2. Gene
  3. Tf - transferrin Gene

Tf - transferrin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Tfn; Trf

基因 ID: 24825 | 基因类型: protein coding

关于 Tf

功能概要

Enables ferric iron binding activity. Involved in several processes, including cellular response to cAMP; cellular response to follicle-stimulating hormone stimulus; and regulation of nervous system development. Located in basement membrane; cell tip; and extracellular space. Used to study hepatitis. Biomarker of anemia and obesity. Human ortholog(s) of this gene implicated in anemia; atransferrinemia; glucose metabolism disease (multiple); iron deficiency anemia; and restless legs syndrome. Orthologous to human TF (transferrin). [provided by Alliance of Genome Resources, Apr 2022]

Tf 基因产物(1)

mRNA Protein Name
NM_001013110.1 NP_001013128.1 serotransferrin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ferric iron binding IDA
IDA: 通过直接分析推断
17373738 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acute-phase response IEP
IEP: 通过表达模式推断
17417667 RGD
involved in cellular response to cAMP IEP
IEP: 通过表达模式推断
15831523 RGD
involved in cellular response to follicle-stimulating hormone stimulus IEP
IEP: 通过表达模式推断
15831523 RGD
involved in iron ion transport IDA
IDA: 通过直接分析推断
17373738 RGD
involved in positive regulation of myelination IDA
IDA: 通过直接分析推断
16480980 RGD
involved in positive regulation of oligodendrocyte progenitor proliferation IDA
IDA: 通过直接分析推断
23368675 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
16479386 RGD
involved in response to lead ion IEP
IEP: 通过表达模式推断
23007736 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
16519141 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basement membrane IDA
IDA: 通过直接分析推断
1723977 RGD
located in cell tip IDA
IDA: 通过直接分析推断
17373738 RGD
located in dendrite IDA
IDA: 通过直接分析推断
26109571 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
17350134 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

serotransferrin

beta-1 metal-binding globulin

liver regeneration-related protein LRRG03

siderophilin

重组 Tf 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73454 Transferrin Protein, Rat (HEK293, His) P12346 (V20-S698) ≥95%

相关产品

Approval
生物活性分子 (3)
目录号 产品名 作用方式
纯度 是否罕见病
HY-18763 Indobufen Inhibitor 99.98% 否
HY-13682C Mifamurtide TFA ≥98.0% 否
HY-P0062A Ziconotide TFA Antagonist / 否
Clinical Phase
生物活性分子 (7)
目录号 产品名 作用方式
纯度 Phase
HY-P5533 CRT 99.96% Phase 4
HY-P0171 Motixafortide Antagonist 99.88% Phase 3
HY-152963 Tisotumab vedotin 99.69% Phase 3
HY-19284 FR-146687 Inhibitor / Phase 2
HY-N1992 Theaflavin 3,3'-digallate Inhibitor 99.73% Phase 1
HY-P0173B Chlorotoxin TFA Inhibitor 98.46% Phase 1
HY-153480 ARC19499 Inhibitor 93.65% Phase 1
抗体抑制剂 (2)
目录号 产品名 作用方式
纯度 Phase
HY-P99271 Tisotumab ≥95.0% Phase 3
HY-P990090 Rademikibart Inhibitor 98.69% Phase 3
Pre-clinical Phase
生物活性分子 (23)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-100388 SHP099 Inhibitor 99.80% 否
HY-134094 Fluridone 99.79% 否
HY-P2196A ELA-32(human) TFA Agonist 99.27% 否
HY-P0188A ω-Conotoxin MVIIC TFA Inhibitor 99.95% 否
HY-153480A ARC19499 sodium Inhibitor 93.65% 否
HY-P5875A P4pal10 TFA Antagonist 98.25% 否
HY-148880 VHLL-BCN / 否
HY-116170 SN34037 / 否
HY-155951 JAK3-IN-14 Inhibitor 99.32% 否
HY-156158 IDH2R140Q-IN-2 Inhibitor / 否
HY-162490 TF-S14 Inhibitor / 否
HY-169335 HIV-1 inhibitor-77 Inhibitor / 否
HY-170723 JAK-IN-39 Inhibitor / 否
HY-18763A Indobufen sodium Inhibitor / 否
HY-18763S Indobufen-d5 Inhibitor / 否
HY-N10308 TF-DG-cThea / 否
HY-N10310 TF-3-G-cThea / 否
HY-P1636A Hirudin (54-65) TFA Inhibitor / 否
HY-P5152 Scorpion toxin Tf2 Activator / 否
HY-P5875 P4pal10 Antagonist / 否
HY-RS14406 TF Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-13496 JNJ-28312141 Inhibitor / 否
HY-N10309 TF-3ʹ-G-cThea / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tf NCBI NCBI:7018
Canis familiaris Tf NCBI
Macaca fascicularis Tf NCBI NCBI:101866521
Mus musculus Tf NCBI
Susscrofa domestica Tf NCBI
Leporidae Tf NCBI
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