2. Stem Cell/Wnt TGF-beta/Smad
  3. TGF-beta/Smad
  4. Livmoniplimab

Livmoniplimab  (Synonyms: 莱莫尼利单抗; ABBV-151; ARGX-115)

目录号: HY-P99708 纯度: 99.25%
COA

摩尔计算器

Livmoniplimab (ABBV-151) 是一种抗 GARP/TGF-β1 单克隆抗体，可以阻止活性 TGF-β1 的释放。Livmoniplimab 在结肠癌小鼠中具有抗肿瘤活性。Livmoniplimab 可用于局部晚期或转移性实体瘤的研究。

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CAS No. : 2412004-88-5

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规格 价格 是否有货 数量
1 mg ￥3100
In-stock
5 mg ￥8050
In-stock
10 mg   询价  
50 mg   询价  

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Customer Review

Livmoniplimab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Livmoniplimab (ABBV-151) is a monoclonal antibody against GARP/TGF-β1 that can inhibit the release of active TGF-β1. Livmoniplimab has anti-tumor activity in colon cancer mice. Livmoniplimab can be used for the study of locally advanced or metastatic solid tumors[1][2].
同型

Human IgG1 kappa
推荐同型对照抗体
种属

Chimeric; Humanized
体内研究
(In Vivo)

Livmoniplimab (250 μg; 每周 3 次; 3 周; 腹腔注射) 在结肠癌小鼠中具有抗肿瘤活性[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 7-week-old female B-hGARP mice subcutaneously inoculated with MC38 mouse colon cancer cells[2].
Dosage: 250 μg
Administration: Intraperitoneal injection (i.p.); three times a week; 3 weeks
Result: Resulted in 34.3% tumor growth inhibition.
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

莱莫尼利单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG4 kappa
纯度 & 产品资料
参考文献

Livmoniplimab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Livmoniplimab2412004-88-5ABBV-151 ARGX-115莱莫尼利单抗ABBV151ABBV 151ARGX115ARGX 115ARGX-115TGF-beta/SmadTransforming growth factor betaantibodyGARP/TGF-β1solid tumorInhibitorinhibitorinhibit

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