ROS1 - ROS proto-oncogene 1 , receptor tyrosine kinase Gene

中文名称：ROS 原癌基因1 受体酪氨酸激酶

种属: Rattus norvegicus

同用名: ROS1C

关于 ROS1

功能概要

预测该基因编码的蛋白编码的蛋白可启动蛋白磷酸酶结合活性和跨膜受体蛋白酪氨酸激酶活性。预计参与多个过程，包括柱状/立方形上皮细胞发育；激酶活性的正调节；和细胞内信号转导的调节。预计在几个过程的上游或内部起作用，包括基因表达的负调控；肽基酪氨酸自磷酸化；磷酸盐运输的调节。预测位于细胞表面和细胞质的核周区。预计是受体复合体的一部分。预计是质膜的组成部分。与人类 ROS1（ROS 原癌基因 1，受体酪氨酸激酶）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable protein Phosphatase binding activity and transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in several processes, including columnar/cuboidal epithelial cell development; positive regulation of kinase activity; and regulation of intracellular signal transduction. Predicted to act upstream of or within several processes, including negative regulation of gene expression; peptidyl-tyrosine autophosphorylation; and regulation of phosphate transport. Predicted to be located in cell surface and perinuclear region of cytoplasm. Predicted to be part of receptor complex. Predicted to be integral component of plasma membrane. Orthologous to human ROS1 (ROS proto-oncogene 1, receptor tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]