2. Gene
  3. TBRG4 - transforming growth factor beta regulator 4 Gene

TBRG4 - transforming growth factor beta regulator 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：转化生长因子 β 调节因子 4

种属: Homo sapiens

同用名: CPR2; FASTKD4

基因 ID: 9238 | 基因类型: protein coding

关于 TBRG4

Cytogenetic location: 7p13 Genomic coordinates (GRCh38): 7:45,100,100-45,111,697 (from NCBI)

This gene has 17 transcripts (splice variants), 195 orthologues and 5 paralogues. Ubiquitous expression in testis (RPKM 18.2), duodenum (RPKM 14.9) and 25 other tissues.

功能概要

启用 RNA 结合活性。参与线粒体 mRNA 加工和线粒体 mRNA 稳定性的调节。位于线粒体基质中。 [由基因组资源联盟提供，2022 年 4 月]

Enables RNA binding activity. Involved in mitochondrial mRNA processing and regulation of mitochondrial mRNA stability. Located in mitochondrial matrix. [provided by Alliance of Genome Resources, Apr 2022]

TBRG4 基因产物(4)

mRNA Protein Name
NM_001261834.2 NP_001248763.1 FAST kinase domain-containing protein 4 isoform 3
NM_004749.4 NP_004740.2 FAST kinase domain-containing protein 4 isoform 1
NM_030900.4 NP_112162.1 FAST kinase domain-containing protein 4 isoform 2
NM_199122.3 NP_954573.1 FAST kinase domain-containing protein 4 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in mRNA metabolic process IMP
IMP: 通过突变表型推断
28335001 GOA
involved in mitochondrial mRNA processing IMP
IMP: 通过突变表型推断
28335001 GOA
involved in regulation of mitochondrial mRNA stability IMP
IMP: 通过突变表型推断
28335001 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial matrix IDA
IDA: 通过直接分析推断
28335001 GOA
located in mitochondrion IDA
IDA: 通过直接分析推断
20869947 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TBRG4 蛋白结构

FAST_1

FAST_1: FAST kinase-like protein, subdomain 1 (369 - 437)

FAST_2

FAST_2: FAST kinase-like protein, subdomain 2 (450 - 536)

RAP

RAP: RAP domain (569 - 620)

  • 0
  • 100
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  • 400
  • 500
  • 631 a.a.
蛋白主名 其他名称

FAST kinase domain-containing protein 4

FAST kinase domains 4

TBRG4 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra TBRG4 Q969Z0 FAM9B Homo sapiens Q8IZU0
Y2H Array
25416956
Intra TBRG4 Q969Z0 RETREG3 Homo sapiens Q86VR2
Y2H Array
32296183
Intra TBRG4 Q969Z0 RETREG3 Homo sapiens Q86VR2
Y2H Prey Pooling
32296183
Intra TBRG4 Q969Z0 TNFRSF10D Homo sapiens Q9UBN6
Validated Y2H
32296183
Intra TBRG4 Q969Z0 TNFRSF10D Homo sapiens Q9UBN6
Y2H Prey Pooling
32296183
Intra TBRG4 Q969Z0 TNFRSF10D Homo sapiens Q9UBN6
Y2H Array
32296183
Intra TBRG4 Q969Z0 FAM114A2 Homo sapiens Q9NRY5
Y2H Prey Pooling
32296183
Intra TBRG4 Q969Z0 FAM114A2 Homo sapiens Q9NRY5
Validated Y2H
32296183
Intra TBRG4 Q969Z0 FAM114A2 Homo sapiens Q9NRY5
Y2H Array
32296183
Intra TBRG4 Q969Z0 TFIP11 Homo sapiens Q9UBB9
Y2H Prey Pooling
32296183
Intra TBRG4 Q969Z0 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
32296183
Intra TBRG4 Q969Z0 TFIP11 Homo sapiens Q9UBB9
Y2H Array
32296183
Intra TBRG4 Q969Z0 CDR2L Homo sapiens Q86X02
Y2H Prey Pooling
32296183
Intra TBRG4 Q969Z0 CDR2L Homo sapiens Q86X02
Y2H Array
32296183
Intra TBRG4 Q969Z0 AGTRAP Homo sapiens Q6RW13-2
Y2H Prey Pooling
32296183
Intra TBRG4 Q969Z0 AGTRAP Homo sapiens Q6RW13-2
Y2H Array
32296183
Intra TBRG4 Q969Z0 CMTM5 Homo sapiens Q96DZ9-2
Y2H Prey Pooling
32296183
Intra TBRG4 Q969Z0 CMTM5 Homo sapiens Q96DZ9-2
Validated Y2H
32296183
Intra TBRG4 Q969Z0 CMTM5 Homo sapiens Q96DZ9-2
Y2H Array
32296183
Intra TBRG4 Q969Z0 TMEM239 Homo sapiens Q8WW34-2
Y2H Array
32296183
Intra TBRG4 Q969Z0 TMEM239 Homo sapiens Q8WW34-2
Y2H Prey Pooling
32296183
Intra TBRG4 Q969Z0 BICD2 Homo sapiens Q8TD16-2
Y2H Prey Pooling
32296183
Intra TBRG4 Q969Z0 BICD2 Homo sapiens Q8TD16-2
Y2H Array
32296183
Intra TBRG4 Q969Z0 PRB3 Homo sapiens Q04118
Y2H Array
32296183
Intra TBRG4 Q969Z0 PRB3 Homo sapiens Q04118
Y2H Prey Pooling
32296183
Intra TBRG4 Q969Z0 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
Intra TBRG4 Q969Z0 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
Intra TBRG4 Q969Z0 CMTM4 Homo sapiens Q8IZR5-2
Y2H Array
32296183
Intra TBRG4 Q969Z0 CMTM4 Homo sapiens Q8IZR5-2
Y2H Prey Pooling
32296183
Intra TBRG4 Q969Z0 HSD17B13 Homo sapiens Q7Z5P4
Y2H Prey Pooling
32296183
Intra TBRG4 Q969Z0 HSD17B13 Homo sapiens Q7Z5P4
Y2H Array
32296183
Intra TBRG4 Q969Z0 LIME1 Homo sapiens Q9H400
Y2H Prey Pooling
32296183
Intra TBRG4 Q969Z0 LIME1 Homo sapiens Q9H400
Validated Y2H
32296183
Intra TBRG4 Q969Z0 LIME1 Homo sapiens Q9H400
Y2H Array
32296183
Intra TBRG4 Q969Z0 SFT2D1 Homo sapiens Q8WV19
Y2H Array
32296183
Intra TBRG4 Q969Z0 SFT2D1 Homo sapiens Q8WV19
Y2H Prey Pooling
32296183
Intra TBRG4 Q969Z0 KRT27 Homo sapiens Q7Z3Y8
Y2H Array
32296183
Intra TBRG4 Q969Z0 KRT27 Homo sapiens Q7Z3Y8
Y2H Prey Pooling
32296183
Intra TBRG4 Q969Z0 GPRASP2 Homo sapiens Q96D09
Y2H Prey Pooling
32296183
Intra TBRG4 Q969Z0 GPRASP2 Homo sapiens Q96D09
Y2H Array
32296183
Intra TBRG4 Q969Z0 GPRASP2 Homo sapiens Q96D09
Validated Y2H
32296183
Intra TBRG4 Q969Z0 CALCOCO2 Homo sapiens Q13137
Y2H Prey Pooling
25416956
Intra TBRG4 Q969Z0 AGTRAP Homo sapiens Q6RW13
Y2H Prey Pooling
25416956
Intra TBRG4 Q969Z0 AGTRAP Homo sapiens Q6RW13
Validated Y2H
25416956
Intra TBRG4 Q969Z0 BSND Homo sapiens Q8WZ55
Y2H Prey Pooling
32296183
Intra TBRG4 Q969Z0 BSND Homo sapiens Q8WZ55
Y2H Array
32296183
Intra TBRG4 Q969Z0 MAL2 Homo sapiens Q969L2
Validated Y2H
25416956
Intra TBRG4 Q969Z0 MAL2 Homo sapiens Q969L2
Y2H Array
25416956
Intra TBRG4 Q969Z0 SCAMP1 Homo sapiens O15126
Y2H Array
32296183
Intra TBRG4 Q969Z0 SCAMP1 Homo sapiens O15126
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14269 TBRG4 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris TBRG4 VGNC VGNC:47168
Rattus norvegicus TBRG4 RGD RGD:1309737
Bos taurus TBRG4 VGNC VGNC:35664
Mus musculus TBRG4 MGD MGI:1100868
Felis catus TBRG4 VGNC VGNC:66000
Macaca mulatta TBRG4 VGNC VGNC:78151
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