Cladribine (Synonyms: 克拉屈滨; 2-Chloro-2′-deoxyadenosine; CldAdo; 2CdA)

目录号: HY-13599 纯度: 99.97%: FAQs
Data Sheet SDS COA 产品使用指南技术支持

Cladribine (2-Chloro-2′-deoxyadenosine) 是一种嘌呤核苷类似物，是具有口服活性的腺苷脱氨酶 (adenosine deaminase) 抑制剂。Cladribine 能作为 DNA 合成 (DNA synthesis) 的抑制剂，可阻断受损 DNA 的修复。Cladribine 可以抑制 DNA 甲基化。Cladribine 具有抗淋巴瘤活性，可用于一些血液恶性肿瘤和多发性硬化的研究。

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Cladribine Chemical Structure

CAS No. : 4291-63-8

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规格	价格	是否有货
10 mM * 1 mL in DMSO	￥500	In-stock
5 mg	￥233	In-stock
10 mg	￥350	In-stock
50 mg	￥1245	In-stock
100 mg	￥2115	In-stock
200 mg		询价
500 mg		询价

or 大包装询价

* Please select Quantity before adding items.

Customer Review

Other Forms of Cladribine:

Cladribine (Standard) 询价

MCE 顾客使用本产品发表的 4 篇科研文献

: Cladribine purchased from MCE. Usage Cited in: Chem Pharm Bull (Tokyo). 2017 Aug 1;65(8):768-775. [Abstract]; Changes in Bcl-2 protein expression in MCF-7 cells after treatment with Cladribine, Dasatinib or Gefitinib alone or in combination for 12 h. Expression of Bcl-2 protein is analyzed by western blotting analysis.

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生物活性
纯度 & 产品资料
参考文献

生物活性

Cladribine (2-Chloro-2′-deoxyadenosine), a purine nucleoside analog, is an orally active adenosine deaminase inhibitor. Cladribine functions as an inhibitor of DNA synthesis to block the repair of the damaged DNA. Cladribine can inhibit DNA methylation. Cladribine has anti-lymphoma activity. Cladribine can be used for the research of several hematologic malignancies and multiple sclerosis^[1]^[2].

IC₅₀ & Target

Adenosine deaminase^[2]

细胞效力
(Cellular Effect)

Cell Line	Type	Value	Description	References
BJ	IC₅₀	> 10 μM Compound: Cladribine	Cytotoxicity against human BJ cells after 3 days by MTT assay Cytotoxicity against human BJ cells after 3 days by MTT assay	[PMID: 21711054]
BT-549	IC₅₀	0.123 μM Compound: Cladribine	Cytotoxicity against human BT549 cells after 3 days by MTT assay Cytotoxicity against human BT549 cells after 3 days by MTT assay	[PMID: 21711054]
BV-173	IC₅₀	0.0008 μM Compound: Cladribine	Cytotoxicity against human BV173 cells after 3 days by MTT assay Cytotoxicity against human BV173 cells after 3 days by MTT assay	[PMID: 21711054]
C6	IC₅₀	9.07 μM Compound: Cladribine	Cytotoxicity against rat C6 cells after 3 days by MTT assay Cytotoxicity against rat C6 cells after 3 days by MTT assay	[PMID: 21711054]
CCRF-CEM	IC₅₀	0.0005 μM Compound: Cladribine	Cytotoxicity against human CCRF-CEM cells after 72 hrs by MTT assay Cytotoxicity against human CCRF-CEM cells after 72 hrs by MTT assay	[PMID: 21840722]
CT26	IC₅₀	0.131 μM Compound: Cladribine	Cytotoxicity against mouse CT26 cells after 3 days by MTT assay Cytotoxicity against mouse CT26 cells after 3 days by MTT assay	[PMID: 21711054]
EL4	IC₅₀	0.848 μM Compound: Cladribine	Cytotoxicity against mouse EL4 cells after 3 days by MTT assay Cytotoxicity against mouse EL4 cells after 3 days by MTT assay	[PMID: 21711054]
HCT-116	IC₅₀	< 0.1 μM Compound: Cladribine	Antiproliferative activity against human HCT116 cells after 72 hrs by SRB assay Antiproliferative activity against human HCT116 cells after 72 hrs by SRB assay	[PMID: 29326016]
HCT-116	IC₅₀	0.3 μM Compound: Cladribine	Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by SRB assay Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by SRB assay	[PMID: 28219046]
HCT-116	IC₅₀	0.3 μM Compound: Cladribine	Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay	[PMID: 25462277]
HCT-116	IC₅₀	9.43 μM Compound: Cladribine	Cytotoxicity against human HCT116 cells after 3 days by MTT assay Cytotoxicity against human HCT116 cells after 3 days by MTT assay	[PMID: 21711054]
HeLa	IC₅₀	> 10 μM Compound: Cladribine	Cytotoxicity against human HeLa cells after 3 days by MTT assay Cytotoxicity against human HeLa cells after 3 days by MTT assay	[PMID: 21711054]
HepG2	IC₅₀	0.04 μM Compound: Cladribine	Antiproliferative activity against human HepG2 cells after 72 hrs by SRB assay Antiproliferative activity against human HepG2 cells after 72 hrs by SRB assay	[PMID: 29326016]
HPAC	IC₅₀	9.32 μM Compound: Cladribine	Cytotoxicity against human HPAC cells after 3 days by MTT assay Cytotoxicity against human HPAC cells after 3 days by MTT assay	[PMID: 21711054]
HT-29	IC₅₀	9.44 μM Compound: Cladribine	Cytotoxicity against human HT-29 cells after 3 days by MTT assay Cytotoxicity against human HT-29 cells after 3 days by MTT assay	[PMID: 21711054]
Huh-7	IC₅₀	0.4 μM Compound: Cladribine	Antiproliferative activity against human HuH7 cells after 72 hrs by SRB assay Antiproliferative activity against human HuH7 cells after 72 hrs by SRB assay	[PMID: 29326016]
Huh-7	IC₅₀	1.8 μM Compound: Cladribine	Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by SRB assay Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by SRB assay	[PMID: 28219046]
Huh-7	IC₅₀	1.8 μM Compound: Cladribine	Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay	[PMID: 25462277]
K562	IC₅₀	0.17 μM Compound: Cladribine	Cytotoxicity against human paclitaxel resistant K562 cells after 3 days by MTT assay Cytotoxicity against human paclitaxel resistant K562 cells after 3 days by MTT assay	[PMID: 21711054]
K562	IC₅₀	10 μM Compound: 1	Antiproliferative activity against human K562 cells assessed as cell growth inhibition after 48 hrs by MTT assay Antiproliferative activity against human K562 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 25960323]
K562	IC₅₀	7.69 μM Compound: Cladribine	Cytotoxicity against human K562 cells after 3 days by MTT assay Cytotoxicity against human K562 cells after 3 days by MTT assay	[PMID: 21711054]
KG-1	IC₅₀	0.2 μM Compound: 1	Antiproliferative activity against human KG1 cells assessed as cell growth inhibition after 48 hrs by MTT assay Antiproliferative activity against human KG1 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 25960323]
L1210	IC₅₀	0.393 μM Compound: Cladribine	Cytotoxicity against mouse L1210 cells after 3 days by MTT assay Cytotoxicity against mouse L1210 cells after 3 days by MTT assay	[PMID: 21711054]
LNCaP	IC₅₀	> 10 μM Compound: Cladribine	Cytotoxicity against human LNCAP cells after 3 days by MTT assay Cytotoxicity against human LNCAP cells after 3 days by MTT assay	[PMID: 21711054]
Mahlavu	IC₅₀	0.1 μM Compound: Cladribine	Antiproliferative activity against human Mahlavu cells after 72 hrs by SRB assay Antiproliferative activity against human Mahlavu cells after 72 hrs by SRB assay	[PMID: 29326016]
MCF7	IC₅₀	2 μM Compound: Cladribine	Antiproliferative activity against human MCF7 cells after 72 hrs by SRB assay Antiproliferative activity against human MCF7 cells after 72 hrs by SRB assay	[PMID: 29326016]
MCF7	IC₅₀	2 μM Compound: Cladribine	Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by SRB assay Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by SRB assay	[PMID: 28219046]
MCF7	IC₅₀	2.35 μM Compound: Cladribine	Cytotoxicity against human MCF7 cells after 3 days by MTT assay Cytotoxicity against human MCF7 cells after 3 days by MTT assay	[PMID: 21711054]
MCF7	IC₅₀	45 μM Compound: 1	Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 25960323]
MDA-MB-231	IC₅₀	> 10 μM Compound: Cladribine	Cytotoxicity against human MDA-MB-231 cells after 3 days by MTT assay Cytotoxicity against human MDA-MB-231 cells after 3 days by MTT assay	[PMID: 21711054]
MES-SA	IC₅₀	0.165 μM Compound: Cladribine	Cytotoxicity against human MES-SA cells after 3 days by MTT assay Cytotoxicity against human MES-SA cells after 3 days by MTT assay	[PMID: 21711054]
MOLT-3	IC₅₀	2.3 μM Compound: 1	Antiproliferative activity against human MOLT3 cells assessed as cell growth inhibition after 48 hrs by MTT assay Antiproliferative activity against human MOLT3 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 25960323]
NCI-H146	IC₅₀	> 10 μM Compound: Cladribine	Cytotoxicity against human NCI-H146 cells after 3 days by MTT assay Cytotoxicity against human NCI-H146 cells after 3 days by MTT assay	[PMID: 21711054]
P388D1	IC₅₀	0.285 μM Compound: Cladribine	Cytotoxicity against mouse P388D1 cells after 3 days by MTT assay Cytotoxicity against mouse P388D1 cells after 3 days by MTT assay	[PMID: 21711054]
PC-3	IC₅₀	8.28 μM Compound: Cladribine	Cytotoxicity against human PC3 cells after 3 days by MTT assay Cytotoxicity against human PC3 cells after 3 days by MTT assay	[PMID: 21711054]
Raji	IC₅₀	0.009 μM Compound: Cladribine	Cytotoxicity against human Raji cells after 72 hrs by MTT assay Cytotoxicity against human Raji cells after 72 hrs by MTT assay	[PMID: 21840722]
RPMI-8226	IC₅₀	6 μM Compound: 1	Antiproliferative activity against human RPMI8226 cells assessed as cell growth inhibition after 48 hrs by MTT assay Antiproliferative activity against human RPMI8226 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 25960323]
SK-HEP1	IC₅₀	4 μM Compound: 1	Antiproliferative activity against human SKHEP1 cells assessed as cell growth inhibition after 48 hrs by MTT assay Antiproliferative activity against human SKHEP1 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 25960323]
SK-MEL-2	IC₅₀	> 10 μM Compound: Cladribine	Cytotoxicity against human SK-MEL-2 cells after 3 days by MTT assay Cytotoxicity against human SK-MEL-2 cells after 3 days by MTT assay	[PMID: 21711054]
SK-N-AS	IC₅₀	> 10 μM Compound: Cladribine	Cytotoxicity against human SK-N-AS cells after 3 days by MTT assay Cytotoxicity against human SK-N-AS cells after 3 days by MTT assay	[PMID: 21711054]
SK-OV-3	IC₅₀	> 10 μM Compound: Cladribine	Cytotoxicity against human SKOV3 cells after 3 days by MTT assay Cytotoxicity against human SKOV3 cells after 3 days by MTT assay	[PMID: 21711054]
Skut1B	IC₅₀	1 μM Compound: 1	Antiproliferative activity against human SK-UT-1B cells assessed as cell growth inhibition after 48 hrs by MTT assay Antiproliferative activity against human SK-UT-1B cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 25960323]
T47D	IC₅₀	0.7 μM Compound: Cladribine	Cytotoxicity against human T47D cells after 72 hrs by SRB assay Cytotoxicity against human T47D cells after 72 hrs by SRB assay	[PMID: 25462277]
U-87MG ATCC	IC₅₀	> 10 μM Compound: Cladribine	Cytotoxicity against human U87MG cells after 3 days by MTT assay Cytotoxicity against human U87MG cells after 3 days by MTT assay	[PMID: 21711054]
ZR-75-1	IC₅₀	> 100 μM Compound: 1	Antiproliferative activity against human ZR-75-1 cells assessed as cell growth inhibition after 48 hrs by MTT assay Antiproliferative activity against human ZR-75-1 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 25960323]

体外研究
(In Vitro)

Cladribine (0.25-4 μM; 24-48 hours) inhibits human DLBCL cells proliferation^[1].
? Cladribine (1-4 μM; 24 hours) induces G1 phase arrest via decreasing the expressions of Cyclin D1 and Cyclin E, and increasing the expressions of p21 and p27 in DLBCL cells^[1].
? Cladribine (1-4 μM; 24 hours) induces apoptosis and activates extrinsic and intrinsic signaling pathways in human DLBCL cells^[1].
? Cladribine (1-4 μM; 24 hours) activates endoplasmic reticulum stress^[1].
? Cladribine inhibits cell proliferation of multiple myeloma (MM) cells in a dose-dependent manner; with IC₅₀s of approximately 2.43 μM, 0.75 μM and 0.18 μM for U266, RPMI8226 and MM1.S cells, respectively^[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay^[1]

Cell Line:	The human DLBCL cell lines (U2932, OCI-LY10, SUDHL2, WSU-DLCL2, DB)
Concentration:	0 μM, 0.25 μM, 0.5 μM, 1 μM, 2 μM, 4 μM
Incubation Time:	24 hours, 48 hours
Result:	Exhibited notable suppression of cell proliferation in five DLBCL cells.

Western Blot Analysis^[1]

Cell Line:	U2932 cells, WSU-DLCL2 cells
Concentration:	0 μM, 1 μM, 2 μM, 4 μM
Incubation Time:	24 hours
Result:	Decreased the expressions of Cyclin D1 and Cyclin E, and increased the expressions of p21 and p27.

Apoptosis Analysis^[1]

Cell Line:	U2932 cells, WSU-DLCL2 cells
Concentration:	0 μM, 1 μM, 2 μM, 4 μM
Incubation Time:	24 hours
Result:	Induced apoptosis and activates exogenous and endogenous apoptotic signaling pathways.

Cell Cycle Analysis^[1]

Cell Line:	U2932 cells, WSU-DLCL2 cells
Concentration:	0 μM, 1 μM, 2 μM, 4 μM
Incubation Time:	24 hours
Result:	Caused G1 phase arrest.

RT-PCR^[1]

Cell Line:	U2932 cells, WSU-DLCL2 cells
Concentration:	0 μM, 1 μM, 2 μM, 4 μM
Incubation Time:	24 hours
Result:	Activated ER stress.

体内研究
(In Vivo)

Cladribine (10 μg/kg; i.p.; 3 times/week; for 2 weeks) may have benefits in the treatment of ischemia/reperfusion injury to the biochemical and histopathologic parameters^[3].
? Cladribine (0.5 mg/kg; i.p.; daily; for 60 days) increases amyloid beta peptide generation and plaque burden in APdE9 mice^[4].
? Cladribine exhibits C_max (rat 4.9 ng/mL) following intra-arterial injection^[5].
? Cladribine exhibits C_max (rat 1.1 ng/mL) following subcutaneous injection^[5].
? Cladribine exhibits elimination half-lives (rat 3.5 h) and plasma clearance (rat 2.8 L/h/kg) following intra-arterial injection^[5].
? Cladribine exhibits elimination half-lives (rat 4.5 h) and plasma clearance (rat 2.3 L/h/kg) following subcutaneous injection^[5].
? Cladribine administration with s.c. injection may produce more favourable pharmacokinetic profiles than i.a. injection following a single dose^[5].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Male Sprague-Dawley rats, ischemic injury model^[3]
Dosage:	10 μg/kg
Administration:	Intraperitoneal injection, 3 times/week, for 2 weeks
Result:	Might increase expression of Sphk1 and consecutively SphK1 suppressed HIF-1α.

Animal Model:	Male Sprague Dawley rats (350-450 g)^[5]
Dosage:	2 mg/kg for s.c., 1 mg/kg for i.a. (Pharmacokinetic Analysis)
Administration:	Subcutaneous injection, intra-arterial
Result:	C_max (4.9 ng/mL i.a.; 1.1 ng/mL s.c.), T_1/2 β (3.5 h i.a.; 4.5 s.c.).

Clinical Trial

分子量

285.69

Formula

C₁₀H₁₂ClN₅O₃

CAS 号

4291-63-8

性状

固体

颜色

White to off-white

中文名称

克拉屈滨

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 1 year; -20°C, 6 months (protect from light)

溶解性数据

细胞实验：

DMSO 中的溶解度 : 200 mg/mL (700.06 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

H₂O 中的溶解度 : 2 mg/mL (7.00 mM; 超声助溶 (<60°C))

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	3.5003 mL	17.5015 mL	35.0030 mL
5 mM	0.7001 mL	3.5003 mL	7.0006 mL
10 mM	0.3500 mL	1.7501 mL	3.5003 mL

查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 1 year; -20°C, 6 months (protect from light)。-80°C储存时，请在1年内使用， -20°C储存时，请在6个月内使用。

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

摩尔计算器
稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

浓度 _(start)

体积 _(start)

浓度 _(final)

体积 _(final)

动物实验：

请根据您的实验动物和给药方式选择适当的溶解方案。

以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：
——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；
以下溶剂前显示的百分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

方案一

请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 5 mg/mL (17.50 mM); 澄清溶液

此方案可获得 ≥ 5 mg/mL（饱和度未知）的澄清溶液。
以 1 mL 工作液为例，取 100 μL 50.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；再向上述体系中加入 50 μL Tween-80，混合均匀；然后再继续加入 450 μL 生理盐水定容至 1 mL。
生理盐水的配制：将 0.9 g 氯化钠，溶解于 ddH₂O 并定容至 100 mL，可以得到澄清透明的生理盐水溶液。

以下溶解方案，请直接配制工作液。建议现用现配，在短期内尽快用完。以下溶剂前显示的百分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶。

方案一

请依序添加每种溶剂： PBS
Solubility: 2 mg/mL (7.00 mM); 澄清溶液; 超声助溶 (<60°C)
方案二

请依序添加每种溶剂： 0.5% CMC-Na/saline water
Solubility: 2 mg/mL (7.00 mM); 澄清溶液; 超声助溶 (<50°C)

动物溶解方案计算器

请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

每只动物的给药体积

μL

动物数量

只

由于实验过程有损耗，建议您多配一只动物的量

请输入您的动物体内配方组成：

DMSO +

Tween-80 +

Saline

如果您的动物是免疫缺陷鼠或者体弱鼠，建议 DMSO 中的在最后工作液体系中的占比尽量不超过 2%。

方案所需 助溶剂 包括：DMSO，，均可在 MCE 网站选购。，Tween 80，均可在 MCE 网站选购。

计算结果

工作液所需浓度 : mg/mL

储备液配制方法 : mg 药物溶于 μL DMSO（母液浓度为 mg/mL）。

*In solvent : -80°C, 1 year; -20°C, 6 months (protect from light)

您所需的储备液浓度超过该产品的实测溶解度，以下方案仅供参考，如有需要，请与 MCE 中国技术支持联系。

动物实验体内工作液的配制方法 : 取 μL DMSO 储备液，加入 μL 。 μL ，混合均匀至澄清，再加 μL Tween 80，混合均匀至澄清，再加 μL 生理盐水。

连续给药周期超过半月以上，请谨慎选择该方案。

请确保第一步储备液溶解至澄清状态，从左到右依次添加助溶剂。您可采用超声加热（超声清洗仪，建议频次 20-40 kHz），涡旋吹打等方式辅助溶解。

纯度 & 产品资料

纯度: 99.97%

选择批次：

Data Sheet (639 KB) SDS (644 KB)

COA (195 KB) LCMS (146 KB)

产品使用指南 (1538 KB)

参考文献

[1]. Linyan Xu, et al. Cladribine Induces ATF4 Mediated Apoptosis and Synergizes with SAHA in Diffuse Large B-Cell Lymphoma Cells. Int J Med Sci. 2020; 17(10): 1375–1384. [Content Brief]

[2]. Jian Ma, et al. Therapeutic potential of cladribine in combination with STAT3 inhibitor against multiple myeloma. BMC Cancer. 2011 Jun 16;11:255. [Content Brief]

[3]. Young Seop Chang, et al. MP28-10 COMBINED EFFECTS OF MELATONIN AND CLADRIBINE ON APOPTOSIS IN ISCHEMIA/REPERFUSION INJURY IN RAT BLADDER. THE JOURNAL OF UROLOGY. April 2016. 195 (4S): e375.

[4]. Crystal D Hayes, et al. Chronic cladribine administration increases amyloid beta peptide generation and plaque burden in mice. PLoS One. 2012;7(10):e45841. [Content Brief]

[5]. Yeung, P. K. F., et al. Pharmacokinetics of Cladribine in a Rat Model Following Subcutaneous and Intra-arterial Injections. Drug Metabol Drug Interact. 2008;23(3-4):291-8. [Content Brief]

Cladribine 相关分类

完整储备液配制表

可选溶剂	浓度溶剂体积质量	1 mg	5 mg	10 mg	25 mg

H₂O / DMSO	1 mM	3.5003 mL	17.5015 mL	35.0030 mL	87.5074 mL
H₂O / DMSO	5 mM	0.7001 mL	3.5003 mL	7.0006 mL	17.5015 mL
DMSO	10 mM	0.3500 mL	1.7501 mL	3.5003 mL	8.7507 mL
	15 mM	0.2334 mL	1.1668 mL	2.3335 mL	5.8338 mL
	20 mM	0.1750 mL	0.8751 mL	1.7501 mL	4.3754 mL
	25 mM	0.1400 mL	0.7001 mL	1.4001 mL	3.5003 mL
	30 mM	0.1167 mL	0.5834 mL	1.1668 mL	2.9169 mL
	40 mM	0.0875 mL	0.4375 mL	0.8751 mL	2.1877 mL
	50 mM	0.0700 mL	0.3500 mL	0.7001 mL	1.7501 mL
	60 mM	0.0583 mL	0.2917 mL	0.5834 mL	1.4585 mL
	80 mM	0.0438 mL	0.2188 mL	0.4375 mL	1.0938 mL
	100 mM	0.0350 mL	0.1750 mL	0.3500 mL	0.8751 mL

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Cladribine (Synonyms: 克拉屈滨; 2-Chloro-2′-deoxyadenosine; CldAdo; 2CdA)

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MCE 顾客使用本产品发表的 4 篇科研文献

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Cladribine (Synonyms: 克拉屈滨; 2-Chloro-2′-deoxyadenosine; CldAdo; 2CdA)

Customer Review

Other Forms of Cladribine:

Cladribine 相关抗体

MCE 顾客使用本产品发表的 4 篇科研文献

Cladribine 相关产品

•相关化合物库:

•同靶点产品:

•同靶点蛋白产品:

生物活性

纯度 & 产品资料

参考文献

Cladribine 相关抗体:

摩尔计算器

稀释计算器

Cladribine 相关分类

完整储备液配制表

Keywords:

您最近查看的产品:

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