2. Membrane Transporter/Ion Channel
  3. Aquaporin
  4. AQP3-IN-1

AQP3-IN-1 (compounds 3) 是一种 AQP3 抑制剂，IC50 值为 8.91 μM。AQP3-IN-1 抑制黑色素瘤细胞的细胞增殖。

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AQP3-IN-1 Chemical Structure

AQP3-IN-1 Chemical Structure

CAS No. : 198711-19-2

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AQP3-IN-1 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AQP3-IN-1 (compounds 3) is an AQP3 inhibitor with a IC50 value of 8.91 μM. AQP3-IN-1 inhibits cell proliferation of melanoma cells[1].

IC50 & Target

AQP3

8.91 μM (IC50)

体外研究
(In Vitro)

AQP3-IN-1 (compounds 3) (5 μM，30分钟) 抑制过表达 AQP3 细胞通透性和红细胞甘油渗透性，但不影响其透水性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

AQP3-IN-1 相关抗体:

Cell Viability Assay[1]

Cell Line: MNT-1, A375 and HEK-293T
Concentration: 2.5-10 μM
Incubation Time: 24 h
Result: Had no toxic effect on MNT-1 and A375 cells and did not affect cell viability.

Cell Migration Assay [1]

Cell Line: MNT-1, A375
Concentration: 5 μM
Incubation Time: 0, 9, 24 h
Result: Inhibited melanoma cell adhesion, proliferation, and migration.
分子量

437.08

Formula

C11H9AuCl2N2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AQP3-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AQP3-IN-1198711-19-2AquaporinAQPPeroxiporin activityMelanoma cellsAnticancerMNT-1A375AQP3Inhibitorinhibitorinhibit

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