YOD1 - YOD1 deubiquitinase Gene

中文名称：YOD1 去泛素化酶

种属: Homo sapiens

同用名: DUBA8; OTUD2; PRO0907

关于 YOD1

功能概要

蛋白质泛素化控制许多细胞内过程，包括细胞周期进程、转录激活和信号转导。这个动态过程涉及泛素结合酶和去泛素化酶，添加和去除泛素。去泛素化酶是半胱氨酸蛋白酶，可特异性地从泛素缀合的蛋白质底物上切割泛素。该基因编码的蛋白质属于以卵巢肿瘤 (OTU) 结构域为特征的 DUB 亚家族。可变剪接导致多个转录本变体。[RefSeq 提供，2013 年 1 月]

Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating Enzymes and deubiquitinating Enzymes, adds and removes ubiquitin. Deubiquitinating Enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. The protein encoded by this gene belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]