2. Gene
  3. Csk - C-terminal Src kinase Gene

Csk - C-terminal Src kinase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 315707 | 基因类型: protein coding

关于 Csk

功能概要

Enables proline-rich region binding activity; protein Phosphatase binding activity; and protein tyrosine kinase activity. Involved in several processes, including central nervous system development; negative regulation of bone resorption; and regulation of MAPK cascade. Located in cytoplasm and membrane raft. Biomarker of hepatocellular carcinoma. Orthologous to human CSK (C-terminal Src kinase). [provided by Alliance of Genome Resources, Apr 2022]

Csk 基因产物(1)

mRNA Protein Name
NM_001030039.1 NP_001025210.1 tyrosine-protein kinase CSK
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables proline-rich region binding IPI
IPI: 通过物理相互作用推断
8890164 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
21873224 RGD
enables protein phosphatase binding IPI
IPI: 通过物理相互作用推断
8890164 RGD
enables protein tyrosine kinase activity IDA
IDA: 通过直接分析推断
7683130 RGD
enables protein tyrosine kinase binding IPI
IPI: 通过物理相互作用推断
12700184 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in adherens junction organization IEP
IEP: 通过表达模式推断
15389520 RGD
involved in cellular response to peptide hormone stimulus IDA
IDA: 通过直接分析推断
17071733 RGD
involved in negative regulation of ERK1 and ERK2 cascade IDA
IDA: 通过直接分析推断
9325302 RGD
involved in negative regulation of bone resorption IDA
IDA: 通过直接分析推断
10411542 RGD
involved in negative regulation of cell population proliferation IDA
IDA: 通过直接分析推断
10411542 RGD
involved in negative regulation of interleukin-6 production IDA
IDA: 通过直接分析推断
10411542 RGD
involved in negative regulation of kinase activity IDA
IDA: 通过直接分析推断
10411542 RGD
involved in negative regulation of low-density lipoprotein particle clearance IDA
IDA: 通过直接分析推断
10884975 RGD
involved in negative regulation of phagocytosis IDA
IDA: 通过直接分析推断
10884975 RGD
involved in oligodendrocyte differentiation IEP
IEP: 通过表达模式推断
15504915 RGD
involved in positive regulation of MAP kinase activity IDA
IDA: 通过直接分析推断
10884975 RGD
involved in protein autophosphorylation IDA
IDA: 通过直接分析推断
7683130 RGD
involved in protein phosphorylation IDA
IDA: 通过直接分析推断
7683130 RGD
involved in regulation of Fc receptor mediated stimulatory signaling pathway IDA
IDA: 通过直接分析推断
9325302 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
21873224 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tyrosine-protein kinase CSK

C-SRC kinase

CSK, non-receptor tyrosine kinase

c-src tyrosine kinase

protein-tyrosine kinase (CSK)

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-15196 TAK-285 Inhibitor 99.70% Phase 1
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P9928A Alirocumab (anti-PCSK9) Inhibitor 98.24% Phase 4
Pre-clinical Phase
生物活性分子 (19)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P1180A Pam3CSK4 TFA Agonist 99.66% 否
HY-108471 CU-CPT22 Inhibitor ≥99.0% 否
HY-112146 MMG-11 Antagonist 99.24% 否
HY-130254 CSK-IN-1 Inhibitor 98.61% 否
HY-122113 PD173952 99.44% 否
HY-P1181A Pam2CSK4 TFA Agonist 99.28% 否
HY-148063 DB0614 98.80% 否
HY-137345 DB-3-291 Inhibitor 98.03% 否
HY-148061 DB1113 99.28% 否
HY-130504 Propargyl-PEG1-acid ≥97.0% 否
HY-112146A MMG-11 quarterhydrate Antagonist 99.09% 否
HY-P1180 Pam3CSK4 Agonist / 否
HY-118105 RK-20448 Inhibitor 99.38% 否
HY-P10527 CSK substrate / 否
HY-P1180B Pam3CSK4 trihydrochloride / 否
HY-P1181 Pam2CSK4 Agonist / 否
HY-P1405 Pam3CSK4-Biotin Agonist / 否
HY-RS03238 CSK Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-W114420 3-Methyl-L-tyrosine / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Csk NCBI NCBI:1445
Macaca fascicularis Csk NCBI NCBI:102131034
Mus musculus Csk NCBI NCBI:12988
Macaca mulatta Csk NCBI NCBI:702868
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