1. Apoptosis
  2. Apoptosis
  3. Telomerase-IN-5

Telomerase-IN-5 是一种有效的端粒酶 (telomerase) 抑制剂。Telomerase-IN-5 具有抗增殖活性,诱导细胞凋亡 (apoptosis)。

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Telomerase-IN-5 Chemical Structure

Telomerase-IN-5 Chemical Structure

CAS No. : 2892295-16-6

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Telomerase-IN-5 is a potent telomerase inhibitor. Telomerase-IN-5 has antiproliferative activity and induces apoptosis[1].

体外研究
(In Vitro)

Telomerase-IN-5 (compound 9e; 0.1-100 μg/mL; 72 h) 对两种癌细胞系都有抗肿瘤作用,对 MCF-7 和 A549 细胞的 IC50 值分别为 34.53 和 63.85 μg/mL[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: MCF-7 and A549 cells
Concentration: 0.1, 1, 10, and 100 μg/mL
Incubation Time: 72 h
Result: Inhibited cell growth in a dose-dependent manner.
分子量

420.55

Formula

C22H20N4OS2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Telomerase-IN-5
目录号:
HY-152077
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