1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Deacetyldiltiazem

Deacetyldiltiazem  (Synonyms: 去乙酰地尔硫卓)

目录号: HY-126182
产品使用指南

Deacetyldiltiazem是一种代谢物,具有冠状血管扩张活性。Deacetyldiltiazem在服用Diltiazem的个体的血浆中存在。Deacetyldiltiazem的去乙酰化酶活性主要由大鼠的Ces2a酶催化。Deacetyldiltiazem的体外实验显示其与大鼠肝微粒的Km值相似,表现出高效的去乙酰化酶活性。Deacetyldiltiazem的研究有助于理解不同物种之间的化合物代谢动力学差异。

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Deacetyldiltiazem Chemical Structure

Deacetyldiltiazem Chemical Structure

CAS No. : 42399-40-6

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Deacetyldiltiazem is a metabolite with coronary vasodilator activity. Deacetyldiltiazem is present in the plasma of individuals taking Diltiazem. The deacetylase activity of deacetyldiltiazem is mainly catalyzed by the rat Ces2a enzyme. In vitro experiments of deacetyldiltiazem showed that its Km value was similar to that of rat liver microsomes, showing efficient deacetylase activity. The study of deacetyldiltiazem helps to understand the differences in the metabolic kinetics of compounds between different species[1].

分子量

372.48

Formula

C20H24N2O3S

CAS 号
中文名称

去乙酰地尔硫卓

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Deacetyldiltiazem
目录号:
HY-126182
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