GIGYF1 - GRB10 interacting GYF protein 1 Gene

中文名称：GRB10 相互作用 GYF 蛋白 1

种属: Homo sapiens

同用名: GYF1; PERQ1

基因 ID: 64599 | 基因类型: protein coding

关于 GIGYF1

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:100,679,507-100,694,250 (from NCBI)

This gene has 7 transcripts (splice variants), 226 orthologues, 1 paralogue and is associated with 1 phenotype. Ubiquitous expression in testis (RPKM 15.6), endometrium (RPKM 14.8) and 25 other tissues.

功能概要

该基因编码 gyf 衔接蛋白家族的一个成员。编码的蛋白质包含一个 gyf 蛋白质相互作用结构域。它结合生长因子受体结合 10，这是另一种结合活化的胰岛素样生长因子 1 和胰岛素受体并调节受体信号传导的衔接蛋白。[RefSeq 提供，2017 年 4 月]

This gene encodes a member of the gyf family of adaptor proteins. The encoded protein contains a gyf protein interaction domain. It binds growth factor receptor bound 10, another adaptor protein that binds activated insulin-like growth factor 1 and Insulin receptors and regulates receptor signaling. [provided by RefSeq, Apr 2017]

GIGYF1 基因产物(10)

mRNA	Protein	Name
NM_001375759.1	NP_001362688.1	GRB10-interacting GYF protein 1 isoform a
NM_001375760.1	NP_001362689.1	GRB10-interacting GYF protein 1 isoform a
NM_001375761.1	NP_001362690.1	GRB10-interacting GYF protein 1 isoform a
NM_001375762.1	NP_001362691.1	GRB10-interacting GYF protein 1 isoform a
NM_001375763.1	NP_001362692.1	GRB10-interacting GYF protein 1 isoform a
NM_001375764.1	NP_001362693.1	GRB10-interacting GYF protein 1 isoform a
NM_001375765.1	NP_001362694.1	GRB10-interacting GYF protein 1 isoform b
NM_001375766.1	NP_001362695.1	GRB10-interacting GYF protein 1 isoform b
NM_001375767.1	NP_001362696.1	GRB10-interacting GYF protein 1 isoform c
NM_001375768.1	NP_001362697.1	GRB10-interacting GYF protein 1 isoform d

GIGYF1 蛋白结构

GYF

0
200
400
600
800
1035 a.a.

蛋白主名

其他名称

GRB10-interacting GYF protein 1

PERQ amino acid-rich with GYF domain-containing protein 1

GIGYF1 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	GIGYF1	O75420	NFKBID	Homo sapiens	Q8NI38	Validated Y2H	32296183
种属内	GIGYF1	O75420	TSHZ2	Homo sapiens	Q9NRE2	Validated Y2H	32296183
种属内	GIGYF1	O75420	CCDC57	Homo sapiens	Q2TAC2-2	Validated Y2H	32296183
种属内	GIGYF1	O75420	TLE5	Homo sapiens	Q08117-2	Validated Y2H	32296183
种属内	GIGYF1	O75420	NEK6	Homo sapiens	Q9HC98-4	Validated Y2H	32296183
种属内	GIGYF1	O75420	SPAG8	Homo sapiens	Q99932-2	Validated Y2H	32296183
种属内	GIGYF1	O75420	PRR35	Homo sapiens	P0CG20	Validated Y2H	32296183
种属内	GIGYF1	O75420	PRR35	Homo sapiens	P0CG20	Y2H Prey Pooling	32296183
种属内	GIGYF1	O75420	FAM124B	Homo sapiens	Q9H5Z6-2	Validated Y2H	32296183
种属内	GIGYF1	O75420	ANKRD10	Homo sapiens	Q9NXR5-2	Validated Y2H	32296183
种属内	GIGYF1	O75420	PRKAA2	Homo sapiens	P54646	Validated Y2H	32296183
种属内	GIGYF1	O75420	KIFC3	Homo sapiens	Q9BVG8-5	Validated Y2H	32296183
种属内	GIGYF1	O75420	TROAP	Homo sapiens	Q12815	Validated Y2H	32296183
种属内	GIGYF1	O75420	RBM22	Homo sapiens	Q9NW64	Validated Y2H	32296183
种属内	GIGYF1	O75420	EIF4E2	Homo sapiens	O60573-1	ITC	28698298
种属内	GIGYF1	O75420	EIF4E2	Homo sapiens	O60573-1	Anti Tag CoIP	28698298
种属内	GIGYF1	O75420	EIF4E2	Homo sapiens	O60573-1	Pull Down	28698298
种属内	GIGYF1	O75420	MCRS1	Homo sapiens	Q96EZ8	Validated Y2H	32296183
种属内	GIGYF1	O75420	DDX6	Homo sapiens	P26196	Anti Tag CoIP	33961781
种属内	GIGYF1	O75420	DDX6	Homo sapiens	P26196	Validated Y2H	32296183
种属内	GIGYF1	O75420	DYNC1H1	Homo sapiens	Q14204	Anti Bait CoIP	36950384
种属内	GIGYF1	O75420	SMARCC2	Homo sapiens	Q8TAQ2	Anti Bait CoIP	36950384
种属内	GIGYF1	O75420	SMARCD1	Homo sapiens	Q96GM5	Validated Y2H	32296183
种属内	GIGYF1	O75420	SNRPB	Homo sapiens	P14678-2	Validated Y2H	32296183
种属内	GIGYF1	O75420	KAT5	Homo sapiens	Q92993	Validated Y2H	32296183
种属内	GIGYF1	O75420	SNRPA	Homo sapiens	P09012	Validated Y2H	32296183
种属内	GIGYF1	O75420	TCEA2	Homo sapiens	Q15560	Validated Y2H	32296183
种属内	GIGYF1	O75420	CBX8	Homo sapiens	Q9HC52	Validated Y2H	32296183
种属内	GIGYF1	O75420	ZNF598	Homo sapiens	Q86UK7	Anti Tag CoIP	33053355
种属内	GIGYF1	O75420	ZNF598	Homo sapiens	Q86UK7	Anti Tag CoIP	33961781
种属内	GIGYF1	O75420	CRACR2A	Homo sapiens	Q9BSW2	Validated Y2H	32296183
种属内	GIGYF1	O75420	ARMC7	Homo sapiens	Q9H6L4	Validated Y2H	32296183
种属内	GIGYF1	O75420	MNS1	Homo sapiens	Q8NEH6	Validated Y2H	32296183
种属内	GIGYF1	O75420	ENKD1	Homo sapiens	Q9H0I2	Validated Y2H	32296183
种属内	GIGYF1	O75420	STAC3	Homo sapiens	Q96MF2	Validated Y2H	32296183
种属内	GIGYF1	O75420	STAC3	Homo sapiens	Q96MF2	Anti Bait CoIP	36950384
种属内	GIGYF1	O75420	SCNM1	Homo sapiens	Q9BWG6	Y2H Prey Pooling	32296183
种属内	GIGYF1	O75420	SCNM1	Homo sapiens	Q9BWG6	Validated Y2H	32296183
种属内	GIGYF1	O75420	SNRPC	Homo sapiens	P09234	Validated Y2H	32296183
种属内	GIGYF1	O75420	SCAF8	Homo sapiens	Q9UPN6	Validated Y2H	32296183
种属内	GIGYF1	O75420	AIRIM	Homo sapiens	Q9NX04	Validated Y2H	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Autism Spectrum Disorder

Asd	Autism Spectrum Disorders
Autistic Continuum	Pervasive Developmental Disorder
Pervasive Development Disorder	Autistic Behavior
Autistic Disorder	Autistic
Autistic Disorder Of Childhood Onset	Infantile Autism
Childhood Autism	Kanner Syndrome
Pervasive Developmental Delay Nos	Pervasive Developmental Disorder, Not Otherwise Specified

Autism

Autistic Disorder	Autism Susceptibility 1
Childhood Autism	Autistic Disorder Of Childhood Onset
Infantile Autism	Kanner'S Syndrome
Autistic

Parkinson Disease, Late-Onset

Parkinson Disease	Parkinson'S Disease
PD	PARK
Parkinson Disease, Susceptibility To	Late Onset Parkinson'S Disease
Late Onset Parkinson Disease	Paralysis Agitans
Primary Parkinsonism	Idiopathic Parkinson Disease
Parkinson'S	Parkinson Disease, Late-Onset, Susceptibility To
Parkinson Disease, Age Of Onset, Modifier	Lewy Body Parkinson Disease
Idiopathic Parkinson'S Disease	Pd - [Parkinson Disease]
Parkinson Disease Nos	Parkinson, Nos
Primary Parkinson Disease

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS05421	GIGYF1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Felis catus	GIGYF1	VGNC	VGNC:68924
Canis familiaris	GIGYF1	VGNC	VGNC:41213
Rattus norvegicus	GIGYF1	RGD	RGD:1309933
Bos taurus	GIGYF1	VGNC	VGNC:29355
Mus musculus	GIGYF1	MGD	MGI:1888677
Macaca mulatta	GIGYF1	VGNC	VGNC:73158

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

GIGYF1 - GRB10 interacting GYF protein 1 Gene

关于 GIGYF1

功能概要

GIGYF1 基因产物(10)

GIGYF1 蛋白结构

GIGYF1 蛋白互作信息

关联疾病

直系同源

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GIGYF1 - GRB10 interacting GYF protein 1 Gene

关于 GIGYF1

功能概要

GIGYF1 基因产物(10)

GIGYF1 蛋白结构

GIGYF1 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z