2. PI3K/Akt/mTOR
  3. PI3K
  4. PI3Kδ/γ-IN-1

PI3Kδ/γ-IN-1 是一种有效、选择性的 PI3Kδ/γ 抑制剂，研究血液系统恶性肿瘤。

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PI3Kδ/γ-IN-1 Chemical Structure

PI3Kδ/γ-IN-1 Chemical Structure

CAS No. : 1980884-01-2

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1 mg ￥1454
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5 mg ￥3200
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10 mg ￥5200
In-stock
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100 mg   询价  

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Customer Review

PI3Kδ/γ-IN-1 相关抗体

Top Publications Citing Use of Products

查看 PI3K 亚型特异性产品:

查看所有亚型
PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PI3Kδ/γ-IN-1 is a potent, selective PI3K-δ/γ inhibitor for research of hematological malignancies.

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Jurkat IC50
1.4 μM
Compound: 12; FMF-02-063-1
Antiproliferative activity against human Jurkat cells after 3 days by CellTiter-Glo assay
Antiproliferative activity against human Jurkat cells after 3 days by CellTiter-Glo assay
[PMID: 27774127]
LOUCY IC50
0.35 μM
Compound: 12; FMF-02-063-1
Antiproliferative activity against human Loucy cells after 3 days by CellTiter-Glo assay
Antiproliferative activity against human Loucy cells after 3 days by CellTiter-Glo assay
[PMID: 27774127]
MOLM-14 IC50
1 μM
Compound: 12; FMF-02-063-1
Antiproliferative activity against human MOLM14 cells after 3 days by CellTiter-Glo assay
Antiproliferative activity against human MOLM14 cells after 3 days by CellTiter-Glo assay
[PMID: 27774127]
MOLT-4 IC50
1.3 μM
Compound: 12; FMF-02-063-1
Antiproliferative activity against human MOLT4 cells after 3 days by CellTiter-Glo assay
Antiproliferative activity against human MOLT4 cells after 3 days by CellTiter-Glo assay
[PMID: 27774127]
MV4-11 IC50
0.62 μM
Compound: 12; FMF-02-063-1
Antiproliferative activity against human MV4-11 cells after 3 days by CellTiter-Glo assay
Antiproliferative activity against human MV4-11 cells after 3 days by CellTiter-Glo assay
[PMID: 27774127]
分子量

508.59

Formula

C25H28N6O4S
CAS 号
性状

固体

颜色

Off-white to gray

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶解性数据
细胞实验： 

DMSO 中的溶解度 : ≥ 2.22 mg/mL (4.37 mM; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

* "≥" means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.9662 mL 9.8311 mL 19.6622 mL
5 mM --- --- ---
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

PI3Kδ/γ-IN-1 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9662 mL 9.8311 mL 19.6622 mL 49.1555 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PI3Kδ/γ-IN-11980884-01-2PI3KPhosphoinositide 3-kinaseInhibitorinhibitorinhibit

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产品名称：
PI3Kδ/γ-IN-1
目录号：
HY-144993
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