2. Gene
  3. CYS1 - cystin 1 Gene

CYS1 - cystin 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：胱氨酸 1

种属: Homo sapiens

基因 ID: 192668 | 基因类型: protein coding

关于 CYS1

Cytogenetic location: 2p25.1 Genomic coordinates (GRCh38): 2:10,056,473-10,080,411 (from NCBI)

This gene has 2 transcripts (splice variants) and 45 orthologues. Biased expression in kidney (RPKM 77.2), ovary (RPKM 7.7) and 4 other tissues.

功能概要

预测可实现染色质结合活性和转录辅阻遏物活性。预计在动物器官发育和转录调控的上游或内部发挥作用，以 DNA 为模板。预测位于细胞骨架中；膜筏；和核。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable chromatin binding activity and transcription corepressor activity. Predicted to act upstream of or within animal organ development and regulation of transcription, DNA-templated. Predicted to be located in cytoskeleton; membrane raft; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

CYS1 基因产物(1)

mRNA Protein Name
NM_001037160.3 NP_001032237.1 cystin-1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
22085962 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cystin-1

cilia-associated protein

关联疾病

疾病名称 别名
Polycystic Kidney Disease 4 With Or Without Polycystic Liver Disease

Autosomal Recessive Polycystic Kidney Disease

Arpkd

Polycystic Kidney Disease, Autosomal Recessive

Polycystic Kidney And Hepatic Disease 1

Pkhd1

PKD4

Polycystic Kidney Disease 4 With Or Without Hepatic Disease

Polycystic Kidney Disease, Infantile, Type I

Polycystic Kidney Disease, Infantile Type

Polycystic Kidney, Autosomal Recessive

Pkd3, Formerly

Polycystic Kidney Disease 4, With Or Without Hepatic Disease

Arpkd/Chf

Ar-Pkd

Polycystic Kidney Disease 4, With Or Without Polycystic Liver Disease

Infantile Polycystic Kidney Disease Type I

Pkd3

Kidney, Polycystic, Disease, Type 4, With/Without Hepatic Disease

Polycystic Kidney Disease 3, Autosomal Dominant
Spinocerebellar Ataxia 14

Spinocerebellar Ataxia Type 14

SCA14

Ataxia, Spinocerebellar, Type 14
Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer
Cystic Kidney Disease

Renal Cyst

Simple Renal Cyst

Kidney Cysts

Kidney Diseases, Cystic

Renal Cysts

Kidney Cyst

Cystic Kidney

Congenital Cystic Kidney Disease

Cystic Kidney Diseases

Bosniak 1 Cyst
Autosomal Dominant Polycystic Kidney Disease

Polycystic Kidney Disease, Adult Type

Adpkd

Polycystic Kidney Diseases

Polycystic Kidney, Autosomal Dominant

Congenital Biliary Ectasias

Polycystic Kidney And Hepatic Disease 1

Polycystic Kidney Disease, Autosomal Dominant

Kidney, Polycystic, Disease, Autosomal Dominant

Adult Polycystic Kidney Disease

Polycystic Kidney, Adult Type

Apckd - [Autosomal Polycystic Kidney Disease]
Polycystic Kidney Disease

Polycystic Kidney Diseases

Pkd

Polycystic Renal Disease

Kidney Disease, Polycystic

Polycystic Kidney, Autosomal Dominant
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Approval
生物活性分子 (10)
目录号 产品名 作用方式
纯度 是否罕见病
HY-P0090 Calcitonin (salmon) Agonist 99.95% 否
HY-P0049 Argipressin Agonist 99.82% 否
HY-B1811 Vasopressin 99.83% 是
HY-P1955A Etelcalcetide hydrochloride Activator 99.61% 否
HY-P0004 Lysipressin Activator 98.02% 否
HY-P0083 Ornipressin Agonist 99.63% 否
HY-A0182 Felypressin Agonist 99.62% 否
HY-17584A Linaclotide acetate Agonist 98.61% 否
HY-P1955 Etelcalcetide Activator / 否
HY-P0049A Argipressin diacetate / 否
Clinical Phase
生物活性分子 (5)
目录号 产品名 作用方式
纯度 Phase
HY-A0182A Felypressin acetate Agonist 99.60% Phase 4
HY-P5533 CRT 99.96% Phase 4
HY-W539944 Argipressin acetate / Phase 4
HY-P3448 Certepetide Activator 99.40% Phase 2
HY-106302 Duramycin 99.46% Phase 2
Pre-clinical Phase
生物活性分子 (77)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P0202 Endothelin 1 (swine, human) Activator 99.12% 否
HY-P0256 Apamin Inhibitor 99.71% 否
HY-P0204A Endothelin-3, human, mouse, rabbit, rat TFA 99.96% 否
HY-P0202A Endothelin 1 (swine, human) (TFA) 99.95% 否
HY-P4860 Adropin (34-76) (human, mouse, rat) 99.92% 否
HY-P0189A ω-Conotoxin GVIA TFA Inhibitor 99.20% 否
HY-P1408A Obtustatin triacetate Inhibitor 99.66% 否
HY-P0188A ω-Conotoxin MVIIC TFA Inhibitor 99.95% 否
HY-P0256A Apamin TFA Inhibitor 98.35% 否
HY-P1206 CH 275 Agonist 99.71% 否
HY-P0207A Endothelin-2 (49-69), human TFA Ligand 98.78% 否
HY-P3561A Agouti-related Protein (AGRP) (83-132) Amide (human) (TFA) Inhibitor 96.96% 否
HY-P10388 TAX2 peptide 98.70% 否
HY-P3215 Oxytocin parallel dimer Activator 98.45% 否
HY-P5141A µ-Conotoxin KIIIA TFA Inhibitor 99.20% 否
HY-P4605A (Ile8)-Oxytocin acetate 99.65% 否
HY-102029 Sarafotoxin S6c Agonist 98.19% 否
HY-17571F Biotin-Oxytocin 99.25% 否
HY-P10235 Cyclic AC253 Antagonist 99.87% 否
HY-P10557 DAG peptide 99.61% 否
HY-P1408 Obtustatin Inhibitor 99.69% 否
HY-P2526 LyP-1 98.46% 否
HY-P0204 Endothelin-3, human, mouse, rabbit, rat / 否
HY-P0207 Endothelin-2 (49-69), human Ligand / 否
HY-P10383 SPSB2-iNOS inhibitory cyclic peptide-1 99.81% 否
HY-P1463 Calcitonin, eel / 否
HY-P1463A Calcitonin, eel TFA 99.91% 否
HY-P1574 [Arg8]-Vasotocin / 否
HY-P1574A [Arg8]-Vasotocin TFA 98.41% 否
HY-P1789A CTTHWGFTLC, CYCLIC TFA Inhibitor 98.91% 否
HY-P2538 Big Endothelin-1 (1-38), human Agonist 81.54% 否
HY-P3215A Oxytocin parallel dimer TFA Activator 98.10% 否
HY-P4678 (Phe2,Orn8)-Oxytocin Agonist 98.22% 否
HY-P0090S Calcitonin-13C6,15N4 (salmon) TFA Agonist / 否
HY-P0090A Calcitonin (salmon) (acetate) Agonist / 否
HY-P0188 ω-Conotoxin MVIIC Inhibitor / 否
HY-P0189 ω-Conotoxin GVIA Inhibitor / 否
HY-P10237 Calcitonin (chicken) Modulator / 否
HY-P10328 Vasoactive intestinal contractor Inhibitor / 否
HY-P10383A SPSB2-iNOS inhibitory cyclic peptide-1 TFA / 否
HY-P10693 CZEN-002 Inhibitor / 否
HY-P10698 VH-N412 / 否
HY-P10826 PD-1/PD-L1 inhibitory peptide C8 Inhibitor / 否
HY-P10835 LAG-3 cyclic peptide inhibitor C25 Inhibitor / 否
HY-P10837 LAG-3 cyclic peptide inhibitor 12 Inhibitor / 否
HY-P10924 Roseltide rT1 Inhibitor / 否
HY-P1372 PKC ζ pseudosubstrate Inhibitor / 否
HY-P1789 CTTHWGFTLC, CYCLIC Inhibitor / 否
HY-P2005 Malformin C / 否
HY-P2496 Endothelin 1 (swine, human), Alexa Fluor 488-labeled Activator / 否
HY-P2539 Big Endothelin-1 (1-39), porcine Agonist / 否
HY-P3433 Sarafotoxin S6b Agonist / 否
HY-P3561 Agouti-related Protein (AGRP) (83-132) Amide (human) Antagonist / 否
HY-P3563 [Lys4] Sarafotoxin S6c Agonist / 否
HY-P3565 Sarafotoxin S6d / 否
HY-P3571 [Ala2] Endothelin-3, human / 否
HY-P3682 w-Conotoxin SVIB Antagonist / 否
HY-P4205 Aminopeptidase N Ligand (CD13) NGR peptide Inhibitor / 否
HY-P4320 Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys (Disulfide bridge:cys1-cys10) Antagonist / 否
HY-P4605 (Ile8)-Oxytocin / 否
HY-P4678A (Phe2,Orn8)-Oxytocin acetate Agonist / 否
HY-P4990 Pro8-Oxytocin Activator / 否
HY-P4990A Pro8-Oxytocin TFA Activator / 否
HY-P4994 Val9-Oxytocin Antagonist / 否
HY-P5010 (D-Arg8)-Inotocin Antagonist / 否
HY-P5017 (Val3,Pro8)-Oxytocin Agonist / 否
HY-P5130 Big endothelin-1 (rat 1-39) Ligand / 否
HY-P5140 ω-Tbo-IT1 Inhibitor / 否
HY-P5143 ω-Conotoxin SO3 Inhibitor / 否
HY-P5568 Siamycin III Inhibitor / 否
HY-P5738 Palicourein Inhibitor / 否
HY-P5820 ω-Conotoxin Bu8 Inhibitor / 否
HY-P5902 ω-conotoxin MoVIA Inhibitor / 否
HY-P5907 Helianorphin-19 Activator / 否
HY-RS03493 CYS1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-P0083A Ornipressin acetate Agonist / 否
HY-P3226 JB-1 Antagonist / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus CYS1 RGD RGD:1596023
Mus musculus CYS1 MGD MGI:2177632
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