2. Gene
  3. ANKRD28 - ankyrin repeat domain 28 Gene

ANKRD28 - ankyrin repeat domain 28 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：锚蛋白重复结构域 28

种属: Homo sapiens

同用名: PITK; FAP79; CFAP79; PPP1R65

基因 ID: 23243 | 基因类型: protein coding

关于 ANKRD28

Cytogenetic location: 3p25.1 Genomic coordinates (GRCh38): 3:15,667,236-15,859,814 (from NCBI)

This gene has 16 transcripts (splice variants), 282 orthologues and 3 paralogues. Ubiquitous expression in bone marrow (RPKM 14.3), testis (RPKM 10.7) and 25 other tissues.

功能概要

预计位于胞质溶胶和核质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ANKRD28 基因产物(12)

mRNA Protein Name
NM_001195098.1 NP_001182027.1 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform b
NM_001195099.2 NP_001182028.1 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform b
NM_001349277.2 NP_001336206.1 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform c
NM_001349278.2 NP_001336207.1 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform d
NM_001349279.2 NP_001336208.1 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform e
NM_001349280.1 NP_001336209.1 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform f
NM_001349281.2 NP_001336210.1 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform f
NM_001349282.2 NP_001336211.1 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform f
NM_001349283.2 NP_001336212.1 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform b
NM_001349284.2 NP_001336213.1 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform g
NM_001349285.2 NP_001336214.1 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform h
NM_015199.4 NP_056014.2 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform a
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18186651 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ANKRD28 蛋白结构

Ank_2

Ank_2: Ankyrin repeats (3 copies) (12 - 104)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (108 - 170)

Ank

Ank: Ankyrin repeat (176 - 204)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (210 - 301)

Ank

Ank: Ankyrin repeat (338 - 365)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (376 - 467)

Ank

Ank: Ankyrin repeat (471 - 503)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (538 - 613)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (617 - 683)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (690 - 778)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (792 - 886)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (894 - 972)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1053 a.a.
蛋白主名 其他名称

serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

PP6-ARS-A

ANKRD28 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
ANKRD28 O15084 KCNV2 Homo sapiens Q8TDN2
Validated Y2H
32296183
种属内
ANKRD28 O15084 PIBF1 Homo sapiens Q4G0R1
Validated Y2H
32296183
种属内
ANKRD28 O15084 MGC50722 Homo sapiens Q8IVT4
Validated Y2H
32296183
种属内
ANKRD28 O15084 PTRH1 Homo sapiens Q86Y79
Validated Y2H
32296183
种属内
ANKRD28 O15084 YTHDC1 Homo sapiens Q96MU7
Validated Y2H
32296183
种属内
ANKRD28 O15084 EIF3D Homo sapiens O15371
Validated Y2H
32296183
种属内
ANKRD28 O15084 PPP6R3 Homo sapiens Q5H9R7
Anti Tag CoIP
24255178
种属内
ANKRD28 O15084 PPP6R3 Homo sapiens Q5H9R7
Anti Tag CoIP
35271311
种属内
ANKRD28 O15084 PPP6R3 Homo sapiens Q5H9R7
GMS
18186651
种属内
ANKRD28 O15084 PPP6R2 Homo sapiens O75170
Anti Tag CoIP
24255178
种属内
ANKRD28 O15084 PPP6R2 Homo sapiens O75170
BioID
24255178
种属内
ANKRD28 O15084 PPP6R2 Homo sapiens O75170
Anti Tag CoIP
35271311
种属内
ANKRD28 O15084 PPP6R1 Homo sapiens Q9UPN7
Anti Tag CoIP
18186651
种属内
ANKRD28 O15084 PPP6R1 Homo sapiens Q9UPN7
GMS
18186651
种属内
ANKRD28 O15084 PPP6R1 Homo sapiens Q9UPN7
BioID
24255178
种属内
ANKRD28 O15084 PPP6R1 Homo sapiens Q9UPN7
Anti Tag CoIP
35271311
种属内
ANKRD28 O15084 PPP6R1 Homo sapiens Q9UPN7
Anti Tag CoIP
24255178
种属内
ANKRD28 O15084 PPP6C Homo sapiens O00743
BioID
24255178
种属内
ANKRD28 O15084 PPP6C Homo sapiens O00743
Anti Tag CoIP
24255178
种属内
ANKRD28 O15084 PPP6C Homo sapiens O00743
Anti Tag CoIP
18186651
种属内
ANKRD28 O15084 PPP6C Homo sapiens O00743
Anti Tag CoIP
35271311
种属内
ANKRD28 O15084 PPP6C Homo sapiens O00743
GMS
18186651
种属内
ANKRD28 O15084 GADD45GIP1 Homo sapiens Q8TAE8
Validated Y2H
32296183
种属内
ANKRD28 O15084 TNKS2 Homo sapiens Q9H2K2
Y2H Fragment Pooling
23414517
种属内
ANKRD28 O15084 DOCK1 Homo sapiens Q14185
Anti Tag CoIP
19118547
种属内
ANKRD28 O15084 INCA1 Homo sapiens Q0VD86
Validated Y2H
32296183
种属内
ANKRD28 O15084 THAP7 Homo sapiens Q9BT49
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Urethra Clear Cell Adenocarcinoma

Clear Cell Adenocarcinoma Of The Urethra

Urethral Clear Cell Adenocarcinoma
Urethra Adenocarcinoma

Adenocarcinoma Of The Urethra

Urethral Adenocarcinoma
Urethra Cancer

Cancer Of Urethra

Malignant Tumour Of Urethra

Malignant Urethral Neoplasm

Urethral Ca
Apolipoprotein C-Iii Deficiency

Hyperalphalipoproteinemia 2

HALP2
Cardiomyopathy, Familial Hypertrophic, 2

Hypertrophic Cardiomyopathy 2

CMH2

Cardiomyopathy, Hypertrophic, 2

Cardiomyopathy Familial Hypertrophic 2

Cardiomyopathy, Familial Hypertrophic 2

Cardiomyopathy, Hypertrophic, Familial, Type 2
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00721 ANKRD28 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus ANKRD28 VGNC VGNC:59805
Rattus norvegicus ANKRD28 RGD RGD:1559931
Canis familiaris ANKRD28 VGNC VGNC:37893
Bos taurus ANKRD28 VGNC VGNC:25920
Mus musculus ANKRD28 MGD MGI:2145661
Macaca mulatta ANKRD28 VGNC VGNC:69731
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