2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. L-750667 triHydrochloride

L-750667 triHydrochloride 是一种 D4 多巴胺受体 (D4 dopamine receptor) 的选择性拮抗剂，Ki 值为 0.51 nM。L-750667 的放射性配体形式 [125I]L-750,667 对 D4 受体的 Kd 值为 0.16 nM。L-750667 triHydrochloride 能够逆转多巴胺诱导的对 cAMP 积累的抑制。L-750667 triHydrochloride 可用于研究中枢神经系统中多巴胺 D4 受体的分布和功能，在神经科学和精神病学领域具有潜在的应用价值。

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L-750667 triHydrochloride Chemical Structure

L-750667 triHydrochloride Chemical Structure

CAS No. : 1021868-80-3

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L-750667 triHydrochloride 相关抗体

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生物活性

L-750667 triHydrochloride is a selective antagonist for the D4 dopamine receptor, with a Ki value of 0.51 nM. The radiolabeled form of L-750667, [125I]L-750,667, has a Kd value of 0.16 nM for the D4 receptor. L-750667 triHydrochloride can reverse dopamine-induced inhibition of cAMP accumulation. It can be used to study the distribution and function of D4 dopamine receptors in the central nervous system and has potential applications in the fields of neuroscience and psychiatry[1][2].

IC50 & Target

D4 Receptor

0.51 nM (Ki)

D4 Receptor

0.16 nM (Kd)

分子量

527.66

Formula

C18H22Cl3IN4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

L-750667 triHydrochloride 相关分类

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Keywords:

L-750667 triHydrochloride1021868-80-3Dopamine ReceptorneurosciencepsychiatryInhibitorinhibitorinhibit

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