Pik3c3 - phosphatidylinositol 3-kinase catalytic subunit type 3 Gene

中文名称：磷脂酰肌醇 3-激酶催化亚基 3 型

种属: Mus musculus

同用名: Vps34; 5330434F23Rik

关于 Pik3c3

功能概要

该基因编码的蛋白可启动蛋白激酶活性。参与细胞对葡萄糖饥饿和巨自噬的反应。作用于多个过程的上游或内部，包括细胞对饥饿的反应；磷脂酰肌醇-3-磷酸生物合成过程；和蛋白质定位到吞噬细胞组装位点。位于吞噬泡内。磷脂酰肌醇 3-激酶复合物的一部分，III 类。在 Meckel 的软骨中表达；心血管系统;肢;和骨架。与人 PIK3C3（磷脂酰肌醇 3-激酶催化亚基 3 型）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables protein kinase activity. Involved in cellular response to glucose starvation and macroautophagy. Acts upstream of or within several processes, including cellular response to starvation; phosphatidylinositol-3-phosphate biosynthetic process; and protein localization to phagophore assembly site. Located in phagocytic vesicle. Part of phosphatidylinositol 3-kinase complex, class III. Is expressed in Meckel's cartilage; cardiovascular system; limb; and skeleton. Orthologous to human PIK3C3 (phosphatidylinositol 3-kinase catalytic subunit type 3). [provided by Alliance of Genome Resources, Apr 2022]