351
Y2H
19338310
Intra RAD51 Q06609 NAT2 Homo sapiens P11245
Y2H Array
25640309
Intra RAD51 Q06609 LRATD2 Homo sapiens Q96KN1
Anti Tag CoIP
25640309
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Werner Syndrome

Werner'S Syndrome

WRN

Adult Progeria

Ws

Adult Premature Ageing Syndrome

Adult Premature Aging Syndrome

Werners Syndrome

Fallopian Tube Disease

Fallopian Tube Diseases

Spastic Paraplegia 84, Autosomal Recessive

SPG84

Hereditary Spastic Paraplegia 84

Spastic Paraplegia 84 Autosomal Recessive

Doid:0112347

Deficiency Anemia

Anemia

Deficiency Anemias

Anaemia

Fanconi Anemia, Complementation Group A

Fanconi Anemia

Fanconi Pancytopenia

Fanconi Anemia Complementation Group A

FANCA

Fa

Fanconi Panmyelopathy

Fanconi'S Anemia

Fanconi Anaemia

Fanconi'S Anaemia

Fanconi Hypoplastic Anemia

Estren-Dameshek Variant Of Fanconi Anemia

Estren-Dameshek Variant Of Fanconi Pancytopenia

Fanconi Anemia Estren-Dameshek Variant

Fanconis Anemia

Endometrial Cancer

Endometrial Carcinoma

Endometrial Neoplasm

Malignant Neoplasm Of Endometrium

Endometrioid Carcinoma

Endometrial Neoplasms

Carcinoma, Endometrioid

Endometrial Cancer, Familial

Endometrial Carcinoma, Somatic

Endometrial Cancer, Susceptibility To

Endometrial Ca

Malignant Endometrial Neoplasm

Neoplasm Of Endometrium

Primary Malignant Neoplasm Of Endometrium

Tumor Of Endometrium

Carcinoma Of The Endometrium

Endometrioid Carcinoma Of Female Reproductive System

ENDMC

Carcinoma Endometrioid

Endometrial Cancers

Cancer, Endometrial

Uterine Corpus Cancer

Microcephaly

Microencephaly

Microcephalus

Microcephalic

Nanocephaly

Congenital Microcephaly

Brain Hypoplasia

Brain Nondevelopment

Cephalic Hypoplasia

Undeveloped Cerebrum

Undeveloped Brain

Micrencephalon

Micrencephaly

Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon

Pontocerebellar Hypoplasia, Type 2e

Pontocerebellar Hypoplasia Type 2

Pontocerebellar Hypoplasia Type 2e

Pch2

PCH2E

Progressive Microcephaly From Birth Extrapyramidal Dyskinesia Chorea Epilepsy

Pontocerebellar Hypoplasia 2e

Pcca2

Progressive Cerebello-Cerebral Atrophy Type 2

Doid:0112328

Hypoplasia, Pontocerebellar, Type 2e

Pontocerebellar Hypoplasia, Type 2d

Pontocerebellar Hypoplasia Type 2a

Immunodeficiency 25

Immunodeficiency Due To Defect In Cd3-Zeta

IMD25

Immunodeficiency, Type 25

Autosomal Recessive Cerebellar Ataxia

Arca

Alternating Hemiplegia Of Childhood

Alternating Hemiplegia

Ahc

Alternating Hemiplegia Syndrome

Hemiplegia, Alternating, Of Childhood

Hemiplegia, Crossed

Spastic Paraplegia 85, Autosomal Recessive

SPG85

Hereditary Spastic Paraplegia 85

Spastic Paraplegia 85 Autosomal Recessive

Doid:0112345

Sporadic Breast Cancer

Sporadic Breast Carcinoma

Pontocerebellar Hypoplasia

Pch

Congenital Pontocerebellar Hypoplasia

Opch

Hypoplasia, Pontocerebellar

Pontoneocerebellar Hypoplasia

Nonsyndromic Pontocerebellar Hypoplasia

Spastic Paraplegia 86, Autosomal Recessive

SPG86

Hereditary Spastic Paraplegia 86

Spastic Paraplegia 86 Autosomal Recessive

Doid:0112342

Li-Fraumeni Syndrome

Sarcoma Family Syndrome Of Li And Fraumeni

Sbla Syndrome

LFS

Li-Fraumeni Familiar Cancer Susceptibility Syndrome

Sarcoma, Breast, Leukaemia And Adrenal Gland Syndrome

Lfs1

Li Fraumeni Syndrome

Sarcoma, Breast, Leukemia, And Adrenal Gland Syndrome

Lfl

Sbla Syndrome Li-Fraumeni-Like Syndrome

Li-Fraumeni Syndrome 1

Fanconi Anemia, Complementation Group R

Fanconi Anemia Complementation Group R

FANCR

Hereditary Breast Ovarian Cancer Syndrome

Hereditary Breast And Ovarian Cancer Syndrome

Brca1- And Brca2-Associated Hereditary Breast And Ovarian Cancer

Breast And/Or Ovarian Cancer

Breast And Ovarian Cancer Syndrome

Hboc Syndrome

Hereditary Breast And Ovarian Cancer

Brca1- Brca2-Associated Hboc

Neuroma
Bloom Syndrome

BLM

Bs

Bls

Bloom-Torre-Machacek Syndrome

Microcephaly, Growth Restriction, And Increased Sister Chromatid Exchange 1

Mgrisce1

Congenital Telangiectatic Erythema

Congenital Telangiectatic Erythema Syndrome

Growth Deficiency, Sun-Sensitive, Telangiectatic, Hypo And Hyperpigmented Skin, Predisposition To Malignancy And Chromosomal Instability

Bloom'S Syndrome

Bsyn

Fanconi Anemia, Complementation Group D2

Fanconi Anemia Complementation Group D2

FANCD2

Fad2

Fa4

Fancd

Fanconi Pancytopenia Type 4

Fanconi Anemia, Complementation Group D

Fanconi Pancytopenia, Type 4

Facd

Fanconi Anemia Complementation Group D

Haverhill Fever

Streptobacillosis

Streptobacillary Rat-Bite Fever

Streptobacillary Fever

Rat-Bite Fever Due To Streptobacillus Moniliformis

Erythema Arthriticum Epidemicum

Epidemic Arthritic Erythema

Physical Disorder

Physical Illness

Aplastic Anemia

Aplastic Anemia, Susceptibility To

Anemia Aplastic

Idiopathic Aplastic Anemia

Secondary Aplastic Anemia

Idiopathic Bone Marrow Failure

Aplastic Anemia Idiopathic

AA

Anemia, Aplastic

Aplastic Anemia, Idiopathic

Erythroid Aplasia

Aa - [Aplastic Anaemia]

Haematopoietic Aplasia

Aleukia Haemorrhagica

Anaemia Due To Decreased Red Cell Production

Aplasia Bone Marrow

Aplastic Bone Marrow

Hypoplastic Anaemia Nos

Myeloid Bone Marrow Aplasia

Pancytopenia

Panhaematopenia

Hypoproliferative Anaemia

Medullary Hypoplasia

Red Blood Cells Hypoplastic Anaemia

Panmyelophthisis

Panhemocytopenia

Refractive Hypoproliferative Anaemia

Toxic Anaemia

Toxic Aplastic Anaemia

Aplastic Anaemia Due To Toxic Cause

Idiopathic Aplastic Anaemia Nos

Rothmund-Thomson Syndrome, Type 2

Rothmund-Thomson Syndrome

Rts

RTS2

Poikiloderma Of Rothmund-Thomson

Rothmund-Thomson Syndrome Type 2

Congenital Poikiloderma

Poikiloderma Congenitale

Poikiloderma Atrophicans And Cataract

Poikiloderma Congenitale Of Rothmund-Thomson

Poikiloderma Of Rothmund-Thomson Type 2

Rothmund-Thomson Syndrome 2

Erythrokeratodermia Variabilis

Trichohepatoenteric Syndrome 1

Trichohepatoenteric Syndrome

Syndromic Diarrhea

Tricho-Hepato-Enteric Syndrome

Sd/The

Syndromic Diarrhea/Tricho-Hepato-Enteric Syndrome

THES1

Phenotypic Diarrhea

Thes

Phenotypic Diarrhea Of Infancy

Diarrhea, Syndromic

Diarrhea, Fatal Infantile, With Trichorrhexis Nodosa

Intractable Diarrhea With Phenotypic Anomalies

Syndromatic Diarrhea

Fatal Infantile Diarrhea With Trichorrhexis Nodosa

Xeroderma Pigmentosum, Variant Type

Xeroderma Pigmentosum

XPV

Xeroderma Pigmentosum Variant Type

Xeroderma Pigmentosum With Normal Dna Repair Rates

Photosensitivity With Defective Dna Synthesis

De Sanctis-Cacchione Syndrome

Xp

Desanctis-Cacchione Syndrome

Xeroderma Pigmentosa

Xerodermic Idiocy

Xeroderma Pigmentosum Variant

Xp - [Xeroderma Pigmentosum]

Atrophoderma Pigmentosum

Leukemia, Acute Myeloid

Acute Myeloid Leukemia

Leukemia, Acute Myelogenous

Acute Myelogenous Leukemia

AML

Leukemia, Acute Myeloid, Susceptibility To

Acute Myeloblastic Leukemia

Leukemia, Acute Myeloid, Reduced Survival In, Somatic

Acute Myeloid Leukaemia

Leukemia, Myelocytic, Acute

Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome

Secondary Aml

Acute Myelocytic Leukemia

Leukemia, Myeloid, Acute

Acute Myeloid Leukemia, Somatic

Leukemia, Acute Myeloid, Somatic

Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic

Acute Myeloblastic Leukaemia

Acute Myelogenous Leukaemia

Aml - Acute Myeloid Leukemia

Acute Myeloid Leukemia With Cebpa Somatic Mutations

Aml With Cebpa Somatic Mutations

Inherited Acute Myeloid Leukemia

Familial Aml

Inherited Aml

Pure Familial Aml

Pure Familial Acute Myeloid Leukemia

Secondary Acute Myeloid Leukemia

Therapy-Related Aml And Myelodysplastic Syndrome

Acute Myeloid Leukemia, Secondary

Acute Non-Lymphoblastic Leukemia

Acute Non-Lymphocytic Leukemia

Acute Biphenotypic Leukemia

Acute Undifferentiated Leukemia

Acute Myeloblastic Leukaemia With Multilineage Dysplasia

Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission

Acute Myeloid Leukaemia With Myelodysplasia-Related Features

Glanders

Farcy Pipes

Infection Due To Pseudomonas Mallei

Burkholderia Mallei

Burkholderia Mallei Infection

Equina

Equine Glanders

Farcy

Farcy Buds

Farcy Cords

Infection Due To Actinobacillus Mallei

Infection Due To Malleomyces Mallei

Maliasmus

Malleus

Farce

Actinobacillosis

Actinobacillus Infection

Ataxia-Telangiectasia

Ataxia Telangiectasia

Louis-Bar Syndrome

AT

At1

Ataxia-Telangiectasia Syndrome

Ataxia - Telangiectasia Variant

Boder-Sedgwick Syndrome

Louis Bar Syndrome

Cerebello-Oculocutaneous Telangiectasia

Immunodeficiency With Ataxia Telangiectasia

A-T

Ataxia Telangiectasia Syndrome

Atm

Telangiectasia, Cerebello-Oculocutaneous

Ataxia-Telangiectasia Variant

Breast Cancer

Breast Carcinoma

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Male Breast Cancer

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation

Lynch Syndrome

Hereditary Nonpolyposis Colon Cancer

Hereditary Nonpolyposis Colorectal Cancer

Hereditary Nonpolyposis Colorectal Carcinoma

Hereditary Nonpolyposis Colorectal Neoplasms

Familial Nonpolyposis Colon Cancer

Hnpcc

Coca 1

Hereditary Defective Mismatch Repair Syndrome

Hereditary Non-Polyposis Colon Cancer

Hereditary Non-Polyposis Colon Cancer Syndrome

Hereditary Non-Polyposis Colorectal Cancer

Hereditary Non-Polyposis Colorectal Cancer Syndrome

Hereditary Nonpolyposis Colon Cancer Syndrome

Hereditary Nonpolyposis Colorectal Cancer Syndrome

Hereditary Nonpolyposis Colorectal Neoplasm

Hnpcc - Hereditary Nonpolyposis Colon Cancer

Cancer Family Syndrome

Familial Nonpolyposis Colorectal Cancer

Colon Cancer, Familial Nonpolyposis

Colorectal Neoplasms, Hereditary Nonpolyposis

Cancer, Colorectal, Nonpolyposis, Hereditary

Colorectal Cancer, Hereditary Nonpolyposis, Type 1

Fanconi Anemia, Complementation Group D1

Fanconi Anemia Complementation Group D1

FANCD1

Fad1

Inherited Cancer-Predisposing Syndrome Due To Biallelic Brca2 Mutations

Cerebellar Disease

Cerebellar Diseases

Cerebellar Dysfunction

Cerebellar Abnormality

Cerebellar Disorders

Mirror Movements 1

Congenital Mirror Movement Disorder

Bimanual Synergia

Congenital Mirror Movements

Familial Congenital Controlateral Synkinesia

Familial Congenital Mirror Movements

Hereditary Congenital Controlateral Synkinesia

Hereditary Congenital Mirror Movements

Isolated Congenital Controlateral Synkinesia

Isolated Congenital Mirror Movements

Mirror Movements

MRMV1

Mirror Movements 1 And/Or Agenesis Of The Corpus Callosum

Mirror Movements, Congenital

Bimanual Synkinesis

Cmm

Mirror Movements, Type 1

Trichothiodystrophy

Ttd

Amish Brittle Hair Syndrome

Bids Syndrome

Brittle Hair-Intellectual Impairment-Decreased Fertility-Short Stature Syndrome

Ibids

Pibids

Trichothiodystrophy Syndromes

Nijmegen Breakage Syndrome

Berlin Breakage Syndrome

NBS

Microcephaly, Normal Intelligence And Immunodeficiency

Ataxia-Telangiectasia Variant

Ataxia-Telangiectasia Variant V1

Seemanova Syndrome Ii

Immunodeficiency-Microcephaly-Chromosomal Instability Syndrome

Seemanova Syndrome Type 2

At-V1

Microcephaly With Normal Intelligence, Immunodeficiency, And Lymphoreticular Malignancies

Nonsyndromal Microcephaly, Autosomal Recessive, With Normal Intelligence

Immunodeficiency, Microcephaly, And Chromosomal Instability

Microcephaly-Immunodeficiency-Lymphoreticuloma Syndrome

Microcephaly Immunodeficiency Lymphoreticuloma

Microcephaly With Normal Intelligence Immunodeficiency And Lymphoreticular Malignancies

Nonsyndromal Microcephaly Autosomal Recessive With Normal Intelligence

Seemanova Syndrome 2

Ataxia-Telangiectasia Variant 1

Seemanova Syndrome

At V1

Ataxia-Telangiectasia, Variant 1

Microcephaly-Immunodeficiency-Lymphoid Malignancy Syndrome

V-At

Ataxia Telangiectasia Variant V1

Seckel Syndrome

Microcephalic Primordial Dwarfism

Bird-Headed Dwarfism

Harper'S Syndrome

Virchow-Seckel Dwarfism

Nanocephalic Dwarfism

Sckl

Seckel-Type Dwarfism

Parkinsonism With Spasticity, X-Linked

X-Linked Parkinsonism-Spasticity Syndrome

XPDS

X-Linked Parkinsonism With Spasticity

Cockayne Syndrome A

Cockayne Syndrome Type 1

Cockayne Syndrome, Type A

Cockayne Syndrome Type I

CSA

Cockayne Syndrome Classic Form

Cockayne Syndrome Classical

Cockayne Syndrome Type A

Ckn1

Bilateral Breast Cancer

Bilateral Breast Carcinoma

Medulloblastoma

MDB

Cpnet

Localized Primitive Neuroectodermal Tumor

Classic Medulloblastoma

Desmoplastic/Nodular Medulloblastoma

Medulloblastoma With Extensive Nodularity

Desmoplastic Medulloblastoma

Medulloblastoma, Somatic

Medulloblastoma, Desmoplastic

Brain Medulloblastoma

Cns Pnet

Infratentorial Primitive Neuroectodermal Tumor

Mben

Medulloblastoma Desmoplastic

Neuroectodermal Tumors, Primitive

Medulloblastomas

Medulloblastoma, With Extensive Nodularity

Medulloblastoma Of Unspecified Site

Medullomyoblastoma Of Unspecified Site

Pancreatic Adenocarcinoma

Adenocarcinoma Of Pancreas

Adenocarcinoma Of The Pancreas

Pancreas Adenocarcinoma

Malignant Exocrine Neoplasm

Primary Pancreatic Adenocarcinoma

Adenocarcinoma Of Islet Cell Of Pancreas

Islet Cell Adenocarcinoma Of Unspecified Site

Mixed Adenocarcinoma Islet Cell With Exocrine Of Unspecified Site

Cervix Melanoma
Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer

Ovarian Cancer

Ovarian Carcinoma

Ovarian Neoplasm

Malignant Tumour Of Ovary

Epithelial Ovarian Cancer

Neoplasm Of Ovary

Ovarian Neoplasms

Ovarian Cancers

Malignant Neoplasm Of Ovary

Primary Malignant Neoplasm Of Ovary

Ovarian Cancer, Somatic

Malignant Ovarian Tumor

Ovary Neoplasm

Primary Ovarian Cancer

Tumor Of The Ovary

Cancer Of The Ovary

Malignant Neoplasm Of The Ovary

Malignant Tumor Of The Ovary

Ovarian Malignant Tumor

OC

Ovarian Carcinomas

Cancer, Ovarian

Cancer Of Ovary

Ovary Cancer

Ca Ovary

Congenital Nervous System Abnormality

Congenital Neurologic Anomaly

Congenital Nervous System Disorder

Mirror Movements 2

MRMV2

Mirror Movements, Type 2

Cowden Syndrome

Cowden Disease

Multiple Hamartoma Syndrome

Cowden'S Disease

Lhermitte-Duclos Disease

Cd

Cs

Mham

Dysplastic Gangliocytoma Of Cerebellum

Cowden'S Syndrome

Hamartoma Syndrome, Multiple

Malignant Renovascular Hypertension

Secondary Malignant Renovascular Hypertension

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus RAD51 RGD RGD:1563603
Felis catus RAD51 VGNC VGNC:69215
Macaca mulatta RAD51 VGNC VGNC:76645
Mus musculus RAD51 MGD MGI:97890
Bos taurus RAD51 VGNC VGNC:33684
Canis familiaris RAD51 VGNC VGNC:45317
Others RAD51 NCBI