2. 一站式药筛
  3. 化合物库
  4. 生物活性化合物库系列
  5. 信号通路化合物库系列
  6. 线粒体自噬化合物库
线粒体自噬化合物库 - Mitophagy Compound Library

Cat. No.: HY-L180

线粒体自噬是指细胞通过自噬机制选择性地包裹和降解受损的线粒体，从而维持线粒体和细胞内稳态。从线粒体自噬的概念提出以来就受到了研究者们的广泛关注。目前的研究表明，线粒体自噬的发生机制通常可以分为两类：泛素依赖途径和非泛素依赖途径。此外，线粒体自噬是与神经退行性疾病、心血管疾病、癌症、代谢性疾病等临床疾病发生相关的研究热点。因此，开展基于线粒体自噬的高通量筛选，可高效地筛选出与疾病发生息息相关的化合物，并解析其机制。

MCE 可以提供 604 种线粒体自噬相关化合物，可以用于癌症、免疫、感染等热门研究领域药物开发以及机制研究。

我们将在明确您的产品用途后，向符合资质的客户通过定制合成服务的方式提供 MCE 线粒体自噬化合物库，我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中，591 个产品以 10 mM 浓度提供，11 个产品以 2 mM 浓度提供，2 个产品以 3 mg/mL 浓度提供。

溶液包装中，我们对于溶液状态稳定且溶解度不低于 10 mM 的产品，提供 10 mM 溶液；对于溶液状态稳定且溶解度介于 2~10 mM 的产品，我们提供 2 mM 溶液；对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品，我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 604 bioactive compounds for high throughput screening (HTS) and high content screening (HCS).

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 604 small molecules related to mitophagy as pre-dissolved Solutions or Solid
Solution: 591 compounds supplied in 10 mM solution, 11 compounds supplied in 2 mM solution, 2 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

化合物库组成

Composition

PARP (14)

Akt (13)

ULK (12)

COX (11)

IKK (10)

p62 (9)

Ras (8)

PI3K (6)

CDK (5)

HIV (5)

JNK (5)

mTOR (5)

AMPK (4)

EGFR (4)

HSP (4)

Wnt (4)

AP-1 (3)

ERK (3)

MMP (3)

SOD (3)

STAT (3)

HBV (2)

HSV (2)

IAP (2)

JAK (2)

PKC (2)

PPAR (2)

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  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式（固体或溶液）
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联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称：
    Mitophagy Compound Library
    目录号：
    HY-L180
    需求量：

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