2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR
  4. SR 1824

SR 1824 是一种非激动剂 PPARγ 配体，可阻断 Cdk5 介导的磷酸化。SR 1824 具有抗糖尿病的作用。

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SR 1824 Chemical Structure

SR 1824 Chemical Structure

CAS No. : 1338259-06-5

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SR 1824 相关抗体

Top Publications Citing Use of Products

查看 PPAR 亚型特异性产品:

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PPARα PPARβ/δ PPARγ PPAR PPARδ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SR 1824 is a non-agonist PPARγ ligand that blocks Cdk5-mediated phosphorylation. SR 1824 has anti-diabetic effects[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HEK-293T EC50
516 nM
Compound: 37
Transactivation of human PPARgamma in HEK293T cells after 18 hrs by luciferase reporter gene assay
Transactivation of human PPARgamma in HEK293T cells after 18 hrs by luciferase reporter gene assay
[PMID: 26396687]
分子量

581.50

Formula

C33H29BrN2O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SR 1824 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SR 18241338259-06-5SR1824SR-1824PPARPeroxisome proliferator-activated receptorsnon-agonistCdk5phosphorylationanti-diabeticInhibitorinhibitorinhibit

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产品名称：
SR 1824
目录号：
HY-120542
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