2. Apoptosis Autophagy Cell Cycle/DNA Damage Epigenetics
  3. Apoptosis Autophagy HDAC
  4. Entinostat-d4

Entinostat-d4  (Synonyms: MS-275-d4; SNDX-275-d4)

目录号: HY-12163S 纯度: 90.31%
COA 产品使用指南

摩尔计算器

Entinostat-d4 是 Entinostat 的氘代物。 Entinostat 选择性，可口服的 HDAC class I 抑制剂，抑制 HDAC1，HDAC2 和 HDAC3 的 IC50 分别为 243 nM，453 nM 和 248 nM。

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Entinostat-d<sub>4</sub> Chemical Structure

Entinostat-d4 Chemical Structure

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规格 价格 是否有货 数量
500 μg ￥4500
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Customer Review

Other Forms of Entinostat-d4:

Entinostat-d4 相关抗体

Top Publications Citing Use of Products

查看 HDAC 亚型特异性产品:

查看所有亚型
HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Entinostat-d4 is the deuterium labeled Entinostat[1]. Entinostat is an oral and selective class I HDAC inhibitor, with IC50s of 243 nM, 453 nM, and 248 nM for HDAC1, HDAC2, and HDAC3, respectively[2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Entinostat-d4 相关抗体:
分子量

380.43

Formula

C21H16D4N4O3
非标记 CAS
性状

固体

颜色

White to off-white

中文名称

恩替诺特-d4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

Entinostat-d4 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Entinostat-d4MS-275-d4SNDX-275-d4恩替诺特-d4ApoptosisAutophagyHDACHistone deacetylasesInhibitorinhibitorinhibit

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目录号：
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