2. Gene
  3. Cd47 - Cd47 molecule Gene

Cd47 - Cd47 molecule Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Itgp

基因 ID: 29364 | 基因类型: protein coding

关于 Cd47

功能概要

Enables protein binding activity involved in heterotypic cell-cell adhesion. Involved in several processes, including cellular response to cytokine stimulus; positive regulation of monocyte extravasation; and regulation of phagocytosis. Located in cell surface. Orthologous to human CD47 (CD47 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd47 基因产物(1)

mRNA Protein Name
NM_019195.2 NP_062068.1 leukocyte surface antigen CD47 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding involved in heterotypic cell-cell adhesion IPI
IPI: 通过物理相互作用推断
16055727 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell migration IDA
IDA: 通过直接分析推断
12023387 RGD
involved in cellular response to interleukin-1 IMP
IMP: 通过突变表型推断
12023387 RGD
involved in cellular response to type II interferon IMP
IMP: 通过突变表型推断
12023387 RGD
involved in negative regulation of phagocytosis IMP
IMP: 通过突变表型推断
21401967 RGD
involved in positive regulation of monocyte extravasation IMP
IMP: 通过突变表型推断
12023387 RGD
involved in positive regulation of phagocytosis IMP
IMP: 通过突变表型推断
23238794 RGD
involved in positive regulation of stress fiber assembly IMP
IMP: 通过突变表型推断
12023387 RGD
involved in regulation of Fc receptor mediated stimulatory signaling pathway IMP
IMP: 通过突变表型推断
21401967 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
12023387 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

leukocyte surface antigen CD47

CD47 antigen (Rh-related antigen, integrin-associated signal transducer)

IAP

integrin-associated protein

重组 Cd47 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75401 CD47 Protein, Rat (HEK293, His) P97829-1 (Q19-K140) ≥95%
HY-P75402 CD47 Protein, Rat (HEK293, Fc) P97829-1 (Q19-K140) ≥95%

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-16438 RRx-001 Inhibitor 99.16% Phase 3
抗体抑制剂 (7)
目录号 产品名 作用方式
纯度 Phase
HY-P99029 Magrolimab Inhibitor 99.92% Phase 3
HY-P99950 Evorpacept Inhibitor / Phase 3
HY-P99777 Ontorpacept Inhibitor 99.57% Phase 2
HY-P99026 Lemzoparlimab Inhibitor / Phase 2
HY-P99172 CC-90002 Inhibitor 97.97% Phase 1
HY-P990033 Anzurstobart Inhibitor 98.53% Phase 1
HY-P99533 Urabrelimab Inhibitor 98.49% Phase 1
Pre-clinical Phase
生物活性分子 (13)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-143224B NCGC00138783 TFA Inhibitor 99.71% 否
HY-136780 SEN177 97.10% 否
HY-P0144 Thrombospondin-1 (1016-1023) (human, bovine, mouse) Inhibitor 99.08% 否
HY-115983 DMUP Inhibitor ≥98.0% 否
HY-P10388 TAX2 peptide Inhibitor / 否
HY-143224 NCGC00138783 Inhibitor / 否
HY-151132 Glutaminyl cyclases-IN-1 Inhibitor 98.21% 否
HY-P10420 RS17 Inhibitor 99.82% 否
HY-143224A NCGC00138783 free base Inhibitor / 否
HY-P10813 ZLIRTLHEWY Inhibitor / 否
HY-143225 NCGC00538431 Inhibitor / 否
HY-P3968 Thrombospondin-1 (1016-1021) (human, bovine, mouse) / 否
HY-RS02250 CD47 Human Pre-designed siRNA Set A Inhibitor / 否
抗体抑制剂 (17)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P99175 KWAR 23 Inhibitor 99.80% 否
HY-P99706 Ligufalimab Inhibitor 98.81% 否
HY-P990132 Anti-Mouse/Rat/Human CD47/IAP Antibody (MIAP410) Inhibitor 95.00% 否
HY-P990858 Anti-CD47 Antibody (B6.H12) Inhibitor 95.00% 否
HY-P990131 Anti-Mouse CD47/IAP Antibody (MIAP301) Inhibitor 95.00% 否
HY-P990555 BI-765063 Inhibitor / 否
HY-P991027 Spevatamig / 否
HY-P991004 Itanistomig / 否
HY-P990707 Maplirpacept / 否
HY-P991016 Peluntamig / 否
HY-P990899 Amostomig / 否
HY-P990954 Amulirafusp alfa / 否
HY-P991023 Safimestomig / 否
HY-P990723 Timdarpacept Inhibitor / 否
HY-P990694 Zeripatamig Inhibitor / 否
HY-P991057 STI-6643 Inhibitor / 否
HY-P991062 Gentulizumab Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cd47 NCBI NCBI:961
Macaca fascicularis Cd47 NCBI NCBI:102139846
Mus musculus Cd47 NCBI NCBI:16423
Macaca mulatta Cd47 NCBI NCBI:704980
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