2. Gene
  3. SGF29 - SAGA complex associated factor 29 Gene

SGF29 - SAGA complex associated factor 29 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：SAGA 复合体相关因子 29

种属: Homo sapiens

同用名: STAF36; TDRD29; CCDC101

基因 ID: 112869 | 基因类型: protein coding

关于 SGF29

Cytogenetic location: 16p11.2 Genomic coordinates (GRCh38): 16:28,553,920-28,591,790 (from NCBI)

This gene has 7 transcripts (splice variants) and 199 orthologues. Ubiquitous expression in testis (RPKM 13.2), ovary (RPKM 12.9) and 25 other tissues.

功能概要

CCDC101 是 2 个组蛋白乙酰转移酶复合物的亚基：包含 ADA2A (TADA2A；MIM 602276) 的 (ATAC) 复合物和 SPT3 (SUPT3H；MIM 602947) -TAF9 (MIM 600822) -GCN5 (KAT2A；MIM 602301) /PCAF ( KAT2B；MIM 602303) 乙酰化酶 (STAGA) 复合物。这两种复合物都含有 GCN5 或 PCAF，它们是同源乙酰转移酶 (Wang 等人，2008 [PubMed 18838386]) 。[OMIM 提供，2010 年 4 月]

CCDC101 is a subunit of 2 Histone Acetyltransferase complexes: the ADA2A (TADA2A; MIM 602276)-containing (ATAC) complex and the SPT3 (SUPT3H; MIM 602947)-TAF9 (MIM 600822)-GCN5 (KAT2A; MIM 602301)/PCAF (KAT2B; MIM 602303) acetylase (STAGA) complex. Both of these complexes contain either GCN5 or PCAF, which are paralogous acetyltransferases (Wang et al., 2008 [PubMed 18838386]).[supplied by OMIM, Apr 2010]

SGF29 基因产物(1)

mRNA Protein Name
NM_138414.3 NP_612423.1 SAGA-associated factor 29
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables methylated histone binding IDA
IDA: 通过直接分析推断
20850016 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
18838386 GOA
involved in regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
19936620 GOA
involved in regulation of cell cycle IMP
IMP: 通过突变表型推断
19103755 GOA
involved in regulation of cell division IDA
IDA: 通过直接分析推断
20562830 GOA
involved in regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
22055187 GOA
involved in regulation of tubulin deacetylation IMP
IMP: 通过突变表型推断
20562830 GOA
involved in response to endoplasmic reticulum stress IMP
IMP: 通过突变表型推断
23894581 GOA
involved in transcription initiation-coupled chromatin remodeling IMP
IMP: 通过突变表型推断
23894581 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of ATAC complex IDA
IDA: 通过直接分析推断
18838386 GOA
part of SAGA-type complex IDA
IDA: 通过直接分析推断
18838386 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SGF29 蛋白结构

DUF1325

DUF1325: SGF29 tudor-like domain (158 - 288)

  • 0
  • 100
  • 200
  • 293 a.a.
蛋白主名 其他名称

SAGA-associated factor 29

SAGA-associated factor 29 homolog

SGF29 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SGF29 Q96ES7 KRT13 Homo sapiens A1A4E9
Y2H Prey Pooling
25416956
Intra SGF29 Q96ES7 CCDC102B Homo sapiens Q68D86
Y2H Prey Pooling
25416956
Intra SGF29 Q96ES7 CLHC1 Homo sapiens Q8NHS4
Y2H Array
25416956
Intra SGF29 Q96ES7 CLHC1 Homo sapiens Q8NHS4
Y2H Prey Pooling
25416956
Intra SGF29 Q96ES7 SYCE3 Homo sapiens A1L190
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 SYCE3 Homo sapiens A1L190
Y2H Array
32296183
Intra SGF29 Q96ES7 KRT33B Homo sapiens Q14525
Y2H Array
32296183
Intra SGF29 Q96ES7 KRT33B Homo sapiens Q14525
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 TFIP11 Homo sapiens Q9UBB9
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
32296183
Intra SGF29 Q96ES7 TFIP11 Homo sapiens Q9UBB9
Y2H Array
32296183
Intra SGF29 Q96ES7 PROSER3 Homo sapiens Q2NL68
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 PROSER3 Homo sapiens Q2NL68
Y2H Array
32296183
Intra SGF29 Q96ES7 TRAF3IP1 Homo sapiens Q8TDR0-2
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 TRAF3IP1 Homo sapiens Q8TDR0-2
Y2H Array
32296183
Intra SGF29 Q96ES7 TEX12 Homo sapiens Q9BXU0
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 TEX12 Homo sapiens Q9BXU0
Validated Y2H
32296183
Intra SGF29 Q96ES7 TEX12 Homo sapiens Q9BXU0
Y2H Array
32296183
Intra SGF29 Q96ES7 LZTS1 Homo sapiens Q9Y250
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 LZTS1 Homo sapiens Q9Y250
Validated Y2H
32296183
Intra SGF29 Q96ES7 LZTS1 Homo sapiens Q9Y250
Y2H Array
32296183
Intra SGF29 Q96ES7 DBF4B Homo sapiens Q8NFT6-2
Y2H Array
32296183
Intra SGF29 Q96ES7 DBF4B Homo sapiens Q8NFT6-2
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 TCF4 Homo sapiens P15884-3
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 TCF4 Homo sapiens P15884-3
Y2H Array
32296183
Intra SGF29 Q96ES7 KIF2C Homo sapiens Q99661
Anti Tag CoIP
33961781
Intra SGF29 Q96ES7 MYF5 Homo sapiens P13349
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 MYF5 Homo sapiens P13349
Y2H Array
32296183
Intra SGF29 Q96ES7 C20orf202 Homo sapiens A1L168
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 C20orf202 Homo sapiens A1L168
Y2H Array
32296183
Intra SGF29 Q96ES7 KRT24 Homo sapiens Q2M2I5
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 KRT24 Homo sapiens Q2M2I5
Y2H Array
32296183
Intra SGF29 Q96ES7 KRT27 Homo sapiens Q7Z3Y8
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 KRT27 Homo sapiens Q7Z3Y8
Y2H Array
32296183
Intra SGF29 Q96ES7 SYNPO Homo sapiens Q8N3V7
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 SYNPO Homo sapiens Q8N3V7
Y2H Array
32296183
Intra SGF29 Q96ES7 KRT16 Homo sapiens P08779
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 KRT16 Homo sapiens P08779
Y2H Array
32296183
Intra SGF29 Q96ES7 KNSTRN Homo sapiens Q9Y448
Y2H Array
32296183
Intra SGF29 Q96ES7 KNSTRN Homo sapiens Q9Y448
Anti Tag CoIP
33961781
Intra SGF29 Q96ES7 KNSTRN Homo sapiens Q9Y448
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 KNSTRN Homo sapiens Q9Y448
Validated Y2H
32296183
Intra SGF29 Q96ES7 MED4 Homo sapiens Q9NPJ6
Y2H Array
25416956
Intra SGF29 Q96ES7 MED4 Homo sapiens Q9NPJ6
Y2H Prey Pooling
25416956
Intra SGF29 Q96ES7 MED4 Homo sapiens Q9NPJ6
Validated Y2H
25416956
Intra SGF29 Q96ES7 MED11 Homo sapiens Q9P086
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 MED11 Homo sapiens Q9P086
Validated Y2H
32296183
Intra SGF29 Q96ES7 MED11 Homo sapiens Q9P086
Y2H Array
32296183
Intra SGF29 Q96ES7 TADA3 Homo sapiens O75528
Anti Tag CoIP
33961781
Intra SGF29 Q96ES7 TADA3 Homo sapiens O75528
TAP
24981860
Intra SGF29 Q96ES7 TADA3 Homo sapiens O75528
Anti Tag CoIP
28514442
Intra SGF29 Q96ES7 TADA3 Homo sapiens O75528
Validated Y2H
25416956
Intra SGF29 Q96ES7 TADA3 Homo sapiens O75528
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 TADA3 Homo sapiens O75528
Anti Tag CoIP
26496610
Intra SGF29 Q96ES7 TADA3 Homo sapiens O75528
Y2H Array
25416956
Intra SGF29 Q96ES7 TADA3 Homo sapiens O75528
Y2H Array
32296183
Intra SGF29 Q96ES7 TCF4 Homo sapiens P15884
Validated Y2H
25416956
Intra SGF29 Q96ES7 TCF4 Homo sapiens P15884
Y2H Array
25416956
Intra SGF29 Q96ES7 TCF4 Homo sapiens P15884
Anti Tag CoIP
33961781
Intra SGF29 Q96ES7 NDC80 Homo sapiens O14777
Y2H Prey Pooling
25416956
Intra SGF29 Q96ES7 NDC80 Homo sapiens O14777
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 NDC80 Homo sapiens O14777
Anti Tag CoIP
33961781
Intra SGF29 Q96ES7 NDC80 Homo sapiens O14777
Y2H Array
32296183
Intra SGF29 Q96ES7 NDC80 Homo sapiens O14777
Y2H Array
25416956
Intra SGF29 Q96ES7 NDC80 Homo sapiens O14777
MAPPIT
25416956
Intra SGF29 Q96ES7 ITPRID2 Homo sapiens P28290
Anti Tag CoIP
33961781
Intra SGF29 Q96ES7 RINT1 Homo sapiens Q6NUQ1
Y2H Array
31515488
Intra SGF29 Q96ES7 RINT1 Homo sapiens Q6NUQ1
Validated Y2H
25416956
Intra SGF29 Q96ES7 RINT1 Homo sapiens Q6NUQ1
Y2H Array
25416956
Intra SGF29 Q96ES7 RINT1 Homo sapiens Q6NUQ1
Y2H Array
32296183
Intra SGF29 Q96ES7 RINT1 Homo sapiens Q6NUQ1
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 KRT15 Homo sapiens P19012
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 KRT15 Homo sapiens P19012
Y2H Array
32296183
Intra SGF29 Q96ES7 KRT15 Homo sapiens P19012
Y2H Array
25416956
Intra SGF29 Q96ES7 LNX1 Homo sapiens Q8TBB1
Y2H Array
25416956
Intra SGF29 Q96ES7 KRT19 Homo sapiens P08727
Y2H Array
32296183
Intra SGF29 Q96ES7 KRT19 Homo sapiens P08727
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 H3C1 Homo sapiens P68431
X-Ray Diffraction
21685874
Intra SGF29 Q96ES7 H3C1 Homo sapiens P68431
FPS
21685874
Intra SGF29 Q96ES7 H3C1 Homo sapiens P68431
ITC
21685874
Intra SGF29 Q96ES7 BECN1 Homo sapiens Q14457
Y2H Array
32296183
Intra SGF29 Q96ES7 BECN1 Homo sapiens Q14457
Y2H Prey Pooling
32296183
Intra SGF29 Q96ES7 BECN1 Homo sapiens Q14457
Anti Tag CoIP
33961781
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-158009 SGF29-IN-1 Inhibitor ≥98.0% 否
HY-RS12796 SGF29 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SGF29 RGD RGD:1310609
Macaca mulatta SGF29 VGNC VGNC:97827
Mus musculus SGF29 MGD MGI:1922815
Bos taurus SGF29 VGNC VGNC:97311
Felis catus SGF29 VGNC VGNC:97623
Canis familiaris SGF29 VGNC VGNC:97220
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