1. GPCR/G Protein
  2. GCGR
  3. Volagidemab

Volagidemab  (Synonyms: 沃拉德单抗; REMD-477; AMG-477)

目录号: HY-P99383 纯度: 98.43%
COA

Volagidemab 是一种拮抗性 胰高血糖素受体 (GCGR) 单克隆抗体 (mAb)。Volagidemab 可用于1型糖尿病 (T1D) 的研究。

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CAS No. : 1233956-13-2

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规格 价格 是否有货 数量
1 mg ¥3000
In-stock
5 mg ¥7800
In-stock
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Volagidemab is an antagonistic glucagon receptor (GCGR) monoclonal antibody (mAb). Volagidemab can be used in the research of type 1 diabetes (T1D)[1][2].

同型

Human IgG2 kappa

推荐同型对照抗体
种属

Human

体内研究
(In Vivo)

Volagidemab (5 mg/kg,皮下注射) 在四氧嘧啶诱导的糖尿病小鼠中抑制 1 型糖尿病表型[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Alloxan-induced diabetic mice [2]
Dosage: 5 mg/kg
Administration: Subcutaneous injection (s.c.)
Result: Reduced phosphorylated CREB protein and PEPCK protein expression to nondiabetic levels.
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

沃拉德单抗

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • Human IgG2 kappa
纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Volagidemab
目录号:
HY-P99383
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