In situ formation of biomolecular condensates as intracellular drug reservoirs for augmenting chemotherapy

Affiliations

• 1 State Key Laboratory of Advanced Drug Delivery and Release Systems, and Liangzhu Laboratory, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
• 2 School of Materials Science and Engineering, Suzhou University of Science and Technology, Suzhou, China.
• 3 State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
• 4 State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. lpf@sjtu.edu.cn.
• 5 State Key Laboratory of Advanced Drug Delivery and Release Systems, and Liangzhu Laboratory, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China. hongjun@zju.edu.cn.
• 6 Department of Hepatobiliary and Pancreatic Surgery, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. hongjun@zju.edu.cn.
• 7 State Key Laboratory of Advanced Drug Delivery and Release Systems, and Liangzhu Laboratory, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China. guzhen@zju.edu.cn.
• 8 Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China. guzhen@zju.edu.cn.
• 9 Jinhua Institute of Zhejiang University, Jinhua, China. guzhen@zju.edu.cn.
• 10 MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, China. guzhen@zju.edu.cn.
• # Contributed equally.