Il2 - interleukin 2 Gene

中文名称：白细胞介素 2

种属: Rattus norvegicus

关于 Il2

功能概要

该基因编码的蛋白可启动碳水化合物结合活动；糖脂结合活性；和信号受体结合活性。参与多个过程，包括 T 细胞活化的正调节；蛋白激酶C激活G蛋白偶联受体信号通路；和蛋白质磷酸化的调节。位于细胞外空间。用于研究膀胱炎。过敏性鼻炎的生物标志物；结直肠癌；和舌鳞状细胞癌。该基因的人类直系同源物与多种疾病有关，包括 Takayasu 动脉炎；听觉系统疾病（多种）；自身免疫性疾病（多种）；癌（多发性）；和神经退行性疾病（多种）。与人 IL2（白细胞介素 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables carbohydrate binding activity; glycosphingolipid binding activity; and signaling receptor binding activity. Involved in several processes, including positive regulation of T cell activation; protein kinase C-activating G protein-coupled receptor signaling pathway; and regulation of protein phosphorylation. Located in extracellular space. Used to study cystitis. Biomarker of allergic rhinitis; colorectal carcinoma; and tongue squamous cell carcinoma. Human ortholog(s) of this gene implicated in several diseases, including Takayasu's arteritis; auditory system disease (multiple); autoimmune disease (multiple); carcinoma (multiple); and neurodegenerative disease (multiple). Orthologous to human IL2 (interleukin 2). [provided by Alliance of Genome Resources, Apr 2022]