2. Cell Cycle/DNA Damage Cytoskeleton
  3. Microtubule/Tubulin
  4. Antitumor agent-71

Antitumor Agent-71 是一种抗肿瘤化合物，可抑制微管蛋白 (tubulin) 聚集。Antitumor Agent-71具有抗增殖活性，对肿瘤细胞系的 IC50 值在3.98-15.70 μM之间。

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Antitumor agent-71 Chemical Structure

Antitumor agent-71 Chemical Structure

CAS No. : 2011756-99-1

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Antitumor agent-71 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antitumor Agent-71 is an antiproliferative activity antitumor agent and against tumor cell lines with IC50 values ranging from 3.98-15.70 μM. Antitumor Agent-71 is an antitumor agent that can inhibit tubulin polymerization.

IC50 & Target

3.98/15.70/10.48/5.38 μM
体外研究
(In Vitro)

Antitumor agent-71 (0.002-20 μM; 48 hours) inhibits the cell line HepG2, MCF-7, MIA PaCa-2, and Bel-7402 growth in a dose-dependent manner[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antitumor agent-71 相关抗体:

Cell Viability Assay

Cell Line: HepG2, MCF-7, MIA PaCa-2, and Bel-7402[1].
Concentration: 0.002-20 μM
Incubation Time: 48h
Result: Showed antitumor activity against HepG2, MIA PaCa-2, MCF-7, and Bel-7402 cell lines with the IC50 values of 3.98/15.70/10.48/5.38 μM.
体内研究
(In Vivo)

Antitumor agent-71 (10-20 mg/kg; intravenous injection; twice a day; 20 days) shows inhibitory effects and inhibits HepG2 cell line in nude mice[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: HepG2 model BALB/c nude mice[1]
Dosage: 10mg/kg, 20mg/kg
Administration: Intravenous injection; twice a day; 20 days
Result: Inhibited tumor growth in a dose-dependent manner.
分子量

509.62

Formula

C26H31N5O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antitumor agent-71 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antitumor agent-712011756-99-1Antitumor agent71Antitumor agent 71Microtubule/TubulinInhibitorinhibitorinhibit

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