1. Gene
  2. ACCS - 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) Gene

ACCS - 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) Gene

中文名称:1-氨基环丙烷-1-羧酸合酶同系物 (无活性)

种属: Homo sapiens

同用名: ACS; PHACS

基因 ID: 84680 | 基因类型: protein coding

关于 ACCS

Cytogenetic location: 11p11.2 Genomic coordinates (GRCh38): 11:44,066,270-44,084,237 (from NCBI)

This gene has 13 transcripts (splice variants), 149 orthologues and 7 paralogues. Ubiquitous expression in spleen (RPKM 11.2), gall bladder (RPKM 7.3) and 25 other tissues.

功能概要

实现相同的蛋白质结合活性。预计参与生物合成过程。 [由基因组资源联盟提供,2022 年 4 月]

Enables identical protein binding activity. Predicted to be involved in biosynthetic process. [provided by Alliance of Genome Resources, Apr 2022]

ACCS 基因产物(2)

mRNA Protein Name
NM_001127219.2 NP_001120691.1 1-aminocyclopropane-1-carboxylate synthase-like protein 1
NM_032592.4 NP_115981.1 1-aminocyclopropane-1-carboxylate synthase-like protein 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
NOT enables 1-aminocyclopropane-1-carboxylate synthase activity IDA
IDA: 通过直接分析推断
11470512 GOA
enables identical protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

ACCS 蛋白结构

Aminotran_1_2

Aminotran_1_2: Aminotransferase class I and II (98 - 460)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 501 a.a.
蛋白主名 其他名称

1-aminocyclopropane-1-carboxylate synthase-like protein 1

ACC synthase-like protein 1

ACCS 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra ACCS Q96QU6 UQCRB Homo sapiens P14927
Y2H Prey Pooling
25416956
Intra ACCS Q96QU6 ACCS Homo sapiens Q96QU6
Y2H Array
31515488
Intra ACCS Q96QU6 ACCS Homo sapiens Q96QU6
Y2H Prey Pooling
32296183
Intra ACCS Q96QU6 ACCS Homo sapiens Q96QU6-1
Y2H Array
31515488
Intra ACCS Q96QU6 ACCS Homo sapiens Q96QU6
Validated Y2H
32296183
Intra ACCS Q96QU6 ACCS Homo sapiens Q96QU6
Y2H Array
25416956
Intra ACCS Q96QU6 ACCS Homo sapiens Q96QU6
Y2H Array
32296183
Intra ACCS Q96QU6 ACCS Homo sapiens Q96QU6
Y2H Pooling
16189514
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Thyroid Dyshormonogenesis 5

TDH5

Hypothyroidism, Congenital, Due To Dyshormonogenesis, 5

Thyroid Hormonogenesis, Genetic Defect In, 5

Genetic Defect In Thyroid Hormonogenesis 5

Chdh5

Congenital Hypothyroidism Due To Dyshormonogenesis Type 5

Genetic Defect In Thyroid Hormonogenesis Type 5

Granulomatous Amebic Encephalitis

Granulomatous Amoebic Encephalitis

Acanthamoeba Encephalitis

Acanthamoeba Granulomatous Encephalitis

Granulomatous Amebic Encephalitis Due To Acanthamoeba

Twin-To-Twin Transfusion Syndrome

Twin To Twin Transfusion Syndrome

Twin Twin Transfusion Syndrome

Fetal Blood Loss From Fetal Hemorrhage Into Co-Twin

Fetal Hemorrhage Into Co-Twin

Twin To Twin Transfusion

Twin-To-Twin Blood Transfer

Fetal Transfusion Syndrome

Fetofetal Transfusion Syndrome

Ttts

Feto-Fetal Transfusion Syndrome

Fetofetal Transfusion

Fetus-To-Fetus Placental Transfusion Syndrome

Primary Amebic Meningoencephalitis

Pam

Naegleria Fowleri Infection

Meningoencephalitis Caused By Naegleria Fowleri

Primary Amoebic Meningoencephalitis

Thyroid Dyshormonogenesis 4

Deiodinase Deficiency

TDH4

Iodotyrosine Dehalogenase Deficiency

Thyroid Hormonogenesis, Genetic Defect In, 4

Hypothyroidism, Congenital, Due To Dyshormonogenesis, 4

Genetic Defect In Thyroid Hormonogenesis 4

Chdh4

Congenital Hypothyroidism Due To Dyshormonogenesis Type 4

Genetic Defect In Thyroid Hormonogenesis Type 4

Aplasia Of Lacrimal And Salivary Glands

ALSG

Congenital Absence Of Lacrimal Puncta And Salivary Glands

Xerostomia

Absence Of Salivary Glands

Parotid Aplasia Or Hypoplasia

Congenital Absence Of Lacrimal Puncta Or Salivary Glands

Alsg - [Aplasia Of Lacrimal Or Salivary Glands]

Mucopolysaccharidosis, Type Ix

Mucopolysaccharidosis Type Ix

Hyaluronidase Deficiency

MPS9

Mps Ix

Mucopolysaccharidosis Ix

Mpsix

Mucopolysaccharidosis Type 9

Mucopolysaccharidosis 9

Neonatal Anemia

Anemia Neonatal

Anemia, Neonatal

Anaemia Neonatal

Neonatal Anaemia

Familial Thyroid Dyshormonogenesis

Thyroid Dyshormonogenesis

Familial Dyshormonogenetic Goiter

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ACCS RGD RGD:1309314
Mus musculus ACCS MGD MGI:1919717