Cgas - cyclic GMP-AMP synthase Gene

中文名称：环状 GMP-AMP 合酶

种属: Rattus norvegicus

同用名: Mb21d1

关于 Cgas

功能概要

预计该基因编码的蛋白具有多种功能，包括 2',3'-环状 GMP-AMP 合酶活性；染色质结合活性；和磷脂酰肌醇-4,5-二磷酸结合活性。预计参与多个过程，包括细胞内信号转导的正调控；调节细胞对压力的反应；和防御反应的调节。预计在几个过程的上游或内部起作用，包括确定成人寿命；调节 T 细胞活化；和基因表达的调控。预计位于几种细胞成分中，包括细胞质；核;和双链断裂位点。与人 CGAS（环状 GMP-AMP 合酶）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable several functions, including 2',3'-cyclic GMP-AMP synthase activity; chromatin binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in several processes, including positive regulation of intracellular signal transduction; regulation of cellular response to stress; and regulation of defense response. Predicted to act upstream of or within several processes, including determination of adult lifespan; regulation of T cell activation; and regulation of gene expression. Predicted to be located in several cellular components, including cytosol; nucleus; and site of double-strand break. Orthologous to human CGAS (Cyclic GMP-AMP Synthase). [provided by Alliance of Genome Resources, Apr 2022]