CLK1 - CDC like kinase 1 Gene

中文名称：CDC 样激酶 1

种属: Homo sapiens

同用名: CLK; STY; CLK/STY

关于 CLK1

功能概要

该基因编码双特异性蛋白激酶类 CDC2 (或 LAMMER) 家族的成员。在细胞核中，编码的蛋白质磷酸化参与 pre-mRNA 加工的富含丝氨酸/精氨酸的蛋白质，将它们释放到核质中。 pre-mRNA 加工过程中剪接位点的选择可能受交易因子浓度的调节，包括富含丝氨酸/精氨酸的蛋白质。因此，编码的蛋白质可能在控制剪接位点选择中发挥间接作用。已发现该基因编码不同异构体的多个转录变体。[RefSeq 提供，2009 年 6 月]

This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]