2. Gene
  3. Fadd - Fas associated via death domain Gene

Fadd - Fas associated via death domain Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Mort1

基因 ID: 266610 | 基因类型: protein coding

关于 Fadd

功能概要

Enables protease binding activity; receptor serine/threonine kinase binding activity; and tumor necrosis factor receptor superfamily binding activity. Involved in kidney development; regulation of necroptotic process; and response to alkaloid. Located in several cellular components, including cell body; membrane raft; and neuron projection. Part of CD95 death-inducing signaling complex. Used to study morphine dependence and prostatic hypertrophy. Biomarker of several diseases, including abdominal obesity-metabolic syndrome 1; brain glioma; mental depression; middle cerebral artery infarction; and obesity. Human ortholog(s) of this gene implicated in leukemia. Orthologous to human FADD (Fas associated via death domain). [provided by Alliance of Genome Resources, Apr 2022]

Fadd 基因产物(1)

mRNA Protein Name
NM_152937.2 NP_690920.1 FAS-associated death domain protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables death receptor binding IPI
IPI: 通过物理相互作用推断
17518537 RGD
enables protease binding IPI
IPI: 通过物理相互作用推断
17518537 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
19001025 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
17518537 RGD
enables receptor serine/threonine kinase binding IPI
IPI: 通过物理相互作用推断
26038570 RGD
enables tumor necrosis factor receptor binding IPI
IPI: 通过物理相互作用推断
20649583 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in behavioral response to cocaine IEP
IEP: 通过表达模式推断
18580876 RGD
involved in kidney development IEP
IEP: 通过表达模式推断
27561622 RGD
involved in regulation of necroptotic process IMP
IMP: 通过突变表型推断
26038570 RGD
involved in response to cocaine IEP
IEP: 通过表达模式推断
21925237 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of CD95 death-inducing signaling complex IDA
IDA: 通过直接分析推断
16493077 RGD
located in cell body IDA
IDA: 通过直接分析推断
18096138 RGD
part of death-inducing signaling complex IDA
IDA: 通过直接分析推断
17518537 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
15590916 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

FAS-associated death domain protein

Fas (TNFRSF6)-associated via death domain

protein FADD

Fadd 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Fadd Q8R2E7 Casp8 Rattus norvegicus Q9JHX4
Anti Bait CoIP
19001025
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-14622 Necrostatin 2 Inhibitor 99.92% 否
HY-109582 ADT-OH Inducer 99.06% 否
HY-132203 Necrostatin-34 Inhibitor 98.90% 否
HY-148454 Necroptosis-IN-3 Inhibitor 99.77% 否
HY-RS04665 FADD Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-168770 Cl-Necrostatin-1 Inhibitor / 否
HY-119369 FadD32 Inhibitor-1 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fadd NCBI NCBI:8772
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