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  2. Cdk16 - cyclin-dependent kinase 16 Gene

Cdk16 - cyclin-dependent kinase 16 Gene

中文名称:细胞周期蛋白依赖性激酶 16

种属: Rattus norvegicus

同用名: Pctk1

基因 ID: 81741 | 基因类型: protein coding

关于 Cdk16

Primary_assembly X: 1,492,814-1,504,148 reverse strand.mRatBN7.2:CM026994.1

This gene has 2 transcripts (splice variants), 174 orthologues, 24 paralogues and is associated with 5 phenotypes. Biased expression in Brain (RPKM 87.6), Heart (RPKM 84.3) and 9 other tissues.

功能概要

该基因编码的蛋白可启动蛋白质丝氨酸/苏氨酸激酶活性。预计将参与多个过程,包括参与细胞对葡萄糖刺激反应的胰岛素分泌调节;参与有丝分裂细胞周期 G1/S 转换的转录调节;和细胞分泌。位于突触小泡。与人 CDK16(细胞周期蛋白依赖性激酶 16)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables protein serine/threonine kinase activity. Predicted to be involved in several processes, including regulation of Insulin secretion involved in cellular response to glucose stimulus; regulation of transcription involved in G1/S transition of mitotic cell cycle; and secretion by cell. Located in synaptic vesicle. Orthologous to human CDK16 (cyclin dependent kinase 16). [provided by Alliance of Genome Resources, Apr 2022]

Cdk16 基因产物(2)

mRNA Protein Name
NM_001004132.2 NP_001004132.1 cyclin-dependent kinase 16
NM_031077.2 NP_112339.2 cyclin-dependent kinase 16
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
16461345 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in synaptic vesicle IDA
IDA: 通过直接分析推断
16461345 RGD
is active in synaptic vesicle membrane IDA
IDA: 通过直接分析推断
16461345 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Cdk16 蛋白结构

STKc_PCTAIRE1

STKc_PCTAIRE1: cd07873 (243 - 539)

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  • 578 a.a.
蛋白主名 其他名称

cyclin-dependent kinase 16

PCTAIRE protein kinase 1

PCTAIRE-1 protein kinase, alternatively spliced

PCTAIRE-motif protein kinase 1

cell division protein kinase 16

serine/threonine-protein kinase PCTAIRE-1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cdk16 NCBI NCBI:5127