2. Anti-infection
  3. Bacterial
  4. Usnic acid

Usnic acid  (Synonyms: 松萝酸)

目录号: HY-N0656 纯度: 98.90%
COA 产品使用指南 技术支持

Usnic acid 是地衣次生代谢产物，具有独特的二苯并呋喃骨架。Usnic acid 具有优异的抗癌和抗菌性能。Usnic acid 通过降低 NFATc1 的转录和翻译表达，显著抑制 RANKL 介导的破骨细胞的形成和功能。

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Usnic acid Chemical Structure

Usnic acid Chemical Structure

CAS No. : 125-46-2

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规格 价格 是否有货 数量
100 mg ￥200
In-stock
500 mg ￥350
In-stock
1 g   询价  
5 g   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of Usnic acid:

Usnic acid 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Usnic acid, a lichen-derived secondary metabolite, has a unique dibenzofuran skeleton. Usnic acid has excellent anticancer and antimicrobial properties. Usnic acid significantly inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HeLa IC50
> 10 μM
Compound: (-)-1
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay
[PMID: 31282672]
HeLa IC50
> 10 μM
Compound: (+)-1
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay
[PMID: 31282672]
HeLa IC50
> 10 μM
Compound: (-)-1
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay
[PMID: 31282672]
HeLa IC50
10 μM
Compound: (+)-1
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay
[PMID: 31282672]
MCF7 IC50
> 10 μM
Compound: (-)-1
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTT assay
[PMID: 31282672]
MCF7 IC50
> 10 μM
Compound: (+)-1
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTT assay
[PMID: 31282672]
MCF7 IC50
> 10 μM
Compound: (-)-1
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
[PMID: 31282672]
MCF7 IC50
10 μM
Compound: (+)-1
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
[PMID: 31282672]
PC-3 IC50
> 10 μM
Compound: (-)-1
Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 24 hrs by MTT assay
Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 24 hrs by MTT assay
[PMID: 31282672]
PC-3 IC50
> 10 μM
Compound: (+)-1
Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 24 hrs by MTT assay
Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 24 hrs by MTT assay
[PMID: 31282672]
PC-3 IC50
> 10 μM
Compound: (-)-1
Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay
[PMID: 31282672]
PC-3 IC50
> 10 μM
Compound: (+)-1
Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay
[PMID: 31282672]
分子量

344.32

Formula

C18H16O7
CAS 号
性状

固体

颜色

White to yellow

中文名称

松萝酸
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
细胞实验： 

DMSO 中的溶解度 : 3.33 mg/mL (9.67 mM; 超声助溶 (<60°C); 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.9043 mL 14.5214 mL 29.0428 mL
5 mM 0.5809 mL 2.9043 mL 5.8085 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物实验：

以下溶解方案，请直接配制工作液。建议现用现配，在短期内尽快用完。 以下溶剂前显示的百分比是指该溶剂在您配制终溶液中的体积占比； 如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶。

  • 方案 一

    请依序添加每种溶剂： 50% PEG300    50% Saline

    Solubility: 2 mg/mL (5.81 mM); 悬浊液; 超声助溶

  • 方案 二

    请依序添加每种溶剂： 0.5% CMC-Na/saline water

    Solubility: 2 mg/mL (5.81 mM); 悬浊液; 超声助溶

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: 98.90%

COA (296 KB) HNMR (251 KB) RP-HPLC (261 KB) LCMS (97 KB)

产品使用指南 (1538 KB)
参考文献

Usnic acid 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9043 mL 14.5214 mL 29.0428 mL 72.6069 mL
5 mM 0.5809 mL 2.9043 mL 5.8086 mL 14.5214 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Usnic acid125-46-2松萝酸BacterialsecondarymetaboliteskeletonanticancerantimicrobialosteoclastformationInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-N0656
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