VTI1B - vesicle transport through interaction with t-SNAREs 1B Gene

中文名称：通过与 t-SNARE 1B 的相互作用进行囊泡运输

种属: Homo sapiens

同用名: VTI1; VTI2; VTI1L; v-SNARE; vti1-rp1; VTI1-LIKE

基因 ID: 10490 | 基因类型: protein coding

关于 VTI1B

Cytogenetic location: 14q24.1 Genomic coordinates (GRCh38): 14:67,647,085-67,674,632 (from NCBI)

This gene has 6 transcripts (splice variants), 201 orthologues and 2 paralogues. Ubiquitous expression in fat (RPKM 68.1), kidney (RPKM 45.6) and 25 other tissues.

功能概要

启用 SNARE 结合活性和氯离子通道抑制剂活性。参与调节蛋白质在质膜上的定位。位于多种细胞成分中，包括内体膜；溶酶体膜；和细胞质的核周区。 [由基因组资源联盟提供，2022 年 4 月]

Enables SNARE binding activity and Chloride Channel Inhibitor activity. Involved in regulation of protein localization to plasma membrane. Located in several cellular components, including endosome membrane; lysosomal membrane; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

VTI1B 基因产物(1)

mRNA	Protein	Name
NM_006370.3	NP_006361.1	vesicle transport through interaction with t-SNAREs homolog 1B

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables SNARE binding	IDA IDA: 通过直接分析推断	24550300	GOA
enables chloride channel inhibitor activity	IDA IDA: 通过直接分析推断	18570918	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	16189514	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
NOT involved in autophagosome maturation	IMP IMP: 通过突变表型推断	23217709	GOA
involved in regulation of protein localization to plasma membrane	IDA IDA: 通过直接分析推断	18570918	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in Golgi apparatus	IDA IDA: 通过直接分析推断	19224922	GOA
located in early endosome membrane	IDA IDA: 通过直接分析推断	18033301	GOA
located in late endosome membrane	IDA IDA: 通过直接分析推断	18033301	GOA
located in lysosomal membrane	IDA IDA: 通过直接分析推断	18033301	GOA
located in perinuclear region of cytoplasm	IDA IDA: 通过直接分析推断	18570918	GOA
located in recycling endosome	IDA IDA: 通过直接分析推断	18570918	GOA
located in recycling endosome membrane	IDA IDA: 通过直接分析推断	18033301	GOA
located in vesicle	IDA IDA: 通过直接分析推断	18570918	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

VTI1B 蛋白结构

V-SNARE

V-SNARE_C

0
100
200
232 a.a.

蛋白主名

其他名称

vesicle transport through interaction with t-SNAREs homolog 1B

vesicle transport v-SNARE protein Vti1-like 1

VTI1B 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	VTI1B	Q9UEU0	KRTAP10-7	Homo sapiens	P60409	Y2H Array	25416956
种属内	VTI1B	Q9UEU0	LDLRAD1	Homo sapiens	Q5T700	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	LDLRAD1	Homo sapiens	Q5T700	Y2H Array	31515488
种属内	VTI1B	Q9UEU0	LDLRAD1	Homo sapiens	Q5T700	Validated Y2H	25416956
种属内	VTI1B	Q9UEU0	LDLRAD1	Homo sapiens	Q5T700	Y2H Array	25416956
种属内	VTI1B	Q9UEU0	LDLRAD1	Homo sapiens	Q5T700	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	TRIM59	Homo sapiens	Q8IWR1	Y2H Array	25416956
种属内	VTI1B	Q9UEU0	TRIM59	Homo sapiens	Q8IWR1	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	TRIM59	Homo sapiens	Q8IWR1	Y2H Prey Pooling	25416956
种属内	VTI1B	Q9UEU0	TRIM59	Homo sapiens	Q8IWR1	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	TRIM59	Homo sapiens	Q8IWR1	Y2H Array	31515488
种属内	VTI1B	Q9UEU0	JAGN1	Homo sapiens	Q8N5M9	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	GPX8	Homo sapiens	Q8TED1	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	GPX8	Homo sapiens	Q8TED1	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	STX2	Homo sapiens	P32856-2	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	STX2	Homo sapiens	P32856-2	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	PTPN5	Homo sapiens	P54829	Y2H Array	25416956
种属内	VTI1B	Q9UEU0	PTPN5	Homo sapiens	P54829	Y2H Prey Pooling	25416956
种属内	VTI1B	Q9UEU0	PTPN5	Homo sapiens	P54829	Validated Y2H	25416956
种属内	VTI1B	Q9UEU0	ASGR2	Homo sapiens	P07307-3	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	ASGR2	Homo sapiens	P07307-3	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	CD46	Homo sapiens	P15529-3	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	CD46	Homo sapiens	P15529-3	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	AQP6	Homo sapiens	Q13520	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	AQP6	Homo sapiens	Q13520	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	CRB3	Homo sapiens	Q9BUF7-2	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	CRB3	Homo sapiens	Q9BUF7-2	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	SLC35C2	Homo sapiens	Q9NQQ7-3	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	SLC35C2	Homo sapiens	Q9NQQ7-3	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	RNASEK	Homo sapiens	Q6P5S7	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	RNASEK	Homo sapiens	Q6P5S7	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	FCGR1A	Homo sapiens	P12314	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	FCGR1A	Homo sapiens	P12314	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	MANBAL	Homo sapiens	Q9NQG1	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	MANBAL	Homo sapiens	Q9NQG1	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	SLC16A7	Homo sapiens	O60669	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	SLC16A7	Homo sapiens	O60669	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	STX1A	Homo sapiens	Q16623	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	STX1A	Homo sapiens	Q16623	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	TMEM51	Homo sapiens	Q9NW97	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	TMEM51	Homo sapiens	Q9NW97	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	STX8	Homo sapiens	Q9UNK0	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	STX8	Homo sapiens	Q9UNK0	Anti Tag CoIP	33961781
种属内	VTI1B	Q9UEU0	STX8	Homo sapiens	Q9UNK0	Anti Tag CoIP	28514442
种属内	VTI1B	Q9UEU0	STX8	Homo sapiens	Q9UNK0	Validated Y2H	32296183
种属内	VTI1B	Q9UEU0	STX8	Homo sapiens	Q9UNK0	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	STX8	Homo sapiens	Q9UNK0	Anti Tag CoIP	35271311
种属内	VTI1B	Q9UEU0	STX4	Homo sapiens	Q12846	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	STX4	Homo sapiens	Q12846	Y2H Array	25416956
种属内	VTI1B	Q9UEU0	STX4	Homo sapiens	Q12846	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	KASH5	Homo sapiens	Q8N6L0	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	KASH5	Homo sapiens	Q8N6L0	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	REEP4	Homo sapiens	Q9H6H4	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	REEP4	Homo sapiens	Q9H6H4	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	CD79A	Homo sapiens	P11912	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	CD79A	Homo sapiens	P11912	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	ERGIC3	Homo sapiens	Q9Y282	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	ERGIC3	Homo sapiens	Q9Y282	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	ERGIC3	Homo sapiens	Q9Y282	Validated Y2H	32296183
种属内	VTI1B	Q9UEU0	TMEM14B	Homo sapiens	Q9NUH8	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	TMEM14B	Homo sapiens	Q9NUH8	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	TMEM234	Homo sapiens	Q8WY98	Y2H Prey Pooling	32296183
种属内	VTI1B	Q9UEU0	TMEM234	Homo sapiens	Q8WY98	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	KLRC1	Homo sapiens	P26715	Y2H Array	32296183
种属内	VTI1B	Q9UEU0	KLRC1	Homo sapiens	P26715	Y2H Prey Pooling	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Hemophagocytic Lymphohistiocytosis, Familial, 4

Familial Hemophagocytic Lymphohistiocytosis 4	FHL4
Hplh4	Hlh4
Lymphohistiocytosis, Hemophagocytic, Familial, Type 4

Tetanus

Lockjaw	Clostridial Tetanus
Infection Due To Clostridium Tetani	Lock-Jaw

Hermansky-Pudlak Syndrome

Hps	Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial Cells
Hermanski-Pudlak Syndrome	Hermansky Pudlak Syndrome
Platelet Storage Pool Deficiency

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS15723	VTI1B Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	VTI1B	MGD	MGI:1855688
Macaca mulatta	VTI1B	VGNC	VGNC:99341
Rattus norvegicus	VTI1B	RGD	RGD:2323682
Felis catus	VTI1B	VGNC	VGNC:80781
Bos taurus	VTI1B	VGNC	VGNC:36849
Canis familiaris	VTI1B	VGNC	VGNC:48317

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

VTI1B - vesicle transport through interaction with t-SNAREs 1B Gene

关于 VTI1B

功能概要

VTI1B 基因产物(1)

VTI1B 蛋白结构

VTI1B 蛋白互作信息

关联疾病

直系同源

热门区域

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VTI1B - vesicle transport through interaction with t-SNAREs 1B Gene

关于 VTI1B

功能概要

VTI1B 基因产物(1)

VTI1B 蛋白结构

VTI1B 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z