UBE2V2 - ubiquitin conjugating enzyme E2 V2 Gene

中文名称：泛素结合酶 E2 V2

种属: Homo sapiens

同用名: MMS2; UEV2; EDPF1; UEV-2; DDVIT1; EDAF-1; EDPF-1; DDVit-1

关于 UBE2V2

功能概要

泛素结合酶 E2 变体蛋白构成了 E2 蛋白家族中的一个独特亚家族。它们与其他泛素结合酶具有序列相似性，但缺少对 E2 的催化活性至关重要的保守半胱氨酸残基。该基因编码的蛋白质还与泛素结合酶 E2 变体 1 和酵母 MMS2 基因产物具有同源性。它可能参与单核细胞和肠细胞的分化。[RefSeq 提供，2008 年 7 月]

Ubiquitin-conjugating Enzyme E2 variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to Other ubiquitin-conjugating Enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene also shares homology with ubiquitin-conjugating Enzyme E2 variant 1 and yeast MMS2 gene product. It may be involved in the differentiation of monocytes and enterocytes. [provided by RefSeq, Jul 2008]