2. Gene
  3. ACCS - 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) Gene

ACCS - 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：1-氨基环丙烷-1-羧酸合酶同系物 (无活性)

种属: Homo sapiens

同用名: ACS; PHACS

基因 ID: 84680 | 基因类型: protein coding

关于 ACCS

Cytogenetic location: 11p11.2 Genomic coordinates (GRCh38): 11:44,066,270-44,084,237 (from NCBI)

This gene has 13 transcripts (splice variants), 149 orthologues and 7 paralogues. Ubiquitous expression in spleen (RPKM 11.2), gall bladder (RPKM 7.3) and 25 other tissues.

功能概要

实现相同的蛋白质结合活性。预计参与生物合成过程。 [由基因组资源联盟提供，2022 年 4 月]

Enables identical protein binding activity. Predicted to be involved in biosynthetic process. [provided by Alliance of Genome Resources, Apr 2022]

ACCS 基因产物(2)

mRNA Protein Name
NM_001127219.2 NP_001120691.1 1-aminocyclopropane-1-carboxylate synthase-like protein 1
NM_032592.4 NP_115981.1 1-aminocyclopropane-1-carboxylate synthase-like protein 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
NOT enables 1-aminocyclopropane-1-carboxylate synthase activity IDA
IDA: 通过直接分析推断
11470512 GOA
enables identical protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ACCS 蛋白结构

Aminotran_1_2

Aminotran_1_2: Aminotransferase class I and II (98 - 460)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 501 a.a.
蛋白主名 其他名称

1-aminocyclopropane-1-carboxylate synthase-like protein 1

ACC synthase-like protein 1

ACCS 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
ACCS Q96QU6 UQCRB Homo sapiens P14927
Y2H Prey Pooling
25416956
种属内
ACCS Q96QU6 ACCS Homo sapiens Q96QU6
Y2H Array
31515488
种属内
ACCS Q96QU6 ACCS Homo sapiens Q96QU6
Y2H Prey Pooling
32296183
种属内
ACCS Q96QU6 ACCS Homo sapiens Q96QU6-1
Y2H Array
31515488
种属内
ACCS Q96QU6 ACCS Homo sapiens Q96QU6
Validated Y2H
32296183
种属内
ACCS Q96QU6 ACCS Homo sapiens Q96QU6
Y2H Array
25416956
种属内
ACCS Q96QU6 ACCS Homo sapiens Q96QU6
Y2H Array
32296183
种属内
ACCS Q96QU6 ACCS Homo sapiens Q96QU6
Y2H Pooling
16189514
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Thyroid Dyshormonogenesis 5

TDH5

Hypothyroidism, Congenital, Due To Dyshormonogenesis, 5

Thyroid Hormonogenesis, Genetic Defect In, 5

Genetic Defect In Thyroid Hormonogenesis 5

Chdh5

Congenital Hypothyroidism Due To Dyshormonogenesis Type 5

Genetic Defect In Thyroid Hormonogenesis Type 5
Granulomatous Amebic Encephalitis

Granulomatous Amoebic Encephalitis

Acanthamoeba Encephalitis

Acanthamoeba Granulomatous Encephalitis

Granulomatous Amebic Encephalitis Due To Acanthamoeba
Twin-To-Twin Transfusion Syndrome

Twin To Twin Transfusion Syndrome

Twin Twin Transfusion Syndrome

Fetal Blood Loss From Fetal Hemorrhage Into Co-Twin

Fetal Hemorrhage Into Co-Twin

Twin To Twin Transfusion

Twin-To-Twin Blood Transfer

Fetal Transfusion Syndrome

Fetofetal Transfusion Syndrome

Ttts

Feto-Fetal Transfusion Syndrome

Fetofetal Transfusion

Fetus-To-Fetus Placental Transfusion Syndrome
Primary Amebic Meningoencephalitis

Pam

Naegleria Fowleri Infection

Meningoencephalitis Caused By Naegleria Fowleri

Primary Amoebic Meningoencephalitis
Thyroid Dyshormonogenesis 4

Deiodinase Deficiency

TDH4

Iodotyrosine Dehalogenase Deficiency

Thyroid Hormonogenesis, Genetic Defect In, 4

Hypothyroidism, Congenital, Due To Dyshormonogenesis, 4

Genetic Defect In Thyroid Hormonogenesis 4

Chdh4

Congenital Hypothyroidism Due To Dyshormonogenesis Type 4

Genetic Defect In Thyroid Hormonogenesis Type 4
Aplasia Of Lacrimal And Salivary Glands

ALSG

Congenital Absence Of Lacrimal Puncta And Salivary Glands

Xerostomia

Absence Of Salivary Glands

Parotid Aplasia Or Hypoplasia

Congenital Absence Of Lacrimal Puncta Or Salivary Glands

Alsg - [Aplasia Of Lacrimal Or Salivary Glands]
Mucopolysaccharidosis, Type Ix

Mucopolysaccharidosis Type Ix

Hyaluronidase Deficiency

MPS9

Mps Ix

Mucopolysaccharidosis Ix

Mpsix

Mucopolysaccharidosis Type 9

Mucopolysaccharidosis 9
Neonatal Anemia

Anemia Neonatal

Anemia, Neonatal

Anaemia Neonatal

Neonatal Anaemia
Familial Thyroid Dyshormonogenesis

Thyroid Dyshormonogenesis

Familial Dyshormonogenetic Goiter
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Clinical Phase
生物活性分子 (7)
目录号 产品名 作用方式
纯度 Phase
HY-17641 Olumacostat glasaretil Inhibitor 98.90% Phase 3
HY-16901 Firsocostat Inhibitor 99.96% Phase 2
HY-12942 PF-05175157 Inhibitor 98.46% Phase 2
HY-153367 FHD-609 Inhibitor 99.15% Phase 1
HY-135981 CMS-121 Inhibitor 99.63% Phase 1
HY-107709 MK-4074 Inhibitor 99.04% Phase 1
HY-102066 Utatrectinib Inhibitor 98.72% Phase 1
Pre-clinical Phase
生物活性分子 (34)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-101842 ND-646 Inhibitor 99.13% 否
HY-D0713 7ACC2 Inhibitor 99.62% 否
HY-D0067 7ACC1 Inhibitor 99.71% 否
HY-15259 CP-640186 Inhibitor 99.72% 否
HY-12741 LDN-212320 Activator 99.09% 否
HY-15259A CP-640186 hydrochloride Inhibitor 99.90% 否
HY-147004 A-908292 Inhibitor 99.37% 否
HY-152117 Acetyl-CoA Carboxylase-IN-1 Inhibitor 99.16% 否
HY-100771 PCC0208009 Inhibitor 99.08% 否
HY-E70227 Cathepsin G, human neutrophils 90.00% 否
HY-144701 SABA1 Inhibitor 99.15% 否
HY-120904 AMPK-IN-1 Activator 95.19% 否
HY-16901A Firsocostat (S enantiomer) 98.25% 否
HY-16943 Moiramide B Inhibitor 99.24% 否
HY-19624 NVP-ACC789 Inhibitor 99.52% 否
HY-P10002 EWFW-ACC 95.29% 否
HY-W588256 12-Tridecenoic acid Activator / 否
HY-P10003B iso-VQA-ACC acetate 99.48% 否
HY-127128 Flestolol sulfate Inhibitor / 否
HY-147376 hACC2-IN-1 Inhibitor / 否
HY-147930 ACC1/2-IN-1 Inhibitor / 否
HY-147932 ACC1/2-IN-2 Inhibitor / 否
HY-148684 AMPK activator 10 Activator / 否
HY-151931 JA-ACC / 否
HY-151931S JA-ACC-d3 / 否
HY-161976 ACC1-IN-2 Inhibitor / 否
HY-169008 PROTAC ACC degrader-1 Degrader / 否
HY-169009 (Rac)-Spirotetramat-enol / 否
HY-169010 Pomalidomide-CO-C5-Br / 否
HY-16946 CP-610431 Inhibitor / 否
HY-P10002A EWFW-ACC TFA / 否
HY-P10003 iso-VQA-ACC / 否
HY-P10003A iso-VQA-ACC TFA / 否
HY-RS00146 ACCS Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ACCS RGD RGD:1309314
Mus musculus ACCS MGD MGI:1919717
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