Akt3 - thymoma viral proto-oncogene 3 Gene

中文名称：胸腺瘤病毒原癌基因3

种属: Mus musculus

同用名: Nmf350; D930002M15Rik

关于 Akt3

功能概要

预测该基因编码的蛋白可启动 ATP 绑定活动；蛋白激酶 C 结合活性；和蛋白丝氨酸/苏氨酸激酶活性。参与血管生成的正向调节和动脉形态发生的正向调节。作用于多个过程的上游或内部，包括大脑形态发生； TOR 信号的正调控；和细胞大小的正调节。预测位于质膜中。以多种结构表达，包括泌尿生殖系统；肌肉组织；神经系统;视网膜；和皮肤。与结肠癌有关的该基因的人类直系同源物；胶质母细胞瘤;前列腺癌；前列腺癌;和肾细胞癌。与人类 AKT3（AKT 丝氨酸/苏氨酸激酶 3）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable ATP binding activity; protein kinase C binding activity; and protein serine/threonine kinase activity. Involved in positive regulation of angiogenesis and positive regulation of artery morphogenesis. Acts upstream of or within several processes, including brain morphogenesis; positive regulation of TOR signaling; and positive regulation of cell size. Predicted to be located in plasma membrane. Is expressed in several structures, including genitourinary system; musculature; nervous system; retina; and skin. Human ortholog(s) of this gene implicated in colon cancer; glioblastoma; prostate adenocarcinoma; prostate cancer; and renal cell carcinoma. Orthologous to human Akt3 (Akt serine/threonine kinase 3). [provided by Alliance of Genome Resources, Apr 2022]