2. Gene
  3. RRP1B - ribosomal RNA processing 1B Gene

RRP1B - ribosomal RNA processing 1B Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：核糖体 RNA 加工 1B

种属: Homo sapiens

同用名: Nnp1; RRP1; NNP1L; KIAA0179; PPP1R136

基因 ID: 23076 | 基因类型: protein coding

关于 RRP1B

Cytogenetic location: 21q22.3 Genomic coordinates (GRCh38): 21:43,659,560-43,696,079 (from NCBI)

This gene has 2 transcripts (splice variants), 197 orthologues and 1 paralogue. Ubiquitous expression in lymph node (RPKM 10.6), testis (RPKM 10.3) and 25 other tissues.

功能概要

启用转录共激活因子活性。参与多个过程，包括细胞对病毒的反应；宿主对病毒转录的正调控；和 RNA 聚合酶 II 对转录的正调控。位于染色体；粒状成分；和核质。 [由基因组资源联盟提供，2022 年 4 月]

Enables transcription coactivator activity. Involved in several processes, including cellular response to virus; positive regulation by host of viral transcription; and positive regulation of transcription by RNA polymerase II. Located in chromosome; granular component; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RRP1B 基因产物(1)

mRNA Protein Name
NM_015056.3 NP_055871.1 ribosomal RNA processing protein 1 homolog B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19389623 GOA
enables transcription coactivator activity IMP
IMP: 通过突变表型推断
20040599 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to virus IDA
IDA: 通过直接分析推断
26311876 GOA
involved in positive regulation by host of viral transcription IMP
IMP: 通过突变表型推断
26311876 GOA
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
20040599 GOA
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
20040599 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in granular component IDA
IDA: 通过直接分析推断
20926688 GOA
located in nucleolus IDA
IDA: 通过直接分析推断
20040599 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RRP1B 蛋白结构

Nop52

Nop52: Nucleolar protein,Nop52 (9 - 219)

  • 0
  • 200
  • 400
  • 600
  • 758 a.a.
蛋白主名 其他名称

ribosomal RNA processing protein 1 homolog B

RRP1-like protein B

RRP1B 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra RRP1B Q14684 RRP1 Homo sapiens P56182
Anti Tag CoIP
20926688
Intra RRP1B Q14684 PPP1CB Homo sapiens P62140
Anti Tag CoIP
20926688
Intra RRP1B Q14684 RPL27 Homo sapiens P61353
Anti Tag CoIP
20926688
Intra RRP1B Q14684 PPP1CC Homo sapiens P36873
Density Sedimentation
20926688
Intra RRP1B Q14684 PPP1CC Homo sapiens P36873
Anti Tag CoIP
20926688
Intra RRP1B Q14684 PPP1CA Homo sapiens P62136
Anti Tag CoIP
20926688
Intra RRP1B Q14684 RPL5 Homo sapiens P46777
Anti Tag CoIP
20926688
Intra RRP1B Q14684 FBL Homo sapiens P22087
Anti Tag CoIP
20926688
Intra RRP1B Q14684 SRSF1 Homo sapiens Q07955
Anti Bait CoIP
23604122
Intra RRP1B Q14684 SRSF1 Homo sapiens Q07955
Confocal
23604122
Intra RRP1B Q14684 SRSF1 Homo sapiens Q07955
Anti Tag CoIP
23604122
Intra RRP1B Q14684 SRSF1 Homo sapiens Q07955
Anti Tag CoIP
20926688
Intra RRP1B Q14684 E2F1 Homo sapiens Q01094
BiFC
20040599
Intra RRP1B Q14684 E2F1 Homo sapiens Q01094
Anti Tag CoIP
20040599
Intra RRP1B Q14684 E2F1 Homo sapiens Q01094
CH-IP
20040599
Intra RRP1B Q14684 E2F1 Homo sapiens Q01094
Pull Down
20040599
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Microinvasive Gastric Cancer

Early Gastric Cancer

Surface Gastric Cancer
Laryngeal Squamous Cell Carcinoma

Epidermoid Carcinoma Of The Larynx

Squamous Cell Carcinoma Of Larynx

Squamous Cell Carcinoma Of The Larynx

Squamous Cell Carcinoma Of Head And Neck
Influenza

Flu

Influenza With Non-Respiratory Manifestation

Influenza With Other Manifestations

Influenza, Human

Influenza, Susceptibility To

Seasonal Influenza, Virus Identified
Osteogenesis Imperfecta, Type Xii

Osteogenesis Imperfecta Type 12

OI12

Osteogenesis Imperfecta Type Xii

Oi, Type Xii

Osteogenesis Imperfecta 12

Oi Type Xii

Oi-Xii

Osteogenesis Imperfecta Sillence Type Iii
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12291 RRP1B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus RRP1B MGD MGI:1919712
Canis familiaris RRP1B VGNC VGNC:45766
Felis catus RRP1B VGNC VGNC:64781
Macaca mulatta RRP1B VGNC VGNC:77089
Rattus norvegicus RRP1B RGD RGD:1305633
Bos taurus RRP1B VGNC VGNC:34170
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