PPP2R5A - protein phosphatase 2 regulatory subunit B'alpha Gene

中文名称：蛋白磷酸酶 2 调节亚基 B'alpha

种属: Homo sapiens

同用名: B56A; PR61A; B56alpha

关于 PPP2R5A

功能概要

该基因的产物属于磷酸酶 2A 调节亚基 B 家族。蛋白磷酸酶 2A 是四种主要的 Ser/Thr 磷酸酶之一，与细胞生长和分裂的负调控有关。它由一个共同的异聚核心酶组成，该核心酶由一个催化亚基和一个恒定的调节亚基组成，与多种调节亚基相关联。 B 调节亚基可能调节底物选择性和催化活性。该基因编码调节亚基 B56 亚家族的 alpha 异构体。已发现该基因编码不同亚型的替代转录变体。[RefSeq 提供，2010 年 12 月]

The product of this gene belongs to the Phosphatase 2A regulatory subunit B family. Protein Phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core Enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. Alternative transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]