2. Gene
  3. Ndel1 - nudE neurodevelopment protein 1 like 1 Gene

Ndel1 - nudE neurodevelopment protein 1 like 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: NUDEL; MITAP1; mNudel; mNudE-L; 2600006O07Rik

基因 ID: 83431 | 基因类型: protein coding

关于 Ndel1

功能概要

Enables identical protein binding activity and tubulin binding activity. Involved in several processes, including Insulin Receptor signaling pathway; lysosome localization; and regulation of plasma membrane bounded cell projection organization. Acts upstream of or within several processes, including Cytoskeleton organization; generation of neurons; and transport along microtubule. Located in several cellular components, including axon hillock; cytoskeleton; and synaptic vesicle. Part of microtubule associated complex. Is expressed in several structures, including central nervous system; craniocervical region bone; integumental system; metanephros; and sensory organ. Orthologous to human NDEL1 (nudE neurodevelopment protein 1 like 1). [provided by Alliance of Genome Resources, Apr 2022]

Ndel1 基因产物(3)

mRNA Protein Name
NM_001363304.1 NP_001350233.1 nuclear distribution protein nudE-like 1 isoform 2
NM_001363305.1 NP_001350234.1 nuclear distribution protein nudE-like 1 isoform 3
NM_023668.3 NP_076157.2 nuclear distribution protein nudE-like 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables alpha-tubulin binding IDA
IDA: 通过直接分析推断
18331715 MGI
enables beta-tubulin binding IDA
IDA: 通过直接分析推断
18331715 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
17997972 MGI
enables microtubule binding IDA
IDA: 通过直接分析推断
11163259 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11231056 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within activation of GTPase activity IDA
IDA: 通过直接分析推断
18331715 MGI
NOT involved in canonical Wnt signaling pathway IMP
IMP: 通过突变表型推断
20624590 MGI
acts upstream of or within cell migration IMP
IMP: 通过突变表型推断
18331715 MGI
acts upstream of or within central nervous system neuron axonogenesis IMP
IMP: 通过突变表型推断
15208636 MGI
acts upstream of or within centrosome localization IMP
IMP: 通过突变表型推断
18331715 MGI
involved in cerebral cortex radially oriented cell migration IMP
IMP: 通过突变表型推断
20624590 MGI
acts upstream of or within inner cell mass cell proliferation IMP
IMP: 通过突变表型推断
16107726 MGI
involved in insulin receptor signaling pathway IDA
IDA: 通过直接分析推断
28057765 MGI
involved in lysosome localization IMP
IMP: 通过突变表型推断
27777970 MGI
acts upstream of or within microtubule cytoskeleton organization IGI
IGI: 通过遗传相互作用推断
16107726 MGI
acts upstream of or within mitotic centrosome separation IGI
IGI: 通过遗传相互作用推断
17060449 MGI
acts upstream of or within mitotic centrosome separation IMP
IMP: 通过突变表型推断
17060449 MGI
acts upstream of or within neurofilament cytoskeleton organization IMP
IMP: 通过突变表型推断
15208636 MGI
acts upstream of or within neuron migration IGI
IGI: 通过遗传相互作用推断
16107726 MGI
acts upstream of or within neuron projection extension IGI
IGI: 通过遗传相互作用推断
19668197 MGI
involved in positive regulation of ruffle assembly IMP
IMP: 通过突变表型推断
27777970 MGI
acts upstream of or within radial glia-guided pyramidal neuron migration IGI
IGI: 通过遗传相互作用推断
16107726 MGI
involved in regulation of neuron projection development IMP
IMP: 通过突变表型推断
17825401 MGI
acts upstream of or within retrograde axonal transport IDA
IDA: 通过直接分析推断
11163259 MGI
acts upstream of or within vesicle transport along microtubule IGI
IGI: 通过遗传相互作用推断
16107726 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
16203747 MGI
located in axon hillock IDA
IDA: 通过直接分析推断
19668197 MGI
located in cell leading edge IDA
IDA: 通过直接分析推断
18331715 MGI
located in centrosome IDA
IDA: 通过直接分析推断
11163259 MGI
part of microtubule associated complex IDA
IDA: 通过直接分析推断
11163259 MGI
located in microtubule organizing center IGI
IGI: 通过遗传相互作用推断
19668197 MGI
located in neurofilament cytoskeleton IDA
IDA: 通过直接分析推断
15208636 MGI
located in synaptic vesicle IDA
IDA: 通过直接分析推断
18983980 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nuclear distribution protein nudE-like 1

nuclear disribution gene E like

nuclear distribution gene E-like homolog 1

protein Nudel

Ndel1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Ndel1 Q9ERR1 Ywhae Mus musculus P62259
Pull Down
12796778
种属内
Ndel1 Q9ERR1 Ywhae Mus musculus P62259
Anti Bait CoIP
12796778
种属内
Ndel1 Q9ERR1 PAFAH1B1 Homo sapiens P43034
Anti Tag CoIP
26496610
种属内
Ndel1 Q9ERR1 Pafah1b1 Mus musculus P63005
Y2H
11231056
种属内
Ndel1 Q9ERR1 Pafah1b1 Mus musculus P63005
Anti Bait CoIP
12796778
种属内
Ndel1 Q9ERR1 Pafah1b1 Mus musculus P63005
Pull Down
11231056
种属内
Ndel1 Q9ERR1 Ndel1 Mus musculus Q9ERR1
X-Ray Diffraction
17997972
种属内
Ndel1 Q9ERR1 PAFAH1B1 Homo sapiens P43034
Anti Bait CoIP
19927128
种属内
Ndel1 Q9ERR1 Ndel1 Mus musculus Q9ERR1
Solution Sedimentation
17997972
种属内
Ndel1 Q9ERR1 Ndel1 Mus musculus Q9ERR1
CD
17997972
种属内
Ndel1 Q9ERR1 Pafah1b1 Mus musculus P63005
Pull Down
17997972
种属内
Ndel1 Q9ERR1 Pafah1b1 Mus musculus P63005
EPR
17997972
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09107 NDEL1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ndel1 NCBI NCBI:81565
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