1. Gene
  2. UBTD1 - ubiquitin domain containing 1 Gene

UBTD1 - ubiquitin domain containing 1 Gene

中文名称:含泛素结构域 1

种属: Homo sapiens

基因 ID: 80019 | 基因类型: protein coding

关于 UBTD1

Cytogenetic location: 10q24.1-q24.2 Genomic coordinates (GRCh38): 10:97,498,924-97,571,206 (from NCBI)

This gene has 1 transcript (splice variant), 264 orthologues and 1 paralogue. Broad expression in testis (RPKM 17.5), lung (RPKM 11.7) and 22 other tissues.

功能概要

许多蛋白质的降解是通过泛素途径进行的,在该途径中,蛋白质通过多肽泛素的共价缀合被靶向降解。该基因编码一种属于泛素蛋白家族的蛋白质。编码的蛋白质被认为可以调节属于 UBE2D 家族的 E2 泛素结合酶。[RefSeq 提供,2014 年 3 月]

The degradation of many proteins is carried out by the ubiquitin pathway in which proteins are targeted for degradation by covalent conjugation of the polypeptide ubiquitin. This gene encodes a protein that belongs to the ubiquitin family of proteins. The encoded protein is thought to regulate E2 ubiquitin conjugating Enzymes belonging to the UBE2D family. [provided by RefSeq, Mar 2014]

UBTD1 基因产物(1)

mRNA Protein Name
NM_024954.5 NP_079230.1 ubiquitin domain-containing protein 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

UBTD1 蛋白结构

ubiquitin

ubiquitin: Ubiquitin family (155 - 221)

  • 0
  • 100
  • 200
  • 227 a.a.
蛋白主名 其他名称

ubiquitin domain-containing protein 1

UBTD1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra UBTD1 Q9HAC8 TRIM39 Homo sapiens Q9HCM9-2
Y2H Prey Pooling
32296183
Intra UBTD1 Q9HAC8 TRIM39 Homo sapiens Q9HCM9-2
Validated Y2H
32296183
Intra UBTD1 Q9HAC8 TRIM39 Homo sapiens Q9HCM9-2
Y2H Array
32296183
Intra UBTD1 Q9HAC8 TP53BP2 Homo sapiens Q05BL1
Y2H Array
32296183
Intra UBTD1 Q9HAC8 TP53BP2 Homo sapiens Q05BL1
Y2H Prey Pooling
32296183
Intra UBTD1 Q9HAC8 MID1 Homo sapiens O15344
Y2H Array
32296183
Intra UBTD1 Q9HAC8 MID1 Homo sapiens O15344
Y2H Prey Pooling
32296183
Intra UBTD1 Q9HAC8 UBE2D2 Homo sapiens P62837
Anti Tag CoIP
33961781
Intra UBTD1 Q9HAC8 UBE2D3 Homo sapiens P61077
Y2H Array
32296183
Intra UBTD1 Q9HAC8 UBE2D3 Homo sapiens P61077
Y2H Prey Pooling
32296183
Intra UBTD1 Q9HAC8 RNF5 Homo sapiens Q99942
Y2H Array
32296183
Intra UBTD1 Q9HAC8 RNF5 Homo sapiens Q99942
Y2H Prey Pooling
32296183
Intra UBTD1 Q9HAC8 TRAF6 Homo sapiens Q9Y4K3
Y2H Prey Pooling
32296183
Intra UBTD1 Q9HAC8 TRAF6 Homo sapiens Q9Y4K3
Validated Y2H
32296183
Intra UBTD1 Q9HAC8 TRAF6 Homo sapiens Q9Y4K3
Y2H Array
32296183
Intra UBTD1 Q9HAC8 TRIM39 Homo sapiens Q9HCM9
Validated Y2H
25416956
Intra UBTD1 Q9HAC8 TRIM39 Homo sapiens Q9HCM9
Y2H Array
25416956
Intra UBTD1 Q9HAC8 WWP2 Homo sapiens O00308
Y2H Prey Pooling
32296183
Intra UBTD1 Q9HAC8 WWP2 Homo sapiens O00308
Y2H Array
32296183
Intra UBTD1 Q9HAC8 UBE2D4 Homo sapiens Q9Y2X8
Y2H Prey Pooling
32296183
Intra UBTD1 Q9HAC8 UBE2D4 Homo sapiens Q9Y2X8
Y2H
19549727
Intra UBTD1 Q9HAC8 UBE2D4 Homo sapiens Q9Y2X8
Validated Y2H
32296183
Intra UBTD1 Q9HAC8 UBE2D4 Homo sapiens Q9Y2X8
Y2H Array
32296183
Intra UBTD1 Q9HAC8 MRFAP1L1 Homo sapiens Q96HT8
Y2H Array
32296183
Intra UBTD1 Q9HAC8 MRFAP1L1 Homo sapiens Q96HT8
Y2H Prey Pooling
25416956
Intra UBTD1 Q9HAC8 MRFAP1L1 Homo sapiens Q96HT8
Y2H Prey Pooling
32296183
Intra UBTD1 Q9HAC8 MRFAP1L1 Homo sapiens Q96HT8
Validated Y2H
25416956
Intra UBTD1 Q9HAC8 MRFAP1L1 Homo sapiens Q96HT8
Y2H Array
25416956
Intra UBTD1 Q9HAC8 TRIM50 Homo sapiens Q86XT4
Y2H Prey Pooling
32296183
Intra UBTD1 Q9HAC8 TRIM50 Homo sapiens Q86XT4
Y2H Array
32296183
Intra UBTD1 Q9HAC8 MRFAP1 Homo sapiens Q9Y605
Validated Y2H
32296183
Intra UBTD1 Q9HAC8 MRFAP1 Homo sapiens Q9Y605
Y2H Array
32296183
Intra UBTD1 Q9HAC8 MRFAP1 Homo sapiens Q9Y605
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Mus musculus UBTD1 MGD MGI:2385092
Rattus norvegicus UBTD1 RGD RGD:1308172
Canis familiaris UBTD1 VGNC VGNC:48093
Bos taurus UBTD1 VGNC VGNC:36620
Macaca mulatta UBTD1 VGNC VGNC:106114
Felis catus UBTD1 VGNC VGNC:66789