2. Gene
  3. Jam2 - junction adhesion molecule 2 Gene

Jam2 - junction adhesion molecule 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: JAM-2; JAM-B; Jcam2; VE-JAM; 1110002N23Rik; 2410030G21Rik; 2410167M24Rik

基因 ID: 67374 | 基因类型: protein coding

关于 Jam2

功能概要

Predicted to enable Integrin binding activity. Involved in several processes, including hematopoietic stem cell migration to bone marrow; leukocyte tethering or rolling; and negative regulation of myelination. Acts upstream of or within negative regulation of cell adhesion. Located in cell surface; somatodendritic compartment; and tight junction. Is expressed in several structures, including alimentary system; brain; cardiovascular system; eye; and genitourinary system. Human ortholog(s) of this gene implicated in basal ganglia calcification. Orthologous to human JAM2 (junctional adhesion molecule 2). [provided by Alliance of Genome Resources, Apr 2022]

Jam2 基因产物(1)

mRNA Protein Name
NM_023844.5 NP_076333.3 junctional adhesion molecule B precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16093349 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell-cell adhesion IMP
IMP: 通过突变表型推断
24357068 MGI
involved in cellular extravasation IDA
IDA: 通过直接分析推断
12239159 MGI
involved in hematopoietic stem cell migration to bone marrow IMP
IMP: 通过突变表型推断
24357068 MGI
involved in leukocyte tethering or rolling IDA
IDA: 通过直接分析推断
19740376 MGI
acts upstream of or within negative regulation of cell adhesion IGI
IGI: 通过遗传相互作用推断
16093349 MGI
involved in negative regulation of myelination IMP
IMP: 通过突变表型推断
27499083 MGI
involved in positive regulation of lymphocyte migration IMP
IMP: 通过突变表型推断
12239159 MGI
involved in spermatid development IDA
IDA: 通过直接分析推断
15372036 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
NOT located in axon IDA
IDA: 通过直接分析推断
27499083 MGI
located in cell surface IDA
IDA: 通过直接分析推断
12239159 MGI
located in somatodendritic compartment IDA
IDA: 通过直接分析推断
27499083 MGI
located in tight junction IDA
IDA: 通过直接分析推断
15372036 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

junctional adhesion molecule B

junction adhesion molecule B

junction cell adhesion molecule 2

junctional adhesion molecule 2

vascular endothelial junction-associated molecule

重组 Jam2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73259 JAM-B/CD322 Protein, Mouse (HEK293, Fc) Q9JI59 (F29-N236) ≥95%
HY-P73260 JAM-B/CD322 Protein, Mouse (HEK293, His) Q9JI59 (F29-N236) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07027 JAM2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS07028 JAM3 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS18768 Jam2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS25256 Jam2 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Jam2 NCBI NCBI:58494
Rattus norvegicus Jam2 NCBI NCBI:619374
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