NUP54 - nucleoporin 54 Gene

中文名称：核孔蛋白 54

种属: Homo sapiens

关于 NUP54

功能概要

核膜在真核细胞中产生不同的核和细胞质区室。它由两个由核孔穿孔的同心膜组成，大型蛋白质复合物形成水通道以调节细胞核和细胞质之间大分子的流动。这些复合物由至少 100 个不同的多肽亚基组成，其中许多属于核孔蛋白家族。该基因编码含有 phe-gly (FG) 重复序列的核孔蛋白子集的成员。已发现该基因的多个选择性剪接转录物变体。[RefSeq 提供，2013 年 6 月]

The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the phe-gly (FG) repeat-containing nucleoporin subset. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]