Secoisolariciresinol (Synonyms: (-)-Secoisolariciresinol)

目录号: HY-N6071 纯度: 99.41%: FAQs
Data Sheet SDS COA 产品使用指南

摩尔计算器

Secoisolariciresinol 是一种木脂素，属于苯丙素类。

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Secoisolariciresinol Chemical Structure

CAS No. : 29388-59-8

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规格	价格	是否有货
1 mg	￥1000	In-stock
5 mg	￥2100	In-stock
10 mg	￥3100	In-stock
25 mg	￥5600	In-stock
50 mg		询价
100 mg		询价

or 大包装询价

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Customer Review

Other Forms of Secoisolariciresinol:

Secoisolariciresinol diglucoside In-stock
(R,R)-Secoisolariciresinol diglucoside In-stock
seco-Isolariciresinol Diglucoside 询价
Secoisolariciresinol Monoglucoside 询价

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生物活性
纯度 & 产品资料
参考文献

生物活性

Secoisolariciresinol is a lignan, a type of phenylpropanoids.

细胞效力
(Cellular Effect)

Cell Line	Type	Value	Description	References
A549	IC₅₀	> 110.4 μM Compound: 7	Cytotoxicity against human A549 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human A549 cells after 48 hrs by sulforhodamine B assay	[PMID: 21958542]
A549	IC₅₀	> 30 μM Compound: 11	Anticancer activity against human A549 cells by SRB assay Anticancer activity against human A549 cells by SRB assay	[PMID: 21420296]
A549	IC₅₀	> 40 μg/mL Compound: 1	Cytotoxicity against human A549 cells after 48 hrs by SRB assay Cytotoxicity against human A549 cells after 48 hrs by SRB assay	[PMID: 18603435]
B16-F1	IC₅₀	> 40 μg/mL Compound: 1	Cytotoxicity against mouse B16F1 cells after 48 hrs by SRB assay Cytotoxicity against mouse B16F1 cells after 48 hrs by SRB assay	[PMID: 18603435]
B16-F10	IC₅₀	> 110.4 μM Compound: 7	Cytotoxicity against mouse B16F10 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against mouse B16F10 cells after 48 hrs by sulforhodamine B assay	[PMID: 21958542]
BC	IC₅₀	> 5 μg/mL Compound: Secoisolariciresinol	Cytotoxicity against human BC cells by colorimetric method Cytotoxicity against human BC cells by colorimetric method	[PMID: 16038539]
HCT-15	IC₅₀	> 110.4 μM Compound: 7	Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay	[PMID: 21958542]
HT-1080	EC₅₀	5.9 μg/mL Compound: 5	Antiproliferative activity against human HT1080 cells by MTT assay Antiproliferative activity against human HT1080 cells by MTT assay	[PMID: 12444707]
KB	IC₅₀	> 5 μg/mL Compound: Secoisolariciresinol	Cytotoxicity against human KB cells by colorimetric method Cytotoxicity against human KB cells by colorimetric method	[PMID: 16038539]
NCI-H187	IC₅₀	> 5 μg/mL Compound: Secoisolariciresinol	Cytotoxicity against human NCI-H187 cells by colorimetric method Cytotoxicity against human NCI-H187 cells by colorimetric method	[PMID: 16038539]
RAW264.7	IC₅₀	> 100 μM Compound: 4;SI	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced PGE2 production pretreated for 1 hr followed by LPS addition measured after 24 hrs Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced PGE2 production pretreated for 1 hr followed by LPS addition measured after 24 hrs	[PMID: 29102229]
RAW264.7	IC₅₀	> 200 μM Compound: 4;SI	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production measured after 24 hrs by Griess assay Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production measured after 24 hrs by Griess assay	[PMID: 29102229]
RAW264.7	IC₅₀	0.172 mM Compound: 16	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs	[PMID: 18986199]
RAW264.7	IC₅₀	132 μM Compound: Secoisolariciresinol	Antiinflammatory activity in mouse RAW264.7 cells assessed as decrease in IFN-gamma and LPS-induced nitric oxide production after 24 hrs by ELISA Antiinflammatory activity in mouse RAW264.7 cells assessed as decrease in IFN-gamma and LPS-induced nitric oxide production after 24 hrs by ELISA	[PMID: 35998343]
SK-MEL-2	IC₅₀	> 110.4 μM Compound: 7	Cytotoxicity against human SK-MEL-2 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human SK-MEL-2 cells after 48 hrs by sulforhodamine B assay	[PMID: 21958542]
SK-MEL-2	IC₅₀	> 40 μg/mL Compound: 1	Cytotoxicity against human SK-MEL-2 cells after 48 hrs by SRB assay Cytotoxicity against human SK-MEL-2 cells after 48 hrs by SRB assay	[PMID: 18603435]
SK-MEL-2	IC₅₀	21.47 μM Compound: 11	Anticancer activity against human SK-MEL-2 cells by SRB assay Anticancer activity against human SK-MEL-2 cells by SRB assay	[PMID: 21420296]
SK-OV-3	IC₅₀	> 110.4 μM Compound: 7	Cytotoxicity against human SKOV3 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human SKOV3 cells after 48 hrs by sulforhodamine B assay	[PMID: 21958542]
SK-OV-3	IC₅₀	> 30 μM Compound: 11	Anticancer activity against human SKOV3 cells by SRB assay Anticancer activity against human SKOV3 cells by SRB assay	[PMID: 21420296]
XF498	IC₅₀	18.75 μM Compound: 11	Anticancer activity against human XF498 cells by SRB assay Anticancer activity against human XF498 cells by SRB assay	[PMID: 21420296]

Clinical Trial

分子量

362.42

Formula

C₂₀H₂₆O₆

CAS 号

29388-59-8

性状

固体

颜色

White to off-white

中文名称

开环异落叶松树脂酚

结构分类

初始来源

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据

细胞实验：

DMSO 中的溶解度 : 100 mg/mL (275.92 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	2.7592 mL	13.7961 mL	27.5923 mL
5 mM	0.5518 mL	2.7592 mL	5.5185 mL
10 mM	0.2759 mL	1.3796 mL	2.7592 mL

查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

摩尔计算器
稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

浓度 _(start)

体积 _(start)

浓度 _(final)

体积 _(final)

动物溶解方案计算器

请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

每只动物的给药体积

μL

动物数量

只

由于实验过程有损耗，建议您多配一只动物的量

计算结果

工作液所需浓度 : mg/mL

纯度 & 产品资料

纯度: 99.41%

选择批次：

Data Sheet (601 KB) SDS (393 KB)

COA (192 KB) RP-HPLC (205 KB)

产品使用指南 (1538 KB)

参考文献

[1]. Eva Tavčar Benković, et al. Identification, in vitro and in vivo Antioxidant Activity, and Gastrointestinal Stability of Lignans from Silver Fir (Abies alba) Wood Extract. Journal of Wood Chemistry and Technology. 2017 Jan, 467-477.

Secoisolariciresinol 相关分类

完整储备液配制表

可选溶剂	浓度溶剂体积质量	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.7592 mL	13.7961 mL	27.5923 mL	68.9807 mL
	5 mM	0.5518 mL	2.7592 mL	5.5185 mL	13.7961 mL
	10 mM	0.2759 mL	1.3796 mL	2.7592 mL	6.8981 mL
	15 mM	0.1839 mL	0.9197 mL	1.8395 mL	4.5987 mL
	20 mM	0.1380 mL	0.6898 mL	1.3796 mL	3.4490 mL
	25 mM	0.1104 mL	0.5518 mL	1.1037 mL	2.7592 mL
	30 mM	0.0920 mL	0.4599 mL	0.9197 mL	2.2994 mL
	40 mM	0.0690 mL	0.3449 mL	0.6898 mL	1.7245 mL
	50 mM	0.0552 mL	0.2759 mL	0.5518 mL	1.3796 mL
	60 mM	0.0460 mL	0.2299 mL	0.4599 mL	1.1497 mL
	80 mM	0.0345 mL	0.1725 mL	0.3449 mL	0.8623 mL
	100 mM	0.0276 mL	0.1380 mL	0.2759 mL	0.6898 mL

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Secoisolariciresinol29388-59-8(-)-Secoisolariciresinol开环异落叶松树脂酚OthersInhibitorinhibitorinhibit

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

Secoisolariciresinol (Synonyms: (-)-Secoisolariciresinol)

Customer Review

Other Forms of Secoisolariciresinol: