2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Reactive Oxygen Species
  4. Allyl methyl trisulfide

Allyl methyl trisulfide 是一种挥发性有机化合物，是大蒜(Allium sativum L.)精油的成分，具有抗菌、抗氧化以及抗肿瘤活性等。

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Allyl methyl trisulfide Chemical Structure

Allyl methyl trisulfide Chemical Structure

CAS No. : 34135-85-8

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Allyl methyl trisulfide 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Allyl methyl trisulfide is a volatile organic compound and a component of garlic (Allium sativum L.) essential oil, which has antibacterial, antioxidant and antitumor activities[1].

体内研究
(In Vivo)

Allyl methyl trisulfide(AMS)(50-200 mg/kg, orally, daily, 30 days)在 STZ 诱导的高血糖大鼠中具有保护功效。可以导致血糖和促炎标志物 TNF-α、IL-6、NF-κB p65 表达显著降低，而血浆胰岛素水平升高，并且具有一定的抗氧化活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Wistar rats (170-190 g)[1]
Dosage: 50, 100 and 200 mg/kg
Administration: orally in the daily morning for 30 days
Result: Enhanced body, organ weight and reduced food, water intake.
Dose-dependently decreased plasma glucose and enhanced insulin.
Attenuated the oxidative stress stimulated by STZ in hepatocytes.
Increased activity of hepatotoxicity markers AST, ALT and ALP.
Significantly downregulated the expression of pro-inflammatory proteins, cytokines (TNF-α and IL-6) and transcription factors (NF-κB p65).
分子量

152.30

Formula

C4H8S3
CAS 号
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Allyl methyl trisulfide 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Allyl methyl trisulfide34135-85-8Reactive Oxygen Speciesorganic compoundgarlicantibacterialantioxidantantitumorInhibitorinhibitorinhibit

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