1. Gene
  2. KLF3 - KLF transcription factor 3 Gene

KLF3 - KLF transcription factor 3 Gene

中文名称:KLF 转录因子 3

种属: Homo sapiens

同用名: BKLF

基因 ID: 51274 | 基因类型: protein coding

关于 KLF3

Cytogenetic location: 4p14 Genomic coordinates (GRCh38): 4:38,664,199-38,701,517 (from NCBI)

This gene has 3 transcripts (splice variants), 194 orthologues and 22 paralogues. Ubiquitous expression in colon (RPKM 22.1), gall bladder (RPKM 19.2) and 25 other tissues.

功能概要

启用序列特异性双链 DNA 结合活性。预计参与 RNA 聚合酶 II 的转录调控。位于核质中。 [由基因组资源联盟提供,2022 年 4 月]

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

KLF3 基因产物(1)

mRNA Protein Name
NM_016531.6 NP_057615.3 Krueppel-like factor 3
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
24722188 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: 通过直接分析推断
28473536 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

KLF3 蛋白结构

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (276 - 293)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (307 - 331)

  • 0
  • 100
  • 200
  • 300
  • 345 a.a.
蛋白主名 其他名称

Krueppel-like factor 3

CACCC-box-binding protein BKLF

关联疾病

疾病名称 别名
Cutaneous Adenocystic Carcinoma

Adenoid Cystic Eccrine Carcinoma

Adenoid Cystic Carcinoma Of The Skin

Adenoid Cystic Eccrine Carcinoma Of Skin

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta KLF3 VGNC VGNC:73840
Rattus norvegicus KLF3 RGD RGD:1593290
Felis catus KLF3 VGNC VGNC:63134
Canis familiaris KLF3 VGNC VGNC:42436
Mus musculus KLF3 MGD MGI:1342773
Bos taurus KLF3 VGNC VGNC:30630