2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. MMV667492

MMV667492是一种有效的Ezrin抑制剂，具有抑制骨肉瘤细胞侵袭表型的活性。MMV667492在所有生物学实验中表现出强大的抗Ezrin活性，并且其化合物特性优于NSC305787。MMV667492在斑马鱼胚胎中能够表现出与Ezrin抑制相关的形态缺陷表型。MMV667492还显示出抑制高表达Ezrin的骨肉瘤细胞的肺转移的能力。

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MMV667492 Chemical Structure

MMV667492 Chemical Structure

CAS No. : 380877-02-1

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MMV667492 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MMV667492 is a potent Ezrin inhibitor with the activity to inhibit the invasion phenotype of osteosarcoma cells. MMV667492 exhibited potent anti-Ezrin activity in all biological assays and its compound properties were superior to NSC305787. MMV667492 was able to exhibit morphological defect phenotypes associated with Ezrin inhibition in zebrafish embryos. MMV667492 also showed the ability to inhibit the lung metastasis of osteosarcoma cells that highly expressed Ezrin[1].

分子量

313.35

Formula

C17H19N3O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MMV667492 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MMV667492380877-02-1MMV 667492MMV-667492Endogenous MetaboliteInhibitorinhibitorinhibit

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